阿糖胞苷、“柔红霉素”、“右雷佐生”-cytarabine,"daunorubicin","dexrazoxane",变体注释摘要_药物剂量、反应、代谢

阿糖胞苷、“柔红霉素”、“右雷佐生”-cytarabine,"daunorubicin","dexrazoxane"

注释ID

1446897929

变量_单倍型

rs2032582

基因

ABCB1

药物名称(英)

cytarabine,"daunorubicin","dexrazoxane"

药物名称(中)

阿糖胞苷、“柔红霉素”、“右雷佐生”

PMID

25567217

类型

Efficacy

含义

no

记事

In univariate analysis the SNP was associated with overall survival (OS) and relapse free survival (RFS) but did not remain significant in multivariate analysis. It was only significant when considered as part of a haplotype (ABCB1*2 (PMID: 11503014)).

专家论述

Genotype AA is not associated with response to cytarabine, daunorubicin and dexrazoxane in people with Leukemia, Myeloid, Acute as compared to genotypes AC + CC.

等位基因

AA

专家评论

备注

变体注释摘要