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利培酮-risperidone
记事
good response = 50% reduction in PANSS score. Authors state "At the same time, rs7627954 was also found to be associated with antipsychotic drug responses under codominant, recessive and log-additive genetic models (p = 0.033; p = 0.012; and p = 0.022, respectively). In the best model (recessive), genotype C/C was more prevalent in good responders than in poor responders "
专家论述
Genotype CC is associated with increased response to risperidone in people with Schizophrenia as compared to genotypes CT + TT.