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(S)-美沙酮-(S)-methadone
变量_单倍型
CYP2B6*1, CYP2B6*6, CYP2B6*7, CYP2B6*9, CYP2B6*18
记事
effect was reported as "S-methadone clearance was significantly associated with CYP2B6 polymorphisms, specifically the number of CYP2B6 slow metabolizer alleles" and listed "CYP2B6 slow metabolizer alleles in the study population included *6,*7,*9,*18"
专家论述
CYP2B6 *6 + *7 + *9 + *18 is associated with decreased clearance of (S)-methadone in children with Scoliosis as compared to CYP2B6 *1/*1.