版本
5.0
创建日期
2005-11-16 15:48:42 UTC
更新日期
2021-09-14 15:47:20 UTC
登录号
HMDB0000061
地位
quantified
二级访问
HMDB0001468

HMDB00061

HMDB01468

名称
Adenosine 3',5'-diphosphate
描述
Adenosine 3', 5'-diphosphate or PAP is a nucleotide that is closely related to ADP. It has two phosphate groups attached to the 5' and 3' positions of the pentose sugar ribose (instead of pyrophosphoric acid at the 5' position, as found in ADP), and the nucleobase adenine. PAP is converted to PAPS by Sulfotransferase and then back to PAP after the sulfotransferase reaction. Sulfotransferase (STs) catalyze the transfer reaction of the sulfate group from the ubiquitous donor 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to an acceptor group of numerous substrates. This reaction, often referred to as sulfuryl transfer, sulfation, or sulfonation, is widely observed from bacteria to humans and plays a key role in various biological processes such as cell communication, growth and development, and defense. PAP also appears to a role in bipolar depression. Phosphatases converting 3'-phosphoadenosine 5'-phosphate (PAP) into adenosine 5'-phosphate are of fundamental importance in living cells as the accumulation of PAP is toxic to several cellular systems. These enzymes are lithium-sensitive and we have characterized a human PAP phosphatase as a potential target of lithium therapy.
同义词
1:3'-Phosphoadenylate

2:Adenosine 3',5'-bisphosphate

3:PAP

4:Phosphoadenosine phosphate

5:3'-Phosphoadenylic acid

6:Adenosine 3',5'-bisphosphoric acid

7:Phosphoadenosine phosphoric acid

8:Adenosine 3',5'-diphosphoric acid

9:3'-Phosphoryl-AMP

10:3,5-ADP

11:3,5-Diphosphoadenosine

12:3-Phosphoadenosine 5-phosphate

13:5-(Dihydrogen phosphate) 3-adenylate

14:5-(Dihydrogen phosphate)3'-adenylic acid

15:Adenosine 3,5-bis

16:Adenosine 3,5-bisphosphate

17:Adenosine 3'-phosphate-5'-phosphate, disodium salt

18:3'-Phosphoadenosine 5'-phosphate

19:Adenosine 3'-phosphate-5'-phosphate, monosodium salt

20:3',5'-ADP

21:Adenosine 3'-phosphate-5'-phosphate

化学式
C10H15N5O10P2
平均分子量
427.2011
等位分子量
427.029414749
化学名称
{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid
传统名称
adenosine 3',5'-bisphosphate
CAS 登记号
1053-73-2
代谢物结构字符串
NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H]3O)C2=NC=N1
inchi标识符
InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(25-27(20,21)22)4(24-10)1-23-26(17,18)19/h2-4,6-7,10,16H,1H2,(H2,11,12,13)(H2,17,18,19)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1
印记键
WHTCPDAXWFLDIH-KQYNXXCUSA-N
分类学
description: belongs to the class of organic compounds known as purine ribonucleoside 3',5'-bisphosphates. These are purine ribobucleotides with one phosphate group attached to 3' and 5' hydroxyl groups of the ribose moiety.

