人类代谢组数据库

版本

5.0

创建日期

2005-11-16 15:48:42 UTC

更新日期

2021-09-14 15:47:19 UTC

登录号

HMDB0000045

地位

quantified

二级访问

HMDB00045

名称

Adenosine monophosphate

描述

Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP can be produced during ATP synthesis by the enzyme adenylate kinase. AMP has recently been approved as a 'Bitter Blocker' additive to foodstuffs. When AMP is added to bitter foods or foods with a bitter aftertaste it makes them seem 'sweeter'. This potentially makes lower calorie food products more palatable.

同义词

1:5'-Adenosine monophosphate

2:5'-Adenylic acid

3:5'-AMP

4:5'-O-Phosphonoadenosine

5:Adenosine 5'-(dihydrogen phosphate)

6:Adenosine 5'-phosphate

7:Adenosine phosphate

8:Adenosine-5'-monophosphoric acid

9:Adenosine-5'p

10:Adenosini phosphas

11:Adenylate

12:Adenylic acid

13:Ado5'p

14:AMP

15:Fosfato de adenosina

16:pA

17:PAdo

18:Phosphate d'adenosine

19:Adenosine 5'-monophosphate

20:Adenyl

21:5'-Adenosine monophosphoric acid

22:5'-Adenylate

23:Adenosine 5'-(dihydrogen phosphoric acid)

24:Adenosine 5'-phosphoric acid

25:Adenosine phosphoric acid

26:Adenosine-5'-monophosphate

27:Phosphoric acid d'adenosine

28:Adenosine 5'-monophosphoric acid

29:Adenosine monophosphoric acid

30:Adenosine 5'-phosphorate

31:Adenosine-5'-monophosphorate

32:Adenosine-5-monophosphorate

33:Adenosine-5-monophosphoric acid

34:Adenosine-monophosphate

35:Adenosine-phosphate

36:Adenovite

37:Cardiomone

38:Lycedan

39:Muscle adenylate

40:Muscle adenylic acid

41:My-b-den

42:My-beta-den

43:Phosaden

44:Phosphaden

45:Phosphentaside

46:5'-Phosphate, adenosine

47:Acid, 2'-adenylic

48:2'-Adenylic acid

49:Adenosine 3' phosphate

50:Disodium, adenosine phosphate

51:Phosphate dipotassium, adenosine

52:Adenosine 2'-phosphate

53:Adenosine 5' phosphate

54:Adenosine phosphate dipotassium

55:Dipotassium, adenosine phosphate

56:2' Adenylic acid

57:5' Adenylic acid

58:Acid, 5'-adenylic

59:Adenosine 3'-phosphate

60:monoPhosphate, 2'-adenosine

61:Phosphate disodium, adenosine

62:2' Adenosine monophosphate

63:2'-AMP

64:2'-Adenosine monophosphate

65:Adenosine 2' phosphate

66:Adenosine phosphate disodium

化学式

C10H14N5O7P

平均分子量

347.2212

等位分子量

347.063084339

化学名称

{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

传统名称

adenylate

CAS 登记号

61-19-8

代谢物结构字符串

NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1

inchi标识符

InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

印记键

UDMBCSSLTHHNCD-KQYNXXCUSA-N

分类学

description: belongs to the class of organic compounds known as purine ribonucleoside monophosphates. These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached.

description:Purine ribonucleoside monophosphates

kingdom:Organic compounds

super_class:Nucleosides, nucleotides, and analogues

class:Purine nucleotides

sub_class:Purine ribonucleotides

molecular_framework:Aromatic heteropolycyclic compounds

1:1,2-diols

2:6-aminopurines

3:Aminopyrimidines and derivatives

4:Azacyclic compounds

5:Glycosylamines

6:Heteroaromatic compounds

7:Hydrocarbon derivatives

8:Imidolactams

9:Monoalkyl phosphates

10:Monosaccharide phosphates

11:N-substituted imidazoles

12:Organic oxides

13:Organopnictogen compounds

14:Oxacyclic compounds

15:Pentose phosphates

16:Primary amines

17:Secondary alcohols

18:Tetrahydrofurans

19:1,2-diol

20:6-aminopurine

21:Alcohol

22:Alkyl phosphate

23:Amine

24:Aminopyrimidine

25:Aromatic heteropolycyclic compound

26:Azacycle

27:Azole

28:Glycosyl compound

29:Heteroaromatic compound

30:Hydrocarbon derivative

31:Imidazole

32:Imidazopyrimidine

33:Imidolactam

34:Monoalkyl phosphate

35:Monosaccharide

36:Monosaccharide phosphate

37:N-glycosyl compound

38:N-substituted imidazole

39:Organic nitrogen compound

40:Organic oxide

41:Organic oxygen compound

42:Organic phosphoric acid derivative

43:Organoheterocyclic compound

44:Organonitrogen compound

45:Organooxygen compound

46:Organopnictogen compound

47:Oxacycle

48:Pentose monosaccharide

49:Pentose phosphate

50:Pentose-5-phosphate

51:Phosphoric acid ester

52:Primary amine

53:Purine

54:Purine ribonucleoside monophosphate

55:Pyrimidine

56:Secondary alcohol

57:Tetrahydrofuran

58:Ribonucleotides

59:adenosine 5'-phosphate

60:purine ribonucleoside 5'-monophosphate

本体论

term:Physiological effect

definition:The effect on an organism physiology, resulting from its exposure to a chemical.

parent_id:

level:1

type:parent

term:Health effect

definition:A health condition or observation associated with a stimuli or with a biological activity of a chemical.

parent_id:7693

*level:2

type:parent

term:Observation

definition:A short term health effect which reflects the reponse of the body to stimuli or is a symptom of a disease or condition; also includes health status which reflects stage in life.

parent_id:7694

**level:3

type:parent

term:Attachment loss

definition:

parent_id:7717

***level:4

type:child

term:Missing teeth

definition:

parent_id:7717

***level:4

type:child

term:Periodontal Probing Depth

definition:

parent_id:7717

***level:4

type:child

term:Disposition

definition:A concept that describes the origin of a chemical, its location within an organism, or its route of exposure.

parent_id:

level:1

type:parent

term:Source

definition:Natural or synthetic origin of a chemical.

parent_id:7724

*level:2

type:parent

term:Endogenous

definition:

parent_id:7735

**level:3

type:child

term:Biological location

definition:The physiological origin within an organism, including anatomical compnents, biofluids and excreta.

parent_id:7724

*level:2

type:parent

term:Tissue and substructures

definition:An anatomical organizational level including multiple cells yet not comprising a complete organ .

parent_id:7725

**level:3

type:parent

term:All tissues

definition:All tissues in the body of the organism.

parent_id:7729

***level:4

type:child

term:Placenta

definition:An organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin b. (nci).

parent_id:7729

***level:4

type:child

term:Biofluid and excreta

definition:A liquid, semi-solid or solid material originating in the body.

parent_id:7725

**level:3

type:parent

term:Urine

definition:Excretion in liquid state processed by the kidney.

parent_id:7731

***level:4

type:child

term:Saliva

definition:The watery fluid in the mouth made by the salivary glands. saliva moistens food to help digestion and it helps protect the mouth against infections. (nci).

parent_id:7731

***level:4

type:child

term:Feces

definition:The material discharged from the bowel during defecation. It consists of undigested food, intestinal mucus, epithelial cells, and bacteria.

parent_id:7731

***level:4

type:child

synonym:Fecal

synonym:Stool

synonym:Faecal

synonym:Faeces

term:Blood

definition:A liquid tissue with the primary function of transporting oxygen and carbon dioxide (nci). it supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection.

parent_id:7731

***level:4

type:child

term:Cerebrospinal fluid

definition:The fluid that is contained within the brain ventricles, the subarachnoid space and the central canal of the spinal cord. (nci).

parent_id:7731

***level:4

type:child

synonym:Csf

term:Subcellular

definition:An anatomical organizational level including a component within a biological cell .

parent_id:7725

**level:3

type:parent

term:Cytoplasm

definition:The portion of the cell contained within the plasma membrane but excluding the nucleus.

parent_id:7730

***level:4

type:child

synonym:Cytoplasma

term:Mitochondria

definition:

parent_id:7730

***level:4

type:child

term:Nucleus

definition:A body within the cell, surrounded by a membrane, within which lie the chromosomes, one or more nucleoli, combined with proteins, and exhibits mitosis. (NCI)

parent_id:7730

***level:4

type:child

synonym:Cell nucleus

synonym:Nucleic

term:Lysosome

definition:В A sac-like compartment inside a cell that has enzymes that can break down cellular components that need to be destroyed. (NCI).

parent_id:7730

***level:4

type:child

term:Endoplasmic reticulum

definition:A network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials. (Infoplease Dictionary via NCI)

parent_id:7730

***level:4

type:child

synonym:Er

term:Peroxisome

definition:A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. (Gene Ontology).

parent_id:7730

***level:4

type:child

synonym:Peroxisome vesicle

synonym:Peroxisomal

term:Golgi

definition:A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. Note that the Golgi apparatus can be located in various places in the cytoplasm.

parent_id:7730

***level:4

type:child

synonym:Golgi apparatus

synonym:Golgi complex

synonym:Golgi ribbon

term:Cell and elements

definition:An anatomical organizational level comprising of a single cell (or a fragment in some exceptions). a cell is defined by its type or function. it is the smallest unit of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid.

parent_id:7725

**level:3

type:parent

term:Extracellular

definition:The space external to the outermost structure of a cell.

parent_id:7732

***level:4

type:child

synonym:Extracellular region

term:Process

definition:Biological or chemical events, or a series thereof, leading to a known function or end-product.

parent_id:

level:1

type:parent

term:Naturally occurring process

definition:Naturally-occurring molecular events or a series thereof, leading to a known function or end-product.

parent_id:7659

*level:2

type:parent

term:Biological process

definition:Biological or chemical events or a series thereof, leading to a known function or end-product within an organism.

parent_id:7660

**level:3

type:parent

term:Biochemical pathway

definition:A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.

parent_id:7661

***level:4

type:parent

term:Biochemical process

definition:A biological process occurring at the subcellular level, involving biochemical reactions.

parent_id:7661

***level:4

type:parent

term:Role

definition:The purpose or function assumed by a chemical, either naturally or as intended by humans .

parent_id:

level:1

type:parent

term:Industrial application

definition:The assumed function of a chemical utilized by human.

parent_id:7671

*level:2

type:parent

term:Pharmaceutical industry

definition:A pharmacologic activity for which a chemical substance is utilized owing to its biological role.

parent_id:7678

**level:3

type:parent

term:Pharmaceutical

definition:

parent_id:7679

***level:4

type:child

term:Biological role

definition:The biological function of a chemical. the biological role answers the question how a chemical is involved in molecular processes in an organism. this can include biochemical effects of non-endogenous chemicals, which are also assigned an industrial application such as pharmaceuticals. the biological role is limited to cellular levls, and will not include role at system process level, such as a chemical which has a role in a disease.

