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依法韦仑-efavirenz
记事
Patients with the TT genotype had higher plasma efavirenz concentrations compared to patients with the GG genotype: 2.50 mg/L [0.98-10.00] for GG genotype vs 8.78 mg/L [4.77-10.00] for TT genotype; P=0.005.
专家论述
Genotype TT is associated with decreased clearance of efavirenz in people with HIV Infections as compared to genotype GT.