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他克莫司-tacrolimus
记事
Dose normalized tacrolimus exposure was decreased in patients with the CT genotype (CYP3A5 *1/*3) (N=5): at baseline, and at 1.5 hours and 1 week post-dosing as compared with the CC (CYP3A5 *3/*3) genotype (n=23, P=0.033).
专家论述
Genotype CT is associated with decreased exposure to tacrolimus in people with Kidney Transplantation as compared to genotype CC.