parent_id:7671

*level:2

type:parent

term:Drug metabolite

definition:

parent_id:7672

**level:3

type:child

term:Waste product

definition:A chemical that is generated in a metabolic process and is destined to be excreted from the body. It commonly consists of water, nitrogenous compounds or carbon dioxide and can be a metabolic byproduct or a degradation product (such as urobilin metabolised from bilirubin which is a degradation product of hemoglobin).

parent_id:7672

**level:3

type:child

状态

Solid

实验性质

kind:water_solubility

value:10 mg/mL at 20 °C

source:BEILSTEIN

kind:melting_point

value:195 °C

source:

预测性质

kind:logp

value:-3.13

source:ALOGPS

kind:logs

value:-2.02

source:ALOGPS

kind:solubility

value:3.31 g/L

source:ALOGPS

kind:logp

value:-4.7

source:ChemAxon

kind:pka_strongest_acidic

value:1.22

source:ChemAxon

kind:pka_strongest_basic

value:3.92

source:ChemAxon

kind:iupac

value:{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

source:ChemAxon

kind:average_mass

value:347.2212

source:ChemAxon

kind:mono_mass

value:347.063084339

source:ChemAxon

10:

kind:smiles

value:NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1

source:ChemAxon

11:

kind:formula

value:C10H14N5O7P

source:ChemAxon

12:

kind:inchi

value:InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

source:ChemAxon

13:

kind:inchikey

value:UDMBCSSLTHHNCD-KQYNXXCUSA-N

source:ChemAxon

14:

kind:polar_surface_area

value:186.07

source:ChemAxon

15:

kind:refractivity

value:74.07

source:ChemAxon

16:

kind:polarizability

value:29.96

source:ChemAxon

17:

kind:rotatable_bond_count

value:4

source:ChemAxon

18:

kind:acceptor_count

value:10

source:ChemAxon

19:

kind:donor_count

value:5

source:ChemAxon

20:

kind:physiological_charge

value:-2

source:ChemAxon

21:

kind:formal_charge

value:0

source:ChemAxon

22:

kind:number_of_rings

value:3

source:ChemAxon

23:

kind:bioavailability

value:Yes

source:ChemAxon

24:

kind:rule_of_five

value:Yes

source:ChemAxon

25:

kind:ghose_filter

value:No

source:ChemAxon

26:

kind:veber_rule

value:No

source:ChemAxon

27:

kind:mddr_like_rule

value:No

source:ChemAxon

type:Specdb::NmrOneD

spectrum_id:1051

type:Specdb::NmrOneD

spectrum_id:5452

type:Specdb::NmrOneD

spectrum_id:5453

type:Specdb::NmrOneD

spectrum_id:5454

type:Specdb::NmrOneD

spectrum_id:5455

type:Specdb::NmrOneD

spectrum_id:5456

type:Specdb::NmrOneD

spectrum_id:5457

type:Specdb::NmrOneD

spectrum_id:5458

type:Specdb::NmrOneD

spectrum_id:5459

10:

type:Specdb::NmrOneD

spectrum_id:5460

11:

type:Specdb::NmrOneD

spectrum_id:5461

12:

type:Specdb::NmrOneD

spectrum_id:5462

13:

type:Specdb::NmrOneD

spectrum_id:5463

14:

type:Specdb::NmrOneD

spectrum_id:5464

15:

type:Specdb::NmrOneD

spectrum_id:5465

16:

type:Specdb::NmrOneD

spectrum_id:5466

17:

type:Specdb::NmrOneD

spectrum_id:5467

18:

type:Specdb::NmrOneD

spectrum_id:5468

19:

type:Specdb::NmrOneD

spectrum_id:5469

20:

type:Specdb::NmrOneD

spectrum_id:5470

21:

type:Specdb::NmrOneD

spectrum_id:5471

22:

type:Specdb::NmrOneD

spectrum_id:166346

23:

type:Specdb::NmrOneD

spectrum_id:166412

24:

type:Specdb::NmrOneD

spectrum_id:166608

25:

type:Specdb::CMs

spectrum_id:2234

26:

type:Specdb::CMs

spectrum_id:2236

27:

type:Specdb::CMs

spectrum_id:24338

28:

type:Specdb::CMs

spectrum_id:30967

29:

type:Specdb::CMs

spectrum_id:30968

30:

type:Specdb::CMs

spectrum_id:37264

31:

type:Specdb::CMs

spectrum_id:174079

32:

type:Specdb::NmrTwoD

spectrum_id:942

33:

type:Specdb::NmrTwoD

spectrum_id:1109

34:

type:Specdb::MsMs

spectrum_id:6172

35:

type:Specdb::MsMs

spectrum_id:6173

36:

type:Specdb::MsMs

spectrum_id:6174

37:

type:Specdb::MsMs

spectrum_id:6175

38:

type:Specdb::MsMs

spectrum_id:6176

39:

type:Specdb::MsMs

spectrum_id:6177

40:

type:Specdb::MsMs

spectrum_id:6178

41:

type:Specdb::MsMs

spectrum_id:6179

42:

type:Specdb::MsMs

spectrum_id:6180

43:

type:Specdb::MsMs

spectrum_id:6181

44:

type:Specdb::MsMs

spectrum_id:6182

45:

type:Specdb::MsMs

spectrum_id:6183

46:

type:Specdb::MsMs

spectrum_id:6184

47:

type:Specdb::MsMs

spectrum_id:6185

48:

type:Specdb::MsMs

spectrum_id:6186

49:

type:Specdb::MsMs

spectrum_id:6187

50:

type:Specdb::MsMs

spectrum_id:6188

51:

type:Specdb::MsMs

spectrum_id:6189

52:

type:Specdb::MsMs

spectrum_id:6190

53:

type:Specdb::MsMs

spectrum_id:178872

54:

type:Specdb::MsMs

spectrum_id:178873

55:

type:Specdb::MsMs

spectrum_id:178874

56:

type:Specdb::MsMs

spectrum_id:181197

57:

type:Specdb::MsMs

spectrum_id:181198

58:

type:Specdb::MsMs

spectrum_id:181199

光谱

生物学性质

cellular:(1):Cytoplasm

cellular:(2):Endoplasmic reticulum

cellular:(3):Extracellular

cellular:(4):Golgi apparatus

cellular:(5):Lysosome

cellular:(6):Mitochondria

cellular:(7):Nucleus

cellular:(8):Peroxisome

biospecimen:(1):Blood

biospecimen:(2):Cellular Cytoplasm

biospecimen:(3):Cerebrospinal Fluid (CSF)

biospecimen:(4):Feces

biospecimen:(5):Saliva

biospecimen:(6):Urine

tissue:(1):All Tissues

tissue:(2):Placenta

[1]:

name:2-Hydroxyglutric Aciduria (D And L Form)

smpdb_id:SMP00136

kegg_map_id:

[2]:

name:3-Phosphoglycerate dehydrogenase deficiency

smpdb_id:SMP00721

kegg_map_id:

[3]:

name:4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency

smpdb_id:SMP00243

kegg_map_id:

[4]:

name:Abacavir Action Pathway

smpdb_id:SMP00737

kegg_map_id:

[5]:

name:Acylcarnitine (13Z,16Z)-Hexacosa-13,16-dienoylcarnitine

smpdb_id:SMP0123313

kegg_map_id:

[6]:

name:Acylcarnitine (17Z)-Hexacos-17-enoylcarnitine

smpdb_id:SMP0123312

kegg_map_id:

[7]:

name:Acylcarnitine (2S,3R)-3-Hydroxy-2-methylbutanoylcarnitine

smpdb_id:SMP0123317

kegg_map_id:

[8]:

name:Acylcarnitine (7Z,9Z,12Z,15Z,18Z,21Z)-tetracosa-7,9,12,15,18,21-hexaenoylcarnitine

smpdb_id:SMP0123309

kegg_map_id:

[9]:

name:Acylcarnitine 3-Hydroxydecanoylcarnitine

smpdb_id:SMP0123308

kegg_map_id:

[10]:

name:Acylcarnitine Heptacosanoylcarnitine

smpdb_id:SMP0123314

kegg_map_id:

[11]:

name:Acylcarnitine Hexacosanoylcarnitine

smpdb_id:SMP0123311

kegg_map_id:

[12]:

name:Acylcarnitine Nonacosanoylcarnitine

smpdb_id:SMP0123316

kegg_map_id:

[13]:

name:Acylcarnitine Octacosanoylcarnitine

smpdb_id:SMP0123315

kegg_map_id:

[14]:

name:Acylcarnitine Pentacosanoylcarnitine

smpdb_id:SMP0123310

kegg_map_id:

[15]:

name:Adenine phosphoribosyltransferase deficiency (APRT)

smpdb_id:SMP00535

kegg_map_id:

[16]:

name:Adenosine Deaminase Deficiency

smpdb_id:SMP00144

kegg_map_id:

[17]:

name:Adenylosuccinate Lyase Deficiency

smpdb_id:SMP00167

kegg_map_id:

[18]:

name:AICA-Ribosiduria

smpdb_id:SMP00168

kegg_map_id:

[19]:

name:Alanine, aspartate and glutamate metabolism

smpdb_id:

kegg_map_id:map00250

[20]:

name:Amikacin Action Pathway

smpdb_id:SMP00253

kegg_map_id:

[21]:

name:Arbekacin Action Pathway

smpdb_id:SMP00713

kegg_map_id:

[22]:

name:Arginine and proline metabolism

smpdb_id:

kegg_map_id:map00330

[23]:

name:Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)

smpdb_id:SMP00362

kegg_map_id:

[24]:

name:Argininemia

smpdb_id:SMP00357

kegg_map_id:

[25]:

name:Argininosuccinic Aciduria

smpdb_id:SMP00003

kegg_map_id:

[26]:

name:Aspartate Metabolism

smpdb_id:SMP00067

kegg_map_id:map00250

[27]:

name:Azathioprine Action Pathway

smpdb_id:SMP00427

kegg_map_id:

[28]:

name:Azithromycin Action Pathway

smpdb_id:SMP00247

kegg_map_id:

[29]:

name:Beta-mercaptolactate-cysteine disulfiduria

smpdb_id:SMP00499

kegg_map_id:

[30]:

name:Butyrate Metabolism

smpdb_id:SMP00073

kegg_map_id:map00650

[31]:

name:Canavan Disease

smpdb_id:SMP00175

kegg_map_id:

[32]:

name:Carbamoyl Phosphate Synthetase Deficiency

smpdb_id:SMP00002

kegg_map_id:

[33]:

name:Carnitine palmitoyl transferase deficiency (I)

smpdb_id:SMP00538

kegg_map_id:

[34]:

name:Carnitine palmitoyl transferase deficiency (II)

smpdb_id:SMP00541

kegg_map_id:

[35]:

name:Chloramphenicol Action Pathway

smpdb_id:SMP00729

kegg_map_id:

