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伏立康唑-voriconazole
记事
authors reports values for CYP2C9*3 allele carriers vs noncarriers. Authors state "10.3% (7 patients) were heterozygous for CYP2C9*3. The homozygous mutation was not found in our cohort". CYP2C9*13 allele was tested for and not observed.
专家论述
Genotypes AA + AC is not associated with increased dose-adjusted trough concentrations of voriconazole in children as compared to genotype CC.