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羟基马尿酸
生物标志物(英)
Hydroxyhippuric acid
生物种群
志愿者们吃了一份标准化的测试早餐，早餐中含有四种测试食物之一（鲑鱼、花椰菜、覆盆子、全麦饼干）
生物种群(英)
Volunteers fed a standardized test breakfast containing one of 4 tested foods (salmon, broccoli, raspberry, whole-grain wheat biscuits)
同类人(英)
MEDE (MEtabolomics to characterise Dietary Exposure)
分析方法
Mass spectrometry (MS)
干预剂量
60 g smoked salmon trimmings or 200 g steamed broccoli florets or 200 g raspberries or 2 biscuits
结构识别
Accurate masses queried against MZedDB, fragmentation analysis (FT-ICR-MS and FIE-MSn) of commercial standards, comparisons with spectra in public databases and literature. Match 3- and 4-hydroxyhippuric acid.
特征选择
Random forest (significant at IS > 0.002) ; ROC (significant at AUC > 0.90) ; Welch's t-test with p-value correction (significant at p < 1x10-5)