[36]:

name:Citrullinemia Type I

smpdb_id:SMP00001

kegg_map_id:

[37]:

name:Clarithromycin Action Pathway

smpdb_id:SMP00248

kegg_map_id:

[38]:

name:Clindamycin Action Pathway

smpdb_id:SMP00249

kegg_map_id:

[39]:

name:Clomocycline Action Pathway

smpdb_id:SMP00262

kegg_map_id:

[40]:

name:Creatine deficiency, guanidinoacetate methyltransferase deficiency

smpdb_id:SMP00504

kegg_map_id:

[41]:

name:Cystathionine Beta-Synthase Deficiency

smpdb_id:SMP00177

kegg_map_id:

[42]:

name:Cysteine Metabolism

smpdb_id:SMP00013

kegg_map_id:map00270

[43]:

name:Cystinosis, ocular nonnephropathic

smpdb_id:SMP00722

kegg_map_id:

[44]:

name:Delavirdine Action Pathway

smpdb_id:SMP00738

kegg_map_id:

[45]:

name:Demeclocycline Action Pathway

smpdb_id:SMP00290

kegg_map_id:

[46]:

name:Didanosine Action Pathway

smpdb_id:SMP00739

kegg_map_id:

[47]:

name:Dihydropyrimidine Dehydrogenase Deficiency (DHPD)

smpdb_id:SMP00179

kegg_map_id:

[48]:

name:Dimethylglycine Dehydrogenase Deficiency

smpdb_id:SMP00242

kegg_map_id:

[49]:

name:Dimethylglycine Dehydrogenase Deficiency

smpdb_id:SMP00484

kegg_map_id:

[50]:

name:Disulfiram Action Pathway

smpdb_id:SMP00429

kegg_map_id:

[51]:

name:Doxycycline Action Pathway

smpdb_id:SMP00291

kegg_map_id:

[52]:

name:Efavirenz Action Pathway

smpdb_id:SMP00740

kegg_map_id:

[53]:

name:Emtricitabine Action Pathway

smpdb_id:SMP00741

kegg_map_id:

[54]:

name:Erythromycin Action Pathway

smpdb_id:SMP00250

kegg_map_id:

[55]:

name:Ethanol Degradation

smpdb_id:SMP00449

kegg_map_id:

[56]:

name:Ethylmalonic Encephalopathy

smpdb_id:SMP00181

kegg_map_id:

[57]:

name:Fatty acid Metabolism

smpdb_id:SMP00051

kegg_map_id:map00071

[58]:

name:Gentamicin Action Pathway

smpdb_id:SMP00254

kegg_map_id:

[59]:

name:Glucose-6-phosphate dehydrogenase deficiency

smpdb_id:SMP00518

kegg_map_id:

[60]:

name:Glutamate Metabolism

smpdb_id:SMP00072

kegg_map_id:map00250

[61]:

name:Glutaric Aciduria Type I

smpdb_id:SMP00185

kegg_map_id:

[62]:

name:Glycine N-methyltransferase Deficiency

smpdb_id:SMP00222

kegg_map_id:

[63]:

name:Glycine, serine and threonine metabolism

smpdb_id:

kegg_map_id:map00260

[64]:

name:Gout or Kelley-Seegmiller Syndrome

smpdb_id:SMP00365

kegg_map_id:

[65]:

name:Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)

smpdb_id:SMP00188

kegg_map_id:

[66]:

name:Histidine metabolism

smpdb_id:SMP00044

kegg_map_id:map00340

[67]:

name:Histidinemia

smpdb_id:SMP00191

kegg_map_id:

[68]:

name:Homocarnosinosis

smpdb_id:SMP00385

kegg_map_id:

[69]:

name:Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation type

smpdb_id:SMP00570

kegg_map_id:

[70]:

name:Hyperglycinemia, non-ketotic

smpdb_id:SMP00485

kegg_map_id:

[71]:

name:Hyperinsulinism-Hyperammonemia Syndrome

smpdb_id:SMP00339

kegg_map_id:

[72]:

name:Hypermethioninemia

smpdb_id:SMP00341

kegg_map_id:

[73]:

name:Hyperornithinemia with gyrate atrophy (HOGA)

smpdb_id:SMP00505

kegg_map_id:

[74]:

name:Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]

smpdb_id:SMP00506

kegg_map_id:

[75]:

name:Hyperprolinemia Type I

smpdb_id:SMP00361

kegg_map_id:

[76]:

name:Hyperprolinemia Type II

smpdb_id:SMP00360

kegg_map_id:

[77]:

name:Hypoacetylaspartia

smpdb_id:SMP00192

kegg_map_id:

[78]:

name:Josamycin Action Pathway

smpdb_id:SMP00731

kegg_map_id:

[79]:

name:Kanamycin Action Pathway

smpdb_id:SMP00255

kegg_map_id:

[80]:

name:L-arginine:glycine amidinotransferase deficiency

smpdb_id:SMP00507

kegg_map_id:

[81]:

name:Lactic Acidemia

smpdb_id:SMP00313

kegg_map_id:

[82]:

name:Lamivudine Action Pathway

smpdb_id:SMP00742

kegg_map_id:

[83]:

name:Leigh Syndrome

smpdb_id:SMP00196

kegg_map_id:

[84]:

name:Lesch-Nyhan Syndrome (LNS)

smpdb_id:SMP00364

kegg_map_id:

[85]:

name:Lincomycin Action Pathway

smpdb_id:SMP00728

kegg_map_id:

[86]:

name:Long chain acyl-CoA dehydrogenase deficiency (LCAD)

smpdb_id:SMP00539

kegg_map_id:

[87]:

name:Lymecycline Action Pathway

smpdb_id:SMP00295

kegg_map_id:

[88]:

name:Malonic Aciduria

smpdb_id:SMP00198

kegg_map_id:

[89]:

name:Malonyl-coa decarboxylase deficiency

smpdb_id:SMP00502

kegg_map_id:

[90]:

name:Medium chain acyl-coa dehydrogenase deficiency (MCAD)

smpdb_id:SMP00542

kegg_map_id:

[91]:

name:Mercaptopurine Action Pathway

smpdb_id:SMP00428

kegg_map_id:

[92]:

name:Mercaptopurine Metabolism Pathway

smpdb_id:SMP00609

kegg_map_id:

[93]:

name:Methacycline Action Pathway

smpdb_id:SMP00727

kegg_map_id:

[94]:

name:Methionine Adenosyltransferase Deficiency

smpdb_id:SMP00221

kegg_map_id:

[95]:

name:Methionine Metabolism

smpdb_id:SMP00033

kegg_map_id:map00270

[96]:

name:Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)

smpdb_id:SMP00340

kegg_map_id:

[97]:

name:Methylmalonic Aciduria Due to Cobalamin-Related Disorders

smpdb_id:SMP00201

kegg_map_id:

[98]:

name:Minocycline Action Pathway

smpdb_id:SMP00292

kegg_map_id:

[99]:

name:Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids

smpdb_id:SMP00482

kegg_map_id:

[100]:

name:Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids

smpdb_id:SMP00481

kegg_map_id:

[101]:

name:Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids

smpdb_id:SMP00480

kegg_map_id:

[102]:

name:Mitochondrial DNA depletion syndrome

smpdb_id:SMP00536

kegg_map_id:

[103]:

name:Molybdenum Cofactor Deficiency

smpdb_id:SMP00203

kegg_map_id:

[104]:

name:Myoadenylate deaminase deficiency

smpdb_id:SMP00537

kegg_map_id:

[105]:

name:Neomycin Action Pathway

smpdb_id:SMP00256

kegg_map_id:

[106]:

name:Netilmicin Action Pathway

smpdb_id:SMP00257

kegg_map_id:

[107]:

name:Nevirapine Action Pathway

smpdb_id:SMP00743

kegg_map_id:

[108]:

name:Nicotinate and nicotinamide metabolism

smpdb_id:

kegg_map_id:map00760

[109]:

name:Nitrogen metabolism

smpdb_id:

kegg_map_id:map00910

[110]:

name:Non Ketotic Hyperglycinemia

smpdb_id:SMP00223

kegg_map_id:

[111]:

name:Ornithine Aminotransferase Deficiency (OAT Deficiency)

smpdb_id:SMP00363

kegg_map_id:

[112]:

name:Ornithine Transcarbamylase Deficiency (OTC Deficiency)

smpdb_id:SMP00205

kegg_map_id:

[113]:

name:Oxytetracycline Action Pathway

smpdb_id:SMP00293

kegg_map_id:

[114]:

name:Pantothenate and CoA Biosynthesis

smpdb_id:SMP00027

kegg_map_id:map00770

[115]:

name:Paromomycin Action Pathway

smpdb_id:SMP00714

kegg_map_id:

[116]:

name:pentose phosphate pathway

smpdb_id:

kegg_map_id:

[117]:

name:Phenylalanine and Tyrosine Metabolism

smpdb_id:SMP00008

kegg_map_id:map00360

[118]:

name:Phenylalanine metabolism

smpdb_id:

kegg_map_id:map00360

[119]:

name:Phenylketonuria

smpdb_id:SMP00206

kegg_map_id:

[120]:

name:Primary hyperoxaluria II, PH2

smpdb_id:SMP00558

kegg_map_id:

[121]:

name:Primary Hyperoxaluria Type I

smpdb_id:SMP00352

kegg_map_id:

[122]:

name:Prolidase Deficiency (PD)

smpdb_id:SMP00207

kegg_map_id:

[123]:

name:Prolinemia Type II

smpdb_id:SMP00208

kegg_map_id:

[124]:

name:Propanoate metabolism

smpdb_id:

kegg_map_id:map00640

[125]:

name:Purine metabolism

smpdb_id:

kegg_map_id:map00230

[126]:

name:Purine Nucleoside Phosphorylase Deficiency

smpdb_id:SMP00210

kegg_map_id:

[127]:

name:Pyruvate Carboxylase Deficiency

smpdb_id:SMP00350

kegg_map_id:

[128]:

name:Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)

smpdb_id:SMP00334

kegg_map_id:

[129]:

name:Pyruvate Dehydrogenase Complex Deficiency

smpdb_id:SMP00212

kegg_map_id:

[130]:

name:Pyruvate kinase deficiency

smpdb_id:SMP00559

kegg_map_id:

[131]:

name:Pyruvate metabolism

smpdb_id:

kegg_map_id:map00620

[132]:

name:Riboflavin Metabolism

smpdb_id:SMP00070

kegg_map_id:map00740

[133]:

name:Ribose-5-phosphate isomerase deficiency

smpdb_id:SMP00519

kegg_map_id:

[134]:

name:Rilpivirine Action Pathway

smpdb_id:SMP00744

kegg_map_id:

[135]:

name:Rolitetracycline Action Pathway

smpdb_id:SMP00726

kegg_map_id:

[136]:

name:Roxithromycin Action Pathway

smpdb_id:SMP00251

kegg_map_id:

