当前位置：药药网 / 数据中心 /变体注释摘要_药物剂量、反应、代谢
他克莫司-tacrolimus
记事
As measured by dose-adjusted concentrations, CYP3A5 *1/*1 (TT) and *1/*3 (CT) required significantly higher doses to achieve the targeted tacrolimus serum concentrations than the CYP3A5*3/*3 (CC) genotypes.
专家论述
Genotypes CT + TT is associated with increased dose of tacrolimus in people with Kidney Transplantation as compared to genotype CC.