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美沙酮-methadone
记事
Patients with the CC genotype had a lower 'negative rate of morphine urine test' than patients with the CT or TT genotypes. However, this SNP was not significantly associated with MMT compliance in the study. Note that although this variant is located in MTRF1L, it is discussed in the paper as being an OPRM1 SNP. Please note that alleles have been complemented to the positive strand.
专家论述
Genotype CC is associated with decreased response to methadone in people with Heroin Dependence as compared to genotypes CT + TT.