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二甲双胍-metformin
记事
Subjects were at high risk of diabetes and were recruited from Diabetes Prevention Program (DPP) and were followed for a year. The authors measured changes in response to insulin at baseline and one year after treatment. The C allele was significantly associated with response to Metformin (vs. Placebo).
专家论述
Genotype CG is associated with increased response to metformin as compared to genotype GG.