description:Purine ribonucleoside 3',5'-bisphosphates

kingdom:Organic compounds

super_class:Nucleosides, nucleotides, and analogues

class:Purine nucleotides

sub_class:Purine ribonucleotides

molecular_framework:Aromatic heteropolycyclic compounds

1:6-aminopurines

2:Aminopyrimidines and derivatives

3:Azacyclic compounds

4:Glycosylamines

5:Heteroaromatic compounds

6:Hydrocarbon derivatives

7:Imidolactams

8:Monoalkyl phosphates

9:Monosaccharide phosphates

10:N-substituted imidazoles

11:Organic oxides

12:Organopnictogen compounds

13:Oxacyclic compounds

14:Pentose phosphates

15:Primary amines

16:Purine ribonucleoside monophosphates

17:Ribonucleoside 3'-phosphates

18:Secondary alcohols

19:Tetrahydrofurans

20:6-aminopurine

21:Alcohol

22:Alkyl phosphate

23:Amine

24:Aminopyrimidine

25:Aromatic heteropolycyclic compound

26:Azacycle

27:Azole

28:Glycosyl compound

29:Heteroaromatic compound

30:Hydrocarbon derivative

31:Imidazole

32:Imidazopyrimidine

33:Imidolactam

34:Monoalkyl phosphate

35:Monosaccharide

36:Monosaccharide phosphate

37:N-glycosyl compound

38:N-substituted imidazole

39:Organic nitrogen compound

40:Organic oxide

41:Organic oxygen compound

42:Organic phosphoric acid derivative

43:Organoheterocyclic compound

44:Organonitrogen compound

45:Organooxygen compound

46:Organopnictogen compound

47:Oxacycle

48:Pentose monosaccharide

49:Pentose phosphate

50:Pentose-5-phosphate

51:Phosphoric acid ester

52:Primary amine

53:Purine

54:Purine ribonucleoside 3',5'-bisphosphate

55:Purine ribonucleoside monophosphate

56:Pyrimidine

57:Ribonucleoside 3'-phosphate

58:Secondary alcohol

59:Tetrahydrofuran

60:adenosine bisphosphate

本体论
term:Disposition

definition:A concept that describes the origin of a chemical, its location within an organism, or its route of exposure.

parent_id:

level:1

type:parent

term:Route of exposure

definition:A mean by which a chemical agent comes in contact with an organism, either under intended or unintended circumstances.

parent_id:7724

*level:2

type:parent

term:Enteral

definition:Chemical exposure via the alimentary canal (mouth to anus).

parent_id:7743

**level:3

type:parent

term:Ingestion

definition:Chemical exposure facilitated by entry through the mouth.

parent_id:7744

***level:4

type:child

synonym:Digestion

term:Source

definition:Natural or synthetic origin of a chemical.

parent_id:7724

*level:2

type:parent

term:Endogenous

definition:

parent_id:7735

**level:3

type:child

term:Food

definition:

parent_id:7735

**level:3

type:child

term:Biological

definition:A living organism (species or a higher taxonomy rank), in which a chemical can be found.

parent_id:7735

**level:3

type:parent

term:Animal

definition:A living organism belonging to the kingdom animalia. it feeds on organic matter, typically having specialized sense organs and nervous system and able to respond rapidly to stimuli.

parent_id:7736

***level:4

type:child

synonym:Fauna

term:Plant

definition:A living organism belonging to the kingdom plantea. typically, it grows in a permanent site, absorbs water and inorganic substances through its roots, and synthesizes nutrients in its leaves by photosynthesis using the green pigment chlorophyll. examples incude trees, shrubs, herbs, grasses, ferns, and mosses.

parent_id:7736

***level:4

type:parent

synonym:Flora

term:Biological location

definition:The physiological origin within an organism, including anatomical compnents, biofluids and excreta.

parent_id:7724

*level:2

type:parent

term:Tissue and substructures

definition:An anatomical organizational level including multiple cells yet not comprising a complete organ .

parent_id:7725

**level:3

type:parent

term:Placenta

definition:An organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin b. (nci).

parent_id:7729

***level:4

type:child

term:Subcellular

definition:An anatomical organizational level including a component within a biological cell .

parent_id:7725

**level:3

type:parent

term:Golgi

definition:A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. Note that the Golgi apparatus can be located in various places in the cytoplasm.

parent_id:7730

***level:4

type:child

synonym:Golgi apparatus

synonym:Golgi complex

synonym:Golgi ribbon

term:Mitochondria

definition:

parent_id:7730

***level:4

type:child

term:Cytoplasm

definition:The portion of the cell contained within the plasma membrane but excluding the nucleus.

parent_id:7730

***level:4

type:child

synonym:Cytoplasma

term:Organ and components

definition:An anatomical organizational level including multiple tissues or substructures, which enables a common biological function.

parent_id:7725

**level:3

type:parent

term:Brain

definition:An organ composed of grey and white matter that is the center for intelligence and reasoning. it is protected by the bony cranium. (nci).

parent_id:7727

***level:4

type:child

term:Liver

definition:An abdominal organ that has variable lobation which are composed mainly of hepatic lobules. (nci).

parent_id:7727

***level:4

type:child

term:Process

definition:Biological or chemical events, or a series thereof, leading to a known function or end-product.

parent_id:

level:1

type:parent

term:Naturally occurring process

definition:Naturally-occurring molecular events or a series thereof, leading to a known function or end-product.