[137]:

name:S-Adenosylhomocysteine (SAH) Hydrolase Deficiency

smpdb_id:SMP00214

kegg_map_id:

[138]:

name:Sarcosinemia

smpdb_id:SMP00244

kegg_map_id:

[139]:

name:Selenocompound metabolism

smpdb_id:

kegg_map_id:map00450

[140]:

name:Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)

smpdb_id:SMP00235

kegg_map_id:

[141]:

name:Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (SCHAD)

smpdb_id:SMP00568

kegg_map_id:

[142]:

name:Spectinomycin Action Pathway

smpdb_id:SMP00258

kegg_map_id:

[143]:

name:Stavudine Action Pathway

smpdb_id:SMP00745

kegg_map_id:

[144]:

name:Streptomycin Action Pathway

smpdb_id:SMP00259

kegg_map_id:

[145]:

name:Succinic semialdehyde dehydrogenase deficiency

smpdb_id:SMP00567

kegg_map_id:

[146]:

name:Telithromycin Action Pathway

smpdb_id:SMP00252

kegg_map_id:

[147]:

name:Tetracycline Action Pathway

smpdb_id:SMP00294

kegg_map_id:

[148]:

name:Thiamine Metabolism

smpdb_id:SMP00076

kegg_map_id:map00730

[149]:

name:Thioguanine Action Pathway

smpdb_id:SMP00430

kegg_map_id:

[150]:

name:Tigecycline Action Pathway

smpdb_id:SMP00712

kegg_map_id:

[151]:

name:Tobramycin Action Pathway

smpdb_id:SMP00711

kegg_map_id:

[152]:

name:Transaldolase deficiency

smpdb_id:SMP00520

kegg_map_id:

[153]:

name:Transcription/Translation

smpdb_id:SMP00019

kegg_map_id:

[154]:

name:Trifunctional protein deficiency

smpdb_id:SMP00545

kegg_map_id:

[155]:

name:Troleandomycin Action Pathway

smpdb_id:SMP00730

kegg_map_id:

[156]:

name:Tyrosinemia Type 2 (or Richner-Hanhart syndrome)

smpdb_id:SMP00369

kegg_map_id:

[157]:

name:Tyrosinemia Type 3 (TYRO3)

smpdb_id:SMP00370

kegg_map_id:

[158]:

name:Urea Cycle

smpdb_id:SMP00059

kegg_map_id:map00330

[159]:

name:Valproic Acid Metabolism Pathway

smpdb_id:SMP00635

kegg_map_id:

[160]:

name:Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)

smpdb_id:SMP00540

kegg_map_id:

[161]:

name:Xanthine Dehydrogenase Deficiency (Xanthinuria)

smpdb_id:SMP00220

kegg_map_id:

[162]:

name:Xanthinuria type I

smpdb_id:SMP00512

kegg_map_id:

[163]:

name:Xanthinuria type II

smpdb_id:SMP00513

kegg_map_id:

[164]:

name:Zalcitabine Action Pathway

smpdb_id:SMP00746

kegg_map_id:

[165]:

name:Zidovudine Action Pathway

smpdb_id:SMP00747

kegg_map_id:

正常浓度

biospecimen:Blood

concentration_value:5.1+/- 1.3

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Female

subject_condition:Normal

biospecimen:Blood

concentration_value:51.0 (10.0-92.0)

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

biospecimen:Blood

concentration_value:14.0 +/- 3.0

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Male

subject_condition:Normal

biospecimen:Blood

concentration_value:6.2 +/- 3.1

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Male

subject_condition:Normal

biospecimen:Cellular Cytoplasm

concentration_value:80.0 (71.0-89.0)

concentration_units:uM

subject_age:Children (1-13 years old)

subject_sex:Both

subject_condition:Normal

biospecimen:Cellular Cytoplasm

concentration_value:23

concentration_units:uM

subject_age:Children (1-13 years old)

subject_sex:Both

subject_condition:Normal

biospecimen:Cerebrospinal Fluid (CSF)

concentration_value:< 0.2

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

10:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

11:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Children (6 - 18 years old)

subject_sex:Not Specified

subject_condition:Normal

12:

biospecimen:Saliva

concentration_value:0.793 +/- 0.705

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Not Specified

subject_condition:Normal

13:

biospecimen:Saliva

concentration_value:3.70 +/- 3.32

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Female

subject_condition:Normal

14:

biospecimen:Saliva

concentration_value:0.912 +/- 0.994

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

15:

biospecimen:Saliva

concentration_value:1.04 +/- 1.08

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Female

subject_condition:Normal

16:

biospecimen:Saliva

concentration_value:1.19 +/- 2.66

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Female

subject_condition:Normal

17:

biospecimen:Saliva

concentration_value:1.51 +/- 1.44

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Not Specified

subject_condition:Normal

18:

biospecimen:Saliva

concentration_value:1.60 +/- 1.12

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

19:

biospecimen:Saliva

concentration_value:0.124 +/- 0.284

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Male

subject_condition:Normal

20:

biospecimen:Saliva

concentration_value:0.30 +/- 0.14

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

21:

biospecimen:Saliva

concentration_value:0.99 +/- 0.16

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

22:

biospecimen:Saliva

concentration_value:1.24 +/- 0.33

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

23:

biospecimen:Saliva

concentration_value:1.10 +/- 0.29

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

24:

biospecimen:Saliva

concentration_value:0.321 +/- 0.506

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Female

subject_condition:Normal

25:

biospecimen:Urine

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Male

subject_condition:Normal

异常浓度

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Metastatic melanoma

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Colorectal cancer

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Children (6 - 18 years old)

patient_sex:Not Specified

patient_information:Crohns disease

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Children (6 - 18 years old)

patient_sex:Not Specified

patient_information:Ulcerative colitis

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Children (6 - 18 years old)

patient_sex:Not Specified

patient_information:Unclassified IBD

biospecimen:Saliva

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Male

patient_information:Attachment loss

biospecimen:Saliva

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Male

patient_information:Missing teeth

biospecimen:Saliva

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Male

patient_information:Periodontal Probing Depth

biospecimen:Saliva

concentration_value:1.39 +/- 1.25

concentration_units:uM

patient_age:Adult (>18 years old)

patient_sex:Male

patient_information:Alzheimer's disease

10:

biospecimen:Saliva

concentration_value:3.72 +/- 4.53

concentration_units:uM

patient_age:Adult (>18 years old)

patient_sex:Male

patient_information:Frontotemporal lobe dementia

11:

biospecimen:Saliva

concentration_value:4.12 +/- 6.43

concentration_units:uM

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Lewy body disease

疾病参考

name:Crohn's disease

omim_id:266600

[1]:

reference_text:Lapidus A, Akerlund JE, Einarsson C: Gallbladder bile composition in patients with Crohn 's disease. World J Gastroenterol. 2006 Jan 7;12(1):70-4.

pubmed_id:16440420

[2]:

reference_text:Ehrenpreis ED, Salvino M, Craig RM: Improving the serum D-xylose test for the identification of patients with small intestinal malabsorption. J Clin Gastroenterol. 2001 Jul;33(1):36-40.

pubmed_id:11418788

[3]:

reference_text:Brydon WG, Nyhlin H, Eastwood MA, Merrick MV: Serum 7 alpha-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea. Eur J Gastroenterol Hepatol. 1996 Feb;8(2):117-23.

pubmed_id:8723414

[4]:

reference_text:Williams HR, Cox IJ, Walker DG, North BV, Patel VM, Marshall SE, Jewell DP, Ghosh S, Thomas HJ, Teare JP, Jakobovits S, Zeki S, Welsh KI, Taylor-Robinson SD, Orchard TR: Characterization of inflammatory bowel disease with urinary metabolic profiling. Am J Gastroenterol. 2009 Jun;104(6):1435-44. doi: 10.1038/ajg.2009.175. Epub 2009 Apr 28.

pubmed_id:19491857

[5]:

reference_text:Marchesi JR, Holmes E, Khan F, Kochhar S, Scanlan P, Shanahan F, Wilson ID, Wang Y: Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. J Proteome Res. 2007 Feb;6(2):546-51.

pubmed_id:17269711

[6]:

reference_text:Ahmed I, Greenwood R, Costello Bde L, Ratcliffe NM, Probert CS: An investigation of fecal volatile organic metabolites in irritable bowel syndrome. PLoS One. 2013;8(3):e58204. doi: 10.1371/journal.pone.0058204. Epub 2013 Mar 13.

pubmed_id:23516449

[7]:

reference_text:Walton C, Fowler DP, Turner C, Jia W, Whitehead RN, Griffiths L, Dawson C, Waring RH, Ramsden DB, Cole JA, Cauchi M, Bessant C, Hunter JO: Analysis of volatile organic compounds of bacterial origin in chronic gastrointestinal diseases. Inflamm Bowel Dis. 2013 Sep;19(10):2069-78. doi: 10.1097/MIB.0b013e31829a91f6.

pubmed_id:23867873

[8]:

reference_text:De Preter V, Machiels K, Joossens M, Arijs I, Matthys C, Vermeire S, Rutgeerts P, Verbeke K: Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD. Gut. 2015 Mar;64(3):447-58. doi: 10.1136/gutjnl-2013-306423. Epub 2014 May 8.

pubmed_id:24811995

[9]:

reference_text:Bjerrum JT, Wang Y, Hao F, Coskun M, Ludwig C, Gunther U, Nielsen OH: Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals. Metabolomics. 2015;11:122-133. Epub 2014 Jun 1.

pubmed_id:25598765

[10]:

reference_text:Ahmed I, Greenwood R, Costello B, Ratcliffe N, Probert CS: Investigation of faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease. Aliment Pharmacol Ther. 2016 Mar;43(5):596-611. doi: 10.1111/apt.13522. Epub 2016 Jan 25.

pubmed_id:26806034

[11]:

reference_text:Lee T, Clavel T, Smirnov K, Schmidt A, Lagkouvardos I, Walker A, Lucio M, Michalke B, Schmitt-Kopplin P, Fedorak R, Haller D: Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD. Gut. 2017 May;66(5):863-871. doi: 10.1136/gutjnl-2015-309940. Epub 2016 Feb 4.

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pubmed_id:28842642

name:Ulcerative colitis

omim_id:

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pubmed_id:1740537

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pubmed_id:21761941

[6]:

pubmed_id:23516449

[7]:

pubmed_id:23867873

[8]:

pubmed_id:24811995

[9]:

pubmed_id:25598765

[10]:

pubmed_id:26806034

[11]:

pubmed_id:26848182

[12]:

pubmed_id:27609529

[13]:

pubmed_id:28842642

name:Metastatic melanoma

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name:Colorectal cancer

omim_id:114500

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name:Alzheimer's disease

omim_id:104300

[1]:

reference_text:Fonteh AN, Harrington RJ, Tsai A, Liao P, Harrington MG: Free amino acid and dipeptide changes in the body fluids from Alzheimer's disease subjects. Amino Acids. 2007 Feb;32(2):213-24. Epub 2006 Oct 10.

pubmed_id:17031479

[2]:

reference_text:Selley ML, Close DR, Stern SE: The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease. Neurobiol Aging. 2002 May-Jun;23(3):383-8.

