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他克莫司-tacrolimus
记事
All liver transplant recipients were given tacrolimus 2-3 days post liver transplantation. Weight adjusted dose and concentration to dose ratio (C/D) were the primary outcomes. Dose and C/D were calculated based on measurements taken on day 3, 7 and 14 post-transplantation as well as the the 1st, 3rd, 6th and 12th month post-transplantation. ABCB1 genotype was not significantly associated with C/D of tacrolimus at any time point.
专家论述
Genotype TT is not associated with concentrations of tacrolimus in children with liver transplantation.