parent_id:7659

*level:2

type:parent

term:Biological process

definition:Biological or chemical events or a series thereof, leading to a known function or end-product within an organism.

parent_id:7660

**level:3

type:parent

term:Biochemical pathway

definition:A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.

parent_id:7661

***level:4

type:parent

term:Role

definition:The purpose or function assumed by a chemical, either naturally or as intended by humans .

parent_id:

level:1

type:parent

term:Industrial application

definition:The assumed function of a chemical utilized by human.

parent_id:7671

*level:2

type:parent

term:Pharmaceutical industry

definition:A pharmacologic activity for which a chemical substance is utilized owing to its biological role.

parent_id:7678

**level:3

type:parent

term:Pharmaceutical

definition:

parent_id:7679

***level:4

type:child

状态
Solid
实验性质
1:

kind:water_solubility

value:614.5 mg/mL

source:

预测性质
1:

kind:logp

value:-1.63

source:ALOGPS

2:

kind:logs

value:-2.11

source:ALOGPS

3:

kind:solubility

value:3.33 g/L

source:ALOGPS

4:

kind:logp

value:-4.8

source:ChemAxon

5:

kind:pka_strongest_acidic

value:0.7

source:ChemAxon

6:

kind:pka_strongest_basic

value:3.92

source:ChemAxon

7:

kind:iupac

value:{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid

source:ChemAxon

8:

kind:average_mass

value:427.2011

source:ChemAxon

9:

kind:mono_mass

value:427.029414749

source:ChemAxon

10:

kind:smiles

value:NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H]3O)C2=NC=N1

source:ChemAxon

11:

kind:formula

value:C10H15N5O10P2

source:ChemAxon

12:

kind:inchi

value:InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(25-27(20,21)22)4(24-10)1-23-26(17,18)19/h2-4,6-7,10,16H,1H2,(H2,11,12,13)(H2,17,18,19)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1

source:ChemAxon

13:

kind:inchikey

value:WHTCPDAXWFLDIH-KQYNXXCUSA-N

source:ChemAxon

14:

kind:polar_surface_area

value:232.6

source:ChemAxon

15:

kind:refractivity

value:84.94

source:ChemAxon

16:

kind:polarizability

value:34.28

source:ChemAxon

17:

kind:rotatable_bond_count

value:6

source:ChemAxon

18:

kind:acceptor_count

value:12

source:ChemAxon

19:

kind:donor_count

value:6

source:ChemAxon

20:

kind:physiological_charge

value:-4

source:ChemAxon

21:

kind:formal_charge

value:0

source:ChemAxon

22:

kind:number_of_rings

value:3

source:ChemAxon

23:

kind:bioavailability

value:No

source:ChemAxon

24:

kind:rule_of_five

value:No

source:ChemAxon

25:

kind:ghose_filter

value:No

source:ChemAxon

26:

kind:veber_rule

value:No

source:ChemAxon

27:

kind:mddr_like_rule

value:Yes

source:ChemAxon

1:

type:Specdb::CMs

spectrum_id:23135

2:

type:Specdb::CMs

spectrum_id:37273

3:

type:Specdb::CMs

spectrum_id:148305

4:

type:Specdb::NmrTwoD

spectrum_id:1119

5:

type:Specdb::NmrOneD

spectrum_id:1061

6:

type:Specdb::NmrOneD

spectrum_id:5512

7:

type:Specdb::NmrOneD

spectrum_id:5513

8:

type:Specdb::NmrOneD

spectrum_id:5514

9:

type:Specdb::NmrOneD

spectrum_id:5515

10:

type:Specdb::NmrOneD

spectrum_id:5516

11:

type:Specdb::NmrOneD

spectrum_id:5517

12:

type:Specdb::NmrOneD

spectrum_id:5518

13:

type:Specdb::NmrOneD

spectrum_id:5519

14:

type:Specdb::NmrOneD

spectrum_id:5520

15:

type:Specdb::NmrOneD

spectrum_id:5521

16:

type:Specdb::NmrOneD

spectrum_id:5522

17:

type:Specdb::NmrOneD

spectrum_id:5523

18:

type:Specdb::NmrOneD

spectrum_id:5524

19:

type:Specdb::NmrOneD

spectrum_id:5525

20:

type:Specdb::NmrOneD

spectrum_id:5526

21:

type:Specdb::NmrOneD

spectrum_id:5527

22:

type:Specdb::NmrOneD

spectrum_id:5528

23:

type:Specdb::NmrOneD

spectrum_id:5529

24:

type:Specdb::NmrOneD

spectrum_id:5530

25:

type:Specdb::NmrOneD

spectrum_id:5531

26:

type:Specdb::MsMs

spectrum_id:23804

27:

type:Specdb::MsMs

spectrum_id:23805

28:

type:Specdb::MsMs

spectrum_id:23806

29:

type:Specdb::MsMs

spectrum_id:30602

30:

type:Specdb::MsMs

spectrum_id:30603

31:

type:Specdb::MsMs

spectrum_id:30604

32:

type:Specdb::MsMs

spectrum_id:1470897

33:

type:Specdb::MsMs

spectrum_id:1470898

34:

type:Specdb::MsMs

spectrum_id:1470899

35:

type:Specdb::MsMs

spectrum_id:2228122

36:

type:Specdb::MsMs

spectrum_id:2228937

37:

type:Specdb::MsMs

spectrum_id:2230522

38:

type:Specdb::MsMs

spectrum_id:2231241

39:

type:Specdb::MsMs

spectrum_id:2232938

40:

type:Specdb::MsMs

spectrum_id:2233686

41:

type:Specdb::MsMs

spectrum_id:2235277

42:

type:Specdb::MsMs

spectrum_id:2258593

43:

type:Specdb::MsMs

spectrum_id:2396247

44:

type:Specdb::MsMs

spectrum_id:2396248

45:

type:Specdb::MsMs

spectrum_id:2396249

46:

type:Specdb::MsMs

spectrum_id:2539832

47:

type:Specdb::MsMs

spectrum_id:2539833

48:

type:Specdb::MsMs

spectrum_id:2539834

光谱
生物学性质
1:

cellular:(1):Golgi apparatus

2:

biospecimen:(1):Cellular Cytoplasm

3:

tissue:(1):Brain

tissue:(2):Liver

tissue:(3):Placenta

4:

[1]:

name:17-Beta Hydroxysteroid Dehydrogenase III Deficiency

smpdb_id:SMP00356

kegg_map_id:

[2]:

name:Acetaminophen Metabolism Pathway

smpdb_id:SMP00640

kegg_map_id:

[3]:

name:Androgen and Estrogen Metabolism

smpdb_id:SMP00068

kegg_map_id:map00150

[4]:

name:Aromatase deficiency

smpdb_id:SMP00565

kegg_map_id:

[5]:

name:Estrone Metabolism

smpdb_id:SMP30880

kegg_map_id:

[6]:

name:Fabry disease

smpdb_id:SMP00525

kegg_map_id:

[7]:

name:Gaucher Disease

smpdb_id:SMP00349

kegg_map_id:

[8]:

name:Globoid Cell Leukodystrophy

smpdb_id:SMP00348

kegg_map_id:

[9]:

name:Krabbe disease

smpdb_id:SMP00526

kegg_map_id:

[10]:

name:Metachromatic Leukodystrophy (MLD)

smpdb_id:SMP00347

kegg_map_id:

[11]:

name:Starch and sucrose metabolism

smpdb_id:

kegg_map_id:map00500

[12]:

name:Sulfite oxidase deficiency

smpdb_id:SMP00532

kegg_map_id:

[13]:

name:Sulfur metabolism

smpdb_id:

kegg_map_id:map00920

[14]:

name:Tamoxifen Action Pathway

smpdb_id:SMP00471

kegg_map_id:

[15]:

name:Tamoxifen Metabolism Pathway

smpdb_id:SMP00606

kegg_map_id:

