地高辛-digoxin
注释ID
982044285
变量_单倍型
rs2032582
基因
ABCB1
药物名称(英)
digoxin
药物名称(中)
地高辛
PMID
17652833
类型
Metabolism/PK
含义
yes
记事
and CT combined. Patients with the AA + AT genotypes had an increased digoxin serum/saliva concentration ratio as compared to those with the AC + CT genotypes. Combined group of those receiving P-glycoprotein inhibitors (n = 31) and those not receiving P-glycoprotein inhibitors (n = 46). Please note alleles have been complemented to the plus chromosomal strand.
专家论述
Genotypes AA + AT are associated with decreased clearance of digoxin in people with Heart Failure as compared to genotype AC.
等位基因
AA + AT
专家评论
备注
变体注释摘要
id研究类型特征类型
26063 cohort Study Cohort
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