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替加氟-tegafur
变量_单倍型
CYP2A6*1A, CYP2A6*4A, CYP2A6*11
记事
The individual case study had one deleted allele (originally identified as *4C) and a novel allele now defined as *11 (670T>C, Ser244Pro).
专家论述
CYP2A6 *11/*4A is associated with decreased metabolism of tegafur in people with Stomach Neoplasms as compared to CYP2A6 *1A/*1A.