当前位置：药药网 / 数据中心 /变体注释摘要_药物剂量、反应、代谢
ivacaftor / lumacaftor-ivacaftor / lumacaftor
药物名称(英)
ivacaftor / lumacaftor
药物名称(中)
ivacaftor / lumacaftor
记事
A455E allele. Rectal organoids carrying the A455E allele showed increased CFTR function as measured by FIS and SLA assay. Authors predict that cystic fibrosis patients carrying the A455E allele would have a clinical response to ivacaftor/lumacaftor treatment.
专家论述
Allele A is associated with response to ivacaftor / lumacaftor.