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利尿剂，“氢氯噻嗪”，“普通噻嗪类”-diuretics,"hydrochlorothiazide","Thiazides, plain"
药物名称(英)
diuretics,"hydrochlorothiazide","Thiazides, plain"
药物名称(中)
利尿剂，“氢氯噻嗪”，“普通噻嗪类”
记事
The association was with systolic blood pressure response. Observations: 2.91 mm Hg increased reduction of systolic blood pressure per T allele in PEAR + GERA, 0.39 mm Hg increased reduction of systolic blood pressure per T allele in NORDIL, and 2.34 mm Hg increased reduction of systolic blood pressure per T allele in PEAR + GERA + NORDIL. This association was significant in PEAR + GERA but not in the replication cohort NORDIL nor in the 3 cohort meta-analysis.
专家论述
Allele T is associated with increased response to diuretics, hydrochlorothiazide or Thiazides, plain in people with Hypertension as compared to allele C.