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尼古丁-nicotine
变量_单倍型
CYP2A6*1A, CYP2A6*1B1, CYP2A6*4A
记事
Please note that the *46 allele is described as the *1B1 allele in the paper and has subsequently been reassigned by PharmVar.
专家论述
CYP2A6 *4A/*4A is associated with decreased metabolism of nicotine in healthy individuals as compared to CYP2A6 *1A/*1A + *1A/*46 + *1A/*4A.