正常浓度
1:

biospecimen:Cellular Cytoplasm

concentration_value:137

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

异常浓度
疾病参考
KEGG数据库编号
C00054
DrugBank数据库编号
DB01812
foodb数据库编号
FDB030650
ChemSpider数据库编号
140102
公共化学化合物编号
159296
PDB数据库编号
生物利益的化学实体数据库编号
17985
knapsack数据库编号
C00019352
维基百科编号
代谢途径的数据库编号
3-5-ADP
苯酚资源管理器化合物数据库编号
比格数据库编号
33684
梅林编号
虚拟机身份证编号
PAP
fbonto数据库编号
综合参考
Tsunako, Mitsutomo; Kotone, Akira. Preparation of nucleoside-2',5'- and 3',5'-diphosphoric acids. Jpn. Kokai Tokkyo Koho (1991), 13 pp.
一般参考
1:

protein_accession:HMDBP00119

name:Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

uniprot_id:P22413

gene_name:ENPP1

protein_type:Unknown

2:

protein_accession:HMDBP00194

name:Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

uniprot_id:O14638

gene_name:ENPP3

protein_type:Unknown

3:

protein_accession:HMDBP00286

name:Carbohydrate sulfotransferase 11

uniprot_id:Q9NPF2

gene_name:CHST11

protein_type:Enzyme

4:

protein_accession:HMDBP00287

name:Carbohydrate sulfotransferase 3

uniprot_id:Q7LGC8

gene_name:CHST3

protein_type:Enzyme

5:

protein_accession:HMDBP00288

name:Carbohydrate sulfotransferase 13

uniprot_id:Q8NET6

gene_name:CHST13

protein_type:Enzyme

6:

protein_accession:HMDBP00289

name:Carbohydrate sulfotransferase 12

uniprot_id:Q9NRB3

gene_name:CHST12

protein_type:Enzyme

7:

protein_accession:HMDBP00318

name:Galactosylceramide sulfotransferase

uniprot_id:Q99999

gene_name:GAL3ST1

protein_type:Enzyme

8:

protein_accession:HMDBP00339

name:Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

uniprot_id:Q9Y662

gene_name:HS3ST3B1

protein_type:Enzyme

9:

protein_accession:HMDBP00340

name:Heparan sulfate glucosamine 3-O-sulfotransferase 3A1

uniprot_id:Q9Y663

gene_name:HS3ST3A1

protein_type:Enzyme

10:

protein_accession:HMDBP00341

name:Sulfotransferase 1A1

uniprot_id:P50225

gene_name:SULT1A1

protein_type:Enzyme

11:

protein_accession:HMDBP00342

name:3'(2'),5'-bisphosphate nucleotidase 1

uniprot_id:O95861

gene_name:BPNT1

protein_type:Unknown

12:

protein_accession:HMDBP00343

name:Heparan sulfate glucosamine 3-O-sulfotransferase 1

uniprot_id:O14792

gene_name:HS3ST1

protein_type:Enzyme

13:

protein_accession:HMDBP00346

name:Estrogen sulfotransferase

uniprot_id:P49888

gene_name:SULT1E1

protein_type:Enzyme

14:

protein_accession:HMDBP00347

name:Bile salt sulfotransferase

uniprot_id:Q06520

gene_name:SULT2A1

protein_type:Enzyme

15:

protein_accession:HMDBP00348

name:Carbohydrate sulfotransferase 1

uniprot_id:O43916

gene_name:CHST1

protein_type:Enzyme

16:

protein_accession:HMDBP00349

name:Heparan sulfate glucosamine 3-O-sulfotransferase 4

uniprot_id:Q9Y661

gene_name:HS3ST4

protein_type:Enzyme

17:

protein_accession:HMDBP00350

name:Sulfotransferase 1A2

uniprot_id:P50226

gene_name:SULT1A2

protein_type:Enzyme

18:

protein_accession:HMDBP00351

name:Heparan sulfate glucosamine 3-O-sulfotransferase 5

uniprot_id:Q8IZT8

gene_name:HS3ST5

protein_type:Enzyme

19:

protein_accession:HMDBP00352

name:Heparan sulfate glucosamine 3-O-sulfotransferase 2

uniprot_id:Q9Y278

gene_name:HS3ST2

protein_type:Enzyme

20:

protein_accession:HMDBP00354

name:Protein-tyrosine sulfotransferase 2

uniprot_id:O60704

gene_name:TPST2

protein_type:Enzyme

21:

protein_accession:HMDBP00355

name:Sulfotransferase family cytosolic 2B member 1

uniprot_id:O00204

gene_name:SULT2B1

protein_type:Enzyme

22:

protein_accession:HMDBP00356

name:Sulfotransferase 1A3/1A4

uniprot_id:P50224

gene_name:SULT1A3

protein_type:Enzyme

23:

protein_accession:HMDBP00715

name:Carbohydrate sulfotransferase 7

uniprot_id:Q9NS84

gene_name:CHST7

protein_type:Enzyme

24:

