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华法林-warfarin
记事
in han chinese. The SNP POR*37 831-35C>T was shown to be a minor but statistically significant factor associated with inter-individual variation in warfarin maintenance dose in Han Chinese. The contribution of POR*37 831-35C>T to warfarin dose variation was only 3.9 %.
专家论述
Genotypes CT + TT are associated with increased dose of warfarin as compared to genotype CC.