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环孢素-cyclosporine
记事
The daily dose requirement of cyclosporine increased with presence of the C allele (i.e. CC > AC > CT > AA). Those who carried a C allele had increased dose requirements as compared to those with the AA genotype at 3 (p=0.024), 6 (p=0.017) and 9 months (p=0.004) post-transplant. Please note alleles have been complemented to the plus chromosomal strand.
专家论述
Genotypes AC + CC is associated with increased dose of cyclosporine in people with Kidney Transplantation as compared to genotypes AA + CT.