protein_accession:HMDBP02568

name:Carbohydrate sulfotransferase 14

uniprot_id:Q8NCH0

gene_name:CHST14

protein_type:Enzyme

25:

protein_accession:HMDBP02991

name:Heparan-sulfate 6-O-sulfotransferase 1

uniprot_id:O60243

gene_name:HS6ST1

protein_type:Enzyme

26:

protein_accession:HMDBP03073

name:Heparan-sulfate 6-O-sulfotransferase 2

uniprot_id:Q96MM7

gene_name:HS6ST2

protein_type:Enzyme

27:

protein_accession:HMDBP03301

name:Heparan-sulfate 6-O-sulfotransferase 3

uniprot_id:Q8IZP7

gene_name:HS6ST3

protein_type:Enzyme

28:

protein_accession:HMDBP07252

name:Carbohydrate sulfotransferase 15

uniprot_id:Q7LFX5

gene_name:CHST15

protein_type:Enzyme

29:

protein_accession:HMDBP08732

name:Inositol monophosphatase 3

uniprot_id:Q9NX62

gene_name:IMPAD1

protein_type:Unknown

30:

protein_accession:HMDBP09340

name:Tyrosylprotein sulfotransferase 1

uniprot_id:A4D2M0

gene_name:TPST1

protein_type:Enzyme

31:

protein_accession:HMDBP11565

name:L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

uniprot_id:Q9NRN7

gene_name:AASDHPPT

protein_type:Enzyme

32:

protein_accession:HMDBP11788

name:Heparan sulfate glucosamine 3-O-sulfotransferase 6

uniprot_id:Q96QI5

gene_name:HS3ST6

protein_type:Unknown

33:

protein_accession:HMDBP11853

name:Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

uniprot_id:P52848

gene_name:NDST1

protein_type:Unknown

34:

protein_accession:HMDBP11854

name:Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

uniprot_id:P52849

gene_name:NDST2

protein_type:Unknown

35:

protein_accession:HMDBP11855

name:Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

uniprot_id:O95803

gene_name:NDST3

protein_type:Unknown

36:

protein_accession:HMDBP11856

name:Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4

uniprot_id:Q9H3R1

gene_name:NDST4

protein_type:Unknown

37:

protein_accession:HMDBP11965

name:Sulfotransferase 1C3

uniprot_id:Q6IMI6

gene_name:SULT1C3

protein_type:Unknown

38:

protein_accession:HMDBP11966

name:Sulfotransferase 6B1

uniprot_id:Q6IMI4

gene_name:SULT6B1

protein_type:Unknown

39:

protein_accession:HMDBP11981

name:Protein-tyrosine sulfotransferase 1

uniprot_id:O60507

gene_name:TPST1

protein_type:Unknown

蛋白质结合
1:

reference_text:Gasmi L, McLennan AG: The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives. Biochem J. 2001 Jul 1;357(Pt 1):33-8.

pubmed_id:11415433

2:

reference_text:Lewis AJ, Otake Y, Walle UK, Walle T: Sulphonation of N-hydroxy-2-acetylaminofluorene by human dehydroepiandrosterone sulphotransferase. Xenobiotica. 2000 Mar;30(3):253-61.

pubmed_id:10752640

3:

reference_text:Leonidas DD, Chavali GB, Oikonomakos NG, Chrysina ED, Kosmopoulou MN, Vlassi M, Frankling C, Acharya KR: High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors. Protein Sci. 2003 Nov;12(11):2559-74.

pubmed_id:14573867

4:

reference_text:Turner NA, Moake JL, McIntire LV: Blockade of adenosine diphosphate receptors P2Y(12) and P2Y(1) is required to inhibit platelet aggregation in whole blood under flow. Blood. 2001 Dec 1;98(12):3340-5.

pubmed_id:11719372

5:

reference_text:Traut TW: Physiological concentrations of purines and pyrimidines. Mol Cell Biochem. 1994 Nov 9;140(1):1-22.

pubmed_id:7877593

6:

reference_text:Russo N, Acharya KR, Vallee BL, Shapiro R: A combined kinetic and modeling study of the catalytic center subsites of human angiogenin. Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):804-8.

pubmed_id:8570639

7:

reference_text:Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043.

pubmed_id:32033212

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