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尼古丁-nicotine
变量_单倍型
CYP2A6*1A, CYP2A6*1B1
记事
Includes alleles *1B1-*1B15. Please note that the *46 allele is described as the *1B1 allele in the paper and has subsequently been reassigned by PharmVar.
专家论述
CYP2A6 *1A/*46 is associated with increased clearance of nicotine as compared to CYP2A6 *1A/*1A.