当前位置：药药网 / 数据中心 /变体注释摘要_药物剂量、反应、代谢
可待因-codeine
变量_单倍型
CYP2D6 poor metabolizer phenotype
记事
Healthy volunteers were previously phenotyped using debrisoquine. A negative correlation between debrisoquine metabolic ratio and levels of O-demethylated codeine metabolites was found.
专家论述
CYP2D6 poor metabolizer phenotype is associated with decreased metabolism of codeine in healthy individuals as compared to CYP2D6 normal metabolizer phenotype.