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[3]:

reference_text:Shetty HU, Holloway HW, Schapiro MB: Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease. Clin Chem. 1996 Feb;42(2):298-302.

pubmed_id:8595727

[4]:

reference_text:Jia JP, Jia JM, Zhou WD, Xu M, Chu CB, Yan X, Sun YX: Differential acetylcholine and choline concentrations in the cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia. Chin Med J (Engl). 2004 Aug;117(8):1161-4.

pubmed_id:15361288

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reference_text:Redjems-Bennani N, Jeandel C, Lefebvre E, Blain H, Vidailhet M, Gueant JL: Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from Alzheimer patients. Gerontology. 1998;44(5):300-4.

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reference_text:Walter A, Korth U, Hilgert M, Hartmann J, Weichel O, Hilgert M, Fassbender K, Schmitt A, Klein J: Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients. Neurobiol Aging. 2004 Nov-Dec;25(10):1299-303.

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reference_text:Raskind MA, Peskind ER, Holmes C, Goldstein DS: Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and Alzheimer's disease. Biol Psychiatry. 1999 Sep 15;46(6):756-65.

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reference_text:Lovell MA, Markesbery WR: Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid. Arch Neurol. 2001 Mar;58(3):392-6.

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reference_text:Bar KJ, Franke S, Wenda B, Muller S, Kientsch-Engel R, Stein G, Sauer H: Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia. Neurobiol Aging. 2003 Mar-Apr;24(2):333-8.

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reference_text:Serot JM, Barbe F, Arning E, Bottiglieri T, Franck P, Montagne P, Nicolas JP: Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid: relation with age and Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2005 Nov;76(11):1585-7.

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reference_text:Molina JA, Jimenez-Jimenez FJ, Aguilar MV, Meseguer I, Mateos-Vega CJ, Gonzalez-Munoz MJ, de Bustos F, Porta J, Orti-Pareja M, Zurdo M, Barrios E, Martinez-Para MC: Cerebrospinal fluid levels of transition metals in patients with Alzheimer's disease. J Neural Transm (Vienna). 1998;105(4-5):479-88.

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reference_text:Hozumi I, Hasegawa T, Honda A, Ozawa K, Hayashi Y, Hashimoto K, Yamada M, Koumura A, Sakurai T, Kimura A, Tanaka Y, Satoh M, Inuzuka T: Patterns of levels of biological metals in CSF differ among neurodegenerative diseases. J Neurol Sci. 2011 Apr 15;303(1-2):95-9. doi: 10.1016/j.jns.2011.01.003. Epub 2011 Feb 2.

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reference_text:Motawaj M, Peoc'h K, Callebert J, Arrang JM: CSF levels of the histamine metabolite tele-methylhistamine are only slightly decreased in Alzheimer's disease. J Alzheimers Dis. 2010;22(3):861-71. doi: 10.3233/JAD-2010-100381.

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reference_text:Smach MA, Jacob N, Golmard JL, Charfeddine B, Lammouchi T, Ben Othman L, Dridi H, Bennamou S, Limem K: Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study. Eur Neurol. 2011;65(5):270-8. doi: 10.1159/000326301. Epub 2011 Apr 8.

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[21]:

reference_text:Linnebank M, Popp J, Smulders Y, Smith D, Semmler A, Farkas M, Kulic L, Cvetanovska G, Blom H, Stoffel-Wagner B, Kolsch H, Weller M, Jessen F: S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease. Neurodegener Dis. 2010;7(6):373-8. doi: 10.1159/000309657. Epub 2010 Jun 3.

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[22]:

reference_text:Rosler N, Wichart I, Jellinger KA: Clinical significance of neurobiochemical profiles in the lumbar cerebrospinal fluid of Alzheimer's disease patients. J Neural Transm (Vienna). 2001;108(2):231-46.

pubmed_id:11314776

[23]:

reference_text:Sunderland T, Berrettini WH, Molchan SE, Lawlor BA, Martinez RA, Vitiello B, Tariot PN, Cohen RM: Reduced cerebrospinal fluid dynorphin A1-8 in Alzheimer's disease. Biol Psychiatry. 1991 Jul 1;30(1):81-7.

pubmed_id:1716470

[24]:

reference_text:Tsuruoka M, Hara J, Hirayama A, Sugimoto M, Soga T, Shankle WR, Tomita M: Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34(19):2865-72. doi: 10.1002/elps.201300019. Epub 2013 Sep 6.

pubmed_id:23857558

name:Frontotemporal dementia

omim_id:600274

[1]:

pubmed_id:23857558

name:Lewy body disease

omim_id:

[1]:

pubmed_id:23857558

name:Attachment loss

omim_id:

[1]:

reference_text:Liebsch C, Pitchika V, Pink C, Samietz S, Kastenmuller G, Artati A, Suhre K, Adamski J, Nauck M, Volzke H, Friedrich N, Kocher T, Holtfreter B, Pietzner M: The Saliva Metabolome in Association to Oral Health Status. J Dent Res. 2019 Jun;98(6):642-651. doi: 10.1177/0022034519842853. Epub 2019 Apr 26.

pubmed_id:31026179

name:Missing teeth

omim_id:

[1]:

pubmed_id:31026179

10:

name:Periodontal Probing Depth

omim_id:

[1]:

pubmed_id:31026179

KEGG数据库编号

C00020

DrugBank数据库编号

DB00131

foodb数据库编号

FDB030677

ChemSpider数据库编号

5858

公共化学化合物编号

6083

PDB数据库编号

生物利益的化学实体数据库编号

16027

knapsack数据库编号

C00019347

维基百科编号

Adenylic_acid

代谢途径的数据库编号

AMP

苯酚资源管理器化合物数据库编号

比格数据库编号

33534

梅林编号

5111

虚拟机身份证编号

AMP

fbonto数据库编号

综合参考

一般参考

protein_accession:HMDBP00001

name:5'-nucleotidase

uniprot_id:P21589

gene_name:NT5E

protein_type:Unknown

protein_accession:HMDBP00004

name:Cytosolic 5'-nucleotidase 1B

uniprot_id:Q96P26

gene_name:NT5C1B

protein_type:Unknown

protein_accession:HMDBP00005

name:Cytosolic 5'-nucleotidase 1A

uniprot_id:Q9BXI3

gene_name:NT5C1A

protein_type:Unknown

protein_accession:HMDBP00006

name:5'(3')-deoxyribonucleotidase, cytosolic type

uniprot_id:Q8TCD5

gene_name:NT5C

protein_type:Unknown

protein_accession:HMDBP00007

name:Deoxycytidine kinase

uniprot_id:P27707

gene_name:DCK

protein_type:Enzyme

protein_accession:HMDBP00008

name:5'(3')-deoxyribonucleotidase, mitochondrial

uniprot_id:Q9NPB1

gene_name:NT5M

protein_type:Unknown

protein_accession:HMDBP00037

name:Acetyl-coenzyme A synthetase, cytoplasmic

uniprot_id:Q9NR19

gene_name:ACSS2

protein_type:Enzyme

protein_accession:HMDBP00042

name:Acetyl-coenzyme A synthetase 2-like, mitochondrial

uniprot_id:Q9NUB1

gene_name:ACSS1

protein_type:Enzyme

protein_accession:HMDBP00084

name:Ectonucleoside triphosphate diphosphohydrolase 1

uniprot_id:P49961

gene_name:ENTPD1

protein_type:Unknown

10:

protein_accession:HMDBP00085

name:Soluble calcium-activated nucleotidase 1

uniprot_id:Q8WVQ1

gene_name:CANT1

protein_type:Unknown

11:

protein_accession:HMDBP00086

name:Ectonucleoside triphosphate diphosphohydrolase 3

uniprot_id:O75355

gene_name:ENTPD3

protein_type:Unknown

12:

protein_accession:HMDBP00089

name:Serum paraoxonase/lactonase 3

uniprot_id:Q15166

gene_name:PON3

protein_type:Enzyme

13:

protein_accession:HMDBP00119

name:Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

uniprot_id:P22413

gene_name:ENPP1

protein_type:Unknown

14:

protein_accession:HMDBP00194

name:Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

uniprot_id:O14638

gene_name:ENPP3

protein_type:Unknown

15:

protein_accession:HMDBP00274

name:Phenylalanine--tRNA ligase alpha subunit

uniprot_id:Q9Y285

gene_name:FARSA

protein_type:Enzyme

16:

protein_accession:HMDBP00275

name:Phenylalanine--tRNA ligase, mitochondrial

uniprot_id:O95363

gene_name:FARS2

protein_type:Enzyme

17:

protein_accession:HMDBP00293

name:Alpha-aminoadipic semialdehyde dehydrogenase

uniprot_id:P49419

gene_name:ALDH7A1

protein_type:Unknown

18:

protein_accession:HMDBP00342

name:3'(2'),5'-bisphosphate nucleotidase 1

uniprot_id:O95861

gene_name:BPNT1

protein_type:Unknown

19:

protein_accession:HMDBP00369

name:ADP-dependent glucokinase

uniprot_id:Q9BRR6

gene_name:ADPGK

protein_type:Unknown

20:

protein_accession:HMDBP00370

name:Glycogen phosphorylase, liver form

uniprot_id:P06737

gene_name:PYGL

protein_type:Enzyme

21:

protein_accession:HMDBP00373

name:Glycogen phosphorylase, muscle form

uniprot_id:P11217

gene_name:PYGM

protein_type:Enzyme

22:

protein_accession:HMDBP00375

name:Glycogen phosphorylase, brain form

uniprot_id:P11216

gene_name:PYGB

protein_type:Enzyme

23:

protein_accession:HMDBP00438

name:Adenine phosphoribosyltransferase

uniprot_id:P07741

gene_name:APRT

protein_type:Enzyme

24:

protein_accession:HMDBP00475

name:Hypoxanthine-guanine phosphoribosyltransferase

uniprot_id:P00492

gene_name:HPRT1

protein_type:Unknown

25:

protein_accession:HMDBP00509

name:Biotin--protein ligase

uniprot_id:P50747

gene_name:HLCS

protein_type:Enzyme

26:

protein_accession:HMDBP00522

name:Phenylalanine--tRNA ligase beta subunit

uniprot_id:Q9NSD9

gene_name:FARSB

protein_type:Enzyme

27:

protein_accession:HMDBP00560

name:Ubiquitin-conjugating enzyme E2 A

uniprot_id:P49459

gene_name:UBE2A

protein_type:Enzyme

28:

protein_accession:HMDBP00561

name:Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

uniprot_id:Q13956

gene_name:PDE6H

protein_type:Enzyme

29:

protein_accession:HMDBP00562

name:Adenylate kinase isoenzyme 1

uniprot_id:P00568

gene_name:AK1

protein_type:Enzyme

30:

protein_accession:HMDBP00563

name:NEDD8-conjugating enzyme Ubc12

uniprot_id:P61081

gene_name:UBE2M

protein_type:Enzyme

31:

protein_accession:HMDBP00564

name:Ubiquitin/ISG15-conjugating enzyme E2 L6

uniprot_id:O14933

gene_name:UBE2L6

protein_type:Enzyme

32:

protein_accession:HMDBP00565

name:Glycine--tRNA ligase

uniprot_id:P41250

gene_name:GARS

protein_type:Enzyme

33:

protein_accession:HMDBP00566

name:Ribose-phosphate pyrophosphokinase 3

uniprot_id:P21108

gene_name:PRPS1L1

protein_type:Unknown

34:

protein_accession:HMDBP00567

name:Bifunctional glutamate/proline--tRNA ligase

uniprot_id:P07814

gene_name:EPRS

protein_type:Enzyme

35:

protein_accession:HMDBP00570

name:Long-chain-fatty-acid--CoA ligase 4

uniprot_id:O60488

gene_name:ACSL4

protein_type:Unknown

36:

protein_accession:HMDBP00571

name:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

uniprot_id:P54750

gene_name:PDE1A

protein_type:Unknown

37:

protein_accession:HMDBP00572

name:Ubiquitin-conjugating enzyme E2 D1

uniprot_id:P51668

gene_name:UBE2D1

protein_type:Unknown

38:

protein_accession:HMDBP00573

name:GTP:AMP phosphotransferase, mitochondrial

uniprot_id:Q9UIJ7

gene_name:AK3

protein_type:Enzyme

39:

protein_accession:HMDBP00574

name:Tryptophan--tRNA ligase, cytoplasmic

uniprot_id:P23381

gene_name:WARS

protein_type:Enzyme

40:

protein_accession:HMDBP00575

name:High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

uniprot_id:O60658

gene_name:PDE8A

protein_type:Unknown

41:

protein_accession:HMDBP00576

name:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

uniprot_id:Q01064

gene_name:PDE1B

protein_type:Enzyme

42:

protein_accession:HMDBP00577

name:Long-chain-fatty-acid--CoA ligase 1

uniprot_id:P33121

gene_name:ACSL1

protein_type:Unknown

43:

protein_accession:HMDBP00578

name:cGMP-inhibited 3',5'-cyclic phosphodiesterase B

uniprot_id:Q13370

gene_name:PDE3B

protein_type:Enzyme

44:

protein_accession:HMDBP00579

name:Ubiquitin-conjugating enzyme E2 G1

uniprot_id:P62253

gene_name:UBE2G1

protein_type:Enzyme

45:

protein_accession:HMDBP00580

name:Glutamine--tRNA ligase

uniprot_id:P47897

gene_name:QARS

protein_type:Enzyme

46:

protein_accession:HMDBP00581

name:Threonine--tRNA ligase, cytoplasmic

uniprot_id:P26639

gene_name:TARS

protein_type:Enzyme

47:

protein_accession:HMDBP00583

name:Asparagine synthetase [glutamine-hydrolyzing]

uniprot_id:P08243

gene_name:ASNS

protein_type:Enzyme

48:

protein_accession:HMDBP00584

name:Ubiquitin-conjugating enzyme E2 E2

uniprot_id:Q96LR5

gene_name:UBE2E2

protein_type:Enzyme

49:

protein_accession:HMDBP00585

name:Adenylosuccinate lyase

uniprot_id:P30566

gene_name:ADSL

protein_type:Enzyme

50:

protein_accession:HMDBP00586

name:Adenylate kinase isoenzyme 4, mitochondrial

uniprot_id:P27144

gene_name:AK4

protein_type:Enzyme

51:

protein_accession:HMDBP00587

name:Ubiquitin-conjugating enzyme E2 D2

uniprot_id:P62837

gene_name:UBE2D2

protein_type:Enzyme

52:

protein_accession:HMDBP00588

name:DNA ligase 4

uniprot_id:P49917

gene_name:LIG4

protein_type:Enzyme

53:

protein_accession:HMDBP00590

name:High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

uniprot_id:Q13946

gene_name:PDE7A

protein_type:Unknown

54:

protein_accession:HMDBP00591

name:Arginine--tRNA ligase, cytoplasmic

uniprot_id:P54136

gene_name:RARS

protein_type:Enzyme

55:

protein_accession:HMDBP00592

name:GMP synthase [glutamine-hydrolyzing]

uniprot_id:P49915

gene_name:GMPS

protein_type:Unknown

56:

protein_accession:HMDBP00593

name:Ubiquitin-conjugating enzyme E2 E3

uniprot_id:Q969T4

gene_name:UBE2E3

protein_type:Unknown

57:

protein_accession:HMDBP00595

name:Ubiquitin-conjugating enzyme E2 B

uniprot_id:P63146

gene_name:UBE2B

protein_type:Enzyme

58:

protein_accession:HMDBP00596

name:Probable leucine--tRNA ligase, mitochondrial

uniprot_id:Q15031

gene_name:LARS2

protein_type:Enzyme

59:

protein_accession:HMDBP00597

name:AMP deaminase 3

uniprot_id:Q01432

gene_name:AMPD3

protein_type:Enzyme

60:

protein_accession:HMDBP00598

name:Ubiquitin-conjugating enzyme E2 J2

uniprot_id:Q8N2K1

gene_name:UBE2J2

protein_type:Enzyme

61:

protein_accession:HMDBP00599

name:AMP deaminase 2

uniprot_id:Q01433

gene_name:AMPD2

protein_type:Enzyme

62:

protein_accession:HMDBP00600

name:cGMP-inhibited 3',5'-cyclic phosphodiesterase A

uniprot_id:Q14432

gene_name:PDE3A

protein_type:Unknown

63:

protein_accession:HMDBP00601

name:Ubiquitin-conjugating enzyme E2 L3

uniprot_id:P68036

gene_name:UBE2L3

protein_type:Enzyme

64:

protein_accession:HMDBP00602

name:RNA 3'-terminal phosphate cyclase

uniprot_id:O00442

gene_name:RTCA

protein_type:Enzyme

65:

protein_accession:HMDBP00603

name:Adenylate kinase 7

uniprot_id:Q96M32

gene_name:AK7

protein_type:Enzyme

66:

protein_accession:HMDBP00604

name:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

uniprot_id:Q9Y233

gene_name:PDE10A

protein_type:Unknown

67:

protein_accession:HMDBP00605

name:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

uniprot_id:Q14123

gene_name:PDE1C

protein_type:Unknown

68:

protein_accession:HMDBP00606

name:Tyrosine--tRNA ligase, cytoplasmic

uniprot_id:P54577

gene_name:YARS

protein_type:Enzyme

69:

protein_accession:HMDBP00607

name:DNA ligase 3

uniprot_id:P49916

gene_name:LIG3

protein_type:Unknown

70:

protein_accession:HMDBP00608

name:Aspartate--tRNA ligase, cytoplasmic

uniprot_id:P14868

gene_name:DARS

protein_type:Enzyme

71:

protein_accession:HMDBP00609

name:cAMP-specific 3',5'-cyclic phosphodiesterase 4B

uniprot_id:Q07343

gene_name:PDE4B

protein_type:Unknown

72:

protein_accession:HMDBP00610

name:Ubiquitin-conjugating enzyme E2 D3

uniprot_id:P61077

gene_name:UBE2D3

protein_type:Enzyme

73:

protein_accession:HMDBP00611

name:Asparagine--tRNA ligase, cytoplasmic

uniprot_id:O43776

gene_name:NARS

protein_type:Enzyme

74:

protein_accession:HMDBP00612

name:cAMP-specific 3',5'-cyclic phosphodiesterase 7B

uniprot_id:Q9NP56

gene_name:PDE7B

protein_type:Unknown

75:

protein_accession:HMDBP00613

name:Lysine--tRNA ligase

uniprot_id:Q15046

gene_name:KARS

protein_type:Enzyme

76:

protein_accession:HMDBP00614

name:Isoleucine--tRNA ligase, cytoplasmic

uniprot_id:P41252

gene_name:IARS

protein_type:Enzyme

77:

protein_accession:HMDBP00615

name:Bis(5'-adenosyl)-triphosphatase

uniprot_id:P49789

gene_name:FHIT

protein_type:Unknown

78:

protein_accession:HMDBP00616

name:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

uniprot_id:O76083

gene_name:PDE9A

protein_type:Unknown

79:

protein_accession:HMDBP00617

name:cGMP-dependent 3',5'-cyclic phosphodiesterase

uniprot_id:O00408

gene_name:PDE2A

protein_type:Unknown

80:

protein_accession:HMDBP00618

name:Ubiquitin-like modifier-activating enzyme 1

uniprot_id:P22314

gene_name:UBA1

protein_type:Enzyme

81:

protein_accession:HMDBP00619

name:Tyrosine--tRNA ligase, mitochondrial

uniprot_id:Q9Y2Z4

gene_name:YARS2

protein_type:Enzyme

82:

protein_accession:HMDBP00620

name:Ubiquitin-conjugating enzyme E2 E1

uniprot_id:P51965

gene_name:UBE2E1

protein_type:Enzyme

83:

protein_accession:HMDBP00621

name:Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]

uniprot_id:P50583

gene_name:NUDT2

protein_type:Unknown

84:

protein_accession:HMDBP00622

name:Long-chain-fatty-acid--CoA ligase 6

uniprot_id:Q9UKU0

gene_name:ACSL6

protein_type:Unknown

85:

protein_accession:HMDBP00623

name:Methionine--tRNA ligase, cytoplasmic

uniprot_id:P56192

gene_name:MARS

protein_type:Enzyme

86:

protein_accession:HMDBP00625

name:Alanine--tRNA ligase, cytoplasmic

uniprot_id:P49588

gene_name:AARS

protein_type:Enzyme

87:

protein_accession:HMDBP00626

name:Tryptophan--tRNA ligase, mitochondrial

uniprot_id:Q9UGM6

gene_name:WARS2

protein_type:Enzyme

88:

protein_accession:HMDBP00627

name:ADP-sugar pyrophosphatase

uniprot_id:Q9UKK9

gene_name:NUDT5

protein_type:Unknown

89:

protein_accession:HMDBP00628

name:Ribose-phosphate pyrophosphokinase 1

uniprot_id:P60891

gene_name:PRPS1

protein_type:Unknown

90:

protein_accession:HMDBP00629

name:Serine--tRNA ligase, mitochondrial

uniprot_id:Q9NP81

gene_name:SARS2

protein_type:Enzyme

91:

protein_accession:HMDBP00630

name:High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

uniprot_id:O95263

gene_name:PDE8B

protein_type:Unknown

92:

protein_accession:HMDBP00631

name:cAMP-specific 3',5'-cyclic phosphodiesterase 4C

uniprot_id:Q08493

gene_name:PDE4C

protein_type:Unknown

93:

protein_accession:HMDBP00632

name:Ribose-phosphate pyrophosphokinase 2

uniprot_id:P11908

gene_name:PRPS2

protein_type:Unknown

94:

protein_accession:HMDBP00633

name:Thiamin pyrophosphokinase 1

uniprot_id:Q9H3S4

gene_name:TPK1

protein_type:Enzyme

95:

protein_accession:HMDBP00635

name:SUMO-conjugating enzyme UBC9

uniprot_id:P63279

gene_name:UBE2I

protein_type:Enzyme

96:

protein_accession:HMDBP00636

name:cAMP-specific 3',5'-cyclic phosphodiesterase 4D

uniprot_id:Q08499

gene_name:PDE4D

protein_type:Unknown

97:

protein_accession:HMDBP00637

name:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

uniprot_id:P18545

gene_name:PDE6G

protein_type:Enzyme

98:

protein_accession:HMDBP00639

name:ADP-ribose pyrophosphatase, mitochondrial

uniprot_id:Q9BW91

gene_name:NUDT9

protein_type:Unknown

99:

protein_accession:HMDBP00640

name:Adenosine kinase

uniprot_id:P55263

gene_name:ADK

protein_type:Unknown

100:

protein_accession:HMDBP00641

name:Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

uniprot_id:O43924

gene_name:PDE6D

protein_type:Enzyme

101:

protein_accession:HMDBP00642

name:Probable histidine--tRNA ligase, mitochondrial

uniprot_id:P49590

gene_name:HARS2

protein_type:Enzyme

102:

protein_accession:HMDBP00643

name:Ubiquitin-conjugating enzyme E2 J1

uniprot_id:Q9Y385

gene_name:UBE2J1

protein_type:Enzyme

103:

protein_accession:HMDBP00644

name:Long-chain-fatty-acid--CoA ligase 5

uniprot_id:Q9ULC5

gene_name:ACSL5

protein_type:Unknown

104:

protein_accession:HMDBP00645

name:Histidine--tRNA ligase, cytoplasmic

uniprot_id:P12081

gene_name:HARS

protein_type:Enzyme

105:

protein_accession:HMDBP00646

name:Serine--tRNA ligase, cytoplasmic

uniprot_id:P49591

gene_name:SARS

protein_type:Enzyme

106:

protein_accession:HMDBP00647

name:Long-chain-fatty-acid--CoA ligase 3

uniprot_id:O95573

gene_name:ACSL3

protein_type:Unknown

107:

protein_accession:HMDBP00648

name:Leucine--tRNA ligase, cytoplasmic

uniprot_id:Q9P2J5

gene_name:LARS

protein_type:Enzyme

108:

protein_accession:HMDBP00649

name:Ubiquitin-conjugating enzyme E2 C

uniprot_id:O00762

gene_name:UBE2C

protein_type:Enzyme

109:

protein_accession:HMDBP00650

name:cAMP-specific 3',5'-cyclic phosphodiesterase 4A

uniprot_id:P27815

gene_name:PDE4A

protein_type:Unknown

110:

protein_accession:HMDBP00651

name:Valine--tRNA ligase

uniprot_id:P26640

gene_name:VARS

protein_type:Enzyme

111:

protein_accession:HMDBP00652

name:Adenylate kinase isoenzyme 5

uniprot_id:Q9Y6K8

gene_name:AK5

protein_type:Unknown

112:

protein_accession:HMDBP00653

name:Selenide, water dikinase 1

uniprot_id:P49903

gene_name:SEPHS1

protein_type:Enzyme

113:

protein_accession:HMDBP00654

name:Ubiquitin-conjugating enzyme E2 N

uniprot_id:P61088

gene_name:UBE2N

protein_type:Enzyme

114:

protein_accession:HMDBP00655

name:cGMP-specific 3',5'-cyclic phosphodiesterase

uniprot_id:O76074

gene_name:PDE5A

protein_type:Unknown

115:

protein_accession:HMDBP00656

name:Argininosuccinate synthase

uniprot_id:P00966

gene_name:ASS1

protein_type:Enzyme

116:

protein_accession:HMDBP00657

name:AMP deaminase 1

uniprot_id:P23109

gene_name:AMPD1

protein_type:Enzyme

117:

protein_accession:HMDBP00658

name:Selenide, water dikinase 2

uniprot_id:Q99611

gene_name:SEPHS2

protein_type:Enzyme

118:

protein_accession:HMDBP00660

name:DNA ligase 1

uniprot_id:P18858

gene_name:LIG1

protein_type:Enzyme

119:

protein_accession:HMDBP00711

name:Adenylate cyclase type 1

uniprot_id:Q08828

gene_name:ADCY1

protein_type:Unknown

120:

protein_accession:HMDBP01653

name:Histidine triad nucleotide-binding protein 1

uniprot_id:P49773

gene_name:HINT1

protein_type:Unknown

121:

protein_accession:HMDBP01946

name:Very long-chain acyl-CoA synthetase

uniprot_id:O14975

gene_name:SLC27A2

protein_type:Enzyme

122:

protein_accession:HMDBP01995

name:Transient receptor potential cation channel subfamily M member 2

uniprot_id:O94759

gene_name:TRPM2

protein_type:Unknown

123:

protein_accession:HMDBP02017

name:Adenylyltransferase and sulfurtransferase MOCS3

uniprot_id:O95396

gene_name:MOCS3

protein_type:Enzyme

124:

protein_accession:HMDBP02133

name:Cyclic AMP-responsive element-binding protein 1

uniprot_id:P16220

gene_name:CREB1

protein_type:Unknown

125:

protein_accession:HMDBP02282

name:E3 ubiquitin-protein ligase NEDD4-like

uniprot_id:Q96PU5

gene_name:NEDD4L

protein_type:Enzyme

126:

protein_accession:HMDBP02432

name:E3 ubiquitin-protein ligase Mdm2

uniprot_id:Q00987

gene_name:MDM2

protein_type:Unknown

127:

protein_accession:HMDBP02553

name:Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)

uniprot_id:Q3LXA3

gene_name:DAK

protein_type:Enzyme

128:

protein_accession:HMDBP02892

name:Gephyrin

uniprot_id:Q9NQX3

gene_name:GPHN

protein_type:Unknown

129:

protein_accession:HMDBP03007

name:Phosphopantothenate--cysteine ligase

uniprot_id:Q9HAB8

gene_name:PPCS

protein_type:Enzyme

130:

protein_accession:HMDBP03055

name:Bile acyl-CoA synthetase

uniprot_id:Q9Y2P5

gene_name:SLC27A5

protein_type:Enzyme

131:

protein_accession:HMDBP03189

name:Cytosolic 5'-nucleotidase 3

uniprot_id:Q9H0P0

gene_name:NT5C3

protein_type:Enzyme

132:

protein_accession:HMDBP03241

name:Glutamine-dependent NAD(+) synthetase

uniprot_id:Q6IA69

gene_name:NADSYN1

protein_type:Unknown

133:

protein_accession:HMDBP03750

name:Cytosolic purine 5'-nucleotidase

uniprot_id:P49902

gene_name:NT5C2

protein_type:Unknown

134:

protein_accession:HMDBP04072

name:Adenylate kinase 2, mitochondrial

uniprot_id:P54819

gene_name:AK2

protein_type:Enzyme

135:

protein_accession:HMDBP04109

name:Acetoacetyl-CoA synthetase

uniprot_id:Q86V21

gene_name:AACS

protein_type:Enzyme

136:

protein_accession:HMDBP04188

name:Acyl-coenzyme A synthetase ACSM1, mitochondrial

uniprot_id:Q08AH1

gene_name:ACSM1

protein_type:Unknown

137:

protein_accession:HMDBP04379

name:Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

uniprot_id:Q9HCR9

gene_name:PDE11A

protein_type:Unknown

138:

protein_accession:HMDBP07360

name:Probable arginine--tRNA ligase, mitochondrial

uniprot_id:Q5T160

gene_name:RARS2

protein_type:Enzyme

139:

protein_accession:HMDBP07369

name:Probable cysteine--tRNA ligase, mitochondrial

uniprot_id:Q9HA77

gene_name:CARS2

protein_type:Unknown

140:

protein_accession:HMDBP07382

name:Probable glutamate--tRNA ligase, mitochondrial

uniprot_id:Q5JPH6

gene_name:EARS2

protein_type:Enzyme

141:

protein_accession:HMDBP07399

name:Acyl-CoA synthetase family member 4

uniprot_id:Q4L235

gene_name:AASDH

protein_type:Enzyme

142:

protein_accession:HMDBP07403

name:Peroxisomal NADH pyrophosphatase NUDT12

uniprot_id:Q9BQG2

gene_name:NUDT12

protein_type:Unknown

143:

protein_accession:HMDBP07406

name:ACSS2 protein

uniprot_id:Q96FY7

gene_name:ACSS2

protein_type:Enzyme

144:

protein_accession:HMDBP07421

name:Valine--tRNA ligase, mitochondrial

uniprot_id:Q5ST30

gene_name:VARS2

protein_type:Enzyme

145:

protein_accession:HMDBP07558

name:E3 ubiquitin-protein ligase CBL

uniprot_id:P22681

gene_name:CBL

protein_type:Unknown

146:

protein_accession:HMDBP07560

name:Signal transduction protein CBL-C

uniprot_id:Q9ULV8

gene_name:CBLC

protein_type:Unknown

147:

protein_accession:HMDBP07670

name:Ectonucleoside triphosphate diphosphohydrolase 8

uniprot_id:Q5MY95

gene_name:ENTPD8

protein_type:Unknown

148:

protein_accession:HMDBP08299

name:Acyl-coenzyme A synthetase ACSM6, mitochondrial

uniprot_id:Q6P461

gene_name:ACSM6

protein_type:Unknown

149:

protein_accession:HMDBP08447

name:Probable E3 ubiquitin-protein ligase HERC1

uniprot_id:Q15751

gene_name:HERC1

protein_type:Unknown

150:

protein_accession:HMDBP08656

name:E3 ubiquitin-protein ligase HERC2

uniprot_id:O95714

gene_name:HERC2

protein_type:Unknown

151:

protein_accession:HMDBP08663

name:Nuclear respiratory factor 1

uniprot_id:Q16656

gene_name:NRF1

protein_type:Unknown

152:

protein_accession:HMDBP08699

name:Acyl-coenzyme A synthetase ACSM2A, mitochondrial

uniprot_id:Q08AH3

gene_name:ACSM2A

protein_type:Unknown

153:

protein_accession:HMDBP08700

name:Acyl-coenzyme A synthetase ACSM2B, mitochondrial

uniprot_id:Q68CK6

gene_name:ACSM2B

protein_type:Unknown

154:

protein_accession:HMDBP08701

name:Acyl-coenzyme A synthetase ACSM3, mitochondrial

uniprot_id:Q53FZ2

gene_name:ACSM3

protein_type:Unknown

155:

protein_accession:HMDBP08702

name:Acyl-coenzyme A synthetase ACSM5, mitochondrial

uniprot_id:Q6NUN0

gene_name:ACSM5

protein_type:Unknown

156:

protein_accession:HMDBP08732

name:Inositol monophosphatase 3

uniprot_id:Q9NX62

gene_name:IMPAD1

protein_type:Unknown

157:

protein_accession:HMDBP08775

name:Diphosphoinositol polyphosphate phosphohydrolase 3-alpha

uniprot_id:Q8NFP7

gene_name:NUDT10

protein_type:Unknown

158:

protein_accession:HMDBP08776

name:Diphosphoinositol polyphosphate phosphohydrolase 3-beta

uniprot_id:Q96G61

gene_name:NUDT11

protein_type:Unknown

159:

protein_accession:HMDBP08844

name:Carnosine synthase 1

uniprot_id:A5YM72

gene_name:CARNS1

protein_type:Unknown

160:

protein_accession:HMDBP09123

name:Acyl-coenzyme A synthetase ACSM4, mitochondrial

uniprot_id:P0C7M7

gene_name:ACSM4

protein_type:Unknown

161:

protein_accession:HMDBP09248

name:Probable threonine--tRNA ligase 2, cytoplasmic

uniprot_id:A2RTX5

gene_name:TARSL2

protein_type:Enzyme

162:

protein_accession:HMDBP09249

name:Threonine--tRNA ligase, mitochondrial

uniprot_id:Q9BW92

gene_name:TARS2

protein_type:Enzyme

163:

protein_accession:HMDBP09251

name:Methionine--tRNA ligase, mitochondrial

uniprot_id:Q96GW9

gene_name:MARS2

protein_type:Enzyme

164:

protein_accession:HMDBP09252

name:Aspartate--tRNA ligase, mitochondrial

uniprot_id:Q6PI48

gene_name:DARS2

protein_type:Enzyme

165:

protein_accession:HMDBP09253

name:Cysteine--tRNA ligase, cytoplasmic

uniprot_id:P49589

gene_name:CARS

protein_type:Enzyme

166:

protein_accession:HMDBP09254

name:FARSLA protein

uniprot_id:Q6IBR2

gene_name:FARSLA

protein_type:Enzyme

167:

protein_accession:HMDBP09255

name:Probable asparagine--tRNA ligase, mitochondrial

uniprot_id:Q96I59

gene_name:NARS2

protein_type:Enzyme

168:

protein_accession:HMDBP09256

name:SUMO-activating enzyme subunit 2

uniprot_id:Q9UBT2

gene_name:UBA2

protein_type:Enzyme

169:

protein_accession:HMDBP09257

name:E3 ubiquitin-protein ligase HUWE1

uniprot_id:Q7Z6Z7

gene_name:HUWE1

protein_type:Enzyme

170:

protein_accession:HMDBP09258

name:E3 ubiquitin-protein ligase Topors

uniprot_id:Q9NS56

gene_name:TOPORS

protein_type:Enzyme

171:

protein_accession:HMDBP09259

name:STIP1 homology and U-box containing protein 1 (STIP1 homology and U- box containing protein 1, isoform CRA_c)

uniprot_id:Q9UNE7

gene_name:STUB1

protein_type:Enzyme

172:

protein_accession:HMDBP09260

name:Ubiquitin conjugation factor E4 B

uniprot_id:O95155

gene_name:UBE4B

protein_type:Enzyme

173:

protein_accession:HMDBP09261

name:Membrane-associated ring finger (C3HC4) 6 (Membrane-associated ring finger (C3HC4) 6, isoform CRA_a)

uniprot_id:O60337

gene_name:MARCH6

protein_type:Enzyme

174:

protein_accession:HMDBP09262

name:TGIF-interacting ubiquitin ligase 1

uniprot_id:Q9H0M0

gene_name:

protein_type:Enzyme

175:

protein_accession:HMDBP09263

name:NEDD4-like E3 ubiquitin-protein ligase WWP2

uniprot_id:O00308

gene_name:WWP2

protein_type:Enzyme

176:

protein_accession:HMDBP09264

name:E3 ubiquitin-protein ligase MARCH3

uniprot_id:Q86UD3

gene_name:MARCH3

protein_type:Enzyme

177:

protein_accession:HMDBP09265

name:NEDD8-conjugating enzyme UBE2F

uniprot_id:Q969M7

gene_name:UBE2F

protein_type:Enzyme

178:

protein_accession:HMDBP09266

name:Ubiquitin-conjugating enzyme E2 U

uniprot_id:Q5VVX9

gene_name:UBE2U

protein_type:Enzyme

179:

protein_accession:HMDBP09267

name:Probable E3 ubiquitin-protein ligase MARCH10

uniprot_id:Q8NA82

gene_name:MARCH10

protein_type:Enzyme

180:

protein_accession:HMDBP09268

name:E3 ubiquitin-protein ligase UBR1

uniprot_id:Q8IWV7

gene_name:UBR1

protein_type:Enzyme

181:

protein_accession:HMDBP09269

name:E3 ubiquitin-protein ligase MARCH8

uniprot_id:Q5T0T0

gene_name:MARCH8

protein_type:Enzyme

182:

protein_accession:HMDBP09270

name:E3 ubiquitin-protein ligase ZNRF2

uniprot_id:Q8NHG8

gene_name:ZNRF2

protein_type:Enzyme

183:

protein_accession:HMDBP09271

name:E3 ubiquitin-protein ligase TRIM32

uniprot_id:Q13049

gene_name:TRIM32

protein_type:Enzyme

184:

protein_accession:HMDBP09272

name:Probable E3 ubiquitin-protein ligase MYCBP2

uniprot_id:O75592

gene_name:MYCBP2

protein_type:Enzyme

185:

protein_accession:HMDBP09273

name:E3 ubiquitin-protein ligase MGRN1

uniprot_id:O60291

gene_name:MGRN1

protein_type:Enzyme

186:

protein_accession:HMDBP09274

name:E3 ubiquitin-protein ligase UBR2

uniprot_id:Q8IWV8

gene_name:UBR2

protein_type:Enzyme

187:

protein_accession:HMDBP09275

name:E3 ubiquitin-protein ligase UBR4

uniprot_id:Q5T4S7

gene_name:UBR4

protein_type:Enzyme

188:

protein_accession:HMDBP09276

name:E3 ubiquitin-protein ligase AMFR

uniprot_id:Q9UKV5

gene_name:AMFR

protein_type:Enzyme

189:

protein_accession:HMDBP09277

name:Ubiquitin-conjugating enzyme E2 S

uniprot_id:Q16763

gene_name:UBE2S

protein_type:Enzyme

190:

protein_accession:HMDBP09278

name:Pre-mRNA-processing factor 19

uniprot_id:Q9UMS4

gene_name:PRPF19

protein_type:Enzyme

191:

protein_accession:HMDBP09279

name:Myosin regulatory light chain interacting protein (Myosin regulatory light chain interacting protein, isoform CRA_a)

uniprot_id:Q8WY64

gene_name:MYLIP

protein_type:Enzyme

192:

protein_accession:HMDBP09280

name:HNP95

uniprot_id:Q96T88

gene_name:hNp95

protein_type:Enzyme

193:

protein_accession:HMDBP09281

name:Putative ubiquitin-conjugating enzyme E2 N-like

uniprot_id:Q5JXB2

gene_name:UBE2NL

protein_type:Enzyme

194:

protein_accession:HMDBP09282

name:Midline-1

uniprot_id:O15344

gene_name:MID1

protein_type:Enzyme

195:

protein_accession:HMDBP09283

name:E3 ubiquitin-protein ligase NEDD4

uniprot_id:P46934

gene_name:NEDD4

protein_type:Enzyme

196:

protein_accession:HMDBP09284

name:CCR4-NOT transcription complex subunit 4

uniprot_id:O95628

gene_name:CNOT4

protein_type:Enzyme

197:

protein_accession:HMDBP09285

name:E3 ubiquitin-protein ligase MARCH2

uniprot_id:Q9P0N8

gene_name:MARCH2

protein_type:Enzyme

198:

protein_accession:HMDBP09286

name:E3 ubiquitin-protein ligase UBR5

uniprot_id:O95071

gene_name:UBR5

protein_type:Enzyme

199:

protein_accession:HMDBP09287

name:E3 ubiquitin-protein ligase TRIM33

uniprot_id:Q9UPN9

gene_name:TRIM33

protein_type:Enzyme

200:

protein_accession:HMDBP09288

name:E3 ubiquitin-protein ligase MARCH5

uniprot_id:Q9NX47

gene_name:MARCH5

protein_type:Enzyme

201:

protein_accession:HMDBP09289

name:Ubiquitin-conjugating enzyme E2 R2

uniprot_id:Q712K3

gene_name:UBE2R2

protein_type:Enzyme

202:

protein_accession:HMDBP09290

name:E3 ubiquitin-protein ligase MARCH1

uniprot_id:Q8TCQ1

gene_name:MARCH1

protein_type:Enzyme

203:

protein_accession:HMDBP09291

name:E3 ubiquitin-protein ligase FANCL

uniprot_id:Q9NW38

gene_name:FANCL

protein_type:Enzyme

204:

protein_accession:HMDBP09292

name:Ubiquitin-like modifier-activating enzyme 6

uniprot_id:A0AVT1

gene_name:UBA6

protein_type:Enzyme

205:

protein_accession:HMDBP09293

name:Ubiquitin-conjugating enzyme E2 W

uniprot_id:Q96B02

gene_name:UBE2W

protein_type:Enzyme

206:

protein_accession:HMDBP09294

name:Galactosyl transferase-associated protein

uniprot_id:Q29SN7

gene_name:GTAP

protein_type:Enzyme

207:

protein_accession:HMDBP09295

name:E3 ubiquitin-protein ligase CHFR

uniprot_id:Q96EP1

gene_name:CHFR

protein_type:Enzyme

208:

protein_accession:HMDBP09296

name:Ring finger protein 20

uniprot_id:Q5VTR2

gene_name:RNF20

protein_type:Enzyme

209:

protein_accession:HMDBP09297

name:E3 ubiquitin-protein ligase RAD18

uniprot_id:Q9NS91

gene_name:RAD18

protein_type:Enzyme

210:

protein_accession:HMDBP09298

name:E3 ubiquitin ligase SMURF1

uniprot_id:Q9HCE7

gene_name:SMURF1

protein_type:Enzyme

211:

protein_accession:HMDBP09299

name:Baculoviral IAP repeat-containing protein 6

uniprot_id:Q9NR09

gene_name:BIRC6

protein_type:Enzyme

212:

protein_accession:HMDBP09300

name:E3 ubiquitin-protein ligase MARCH4

uniprot_id:Q9P2E8

gene_name:MARCH4

protein_type:Enzyme

213:

protein_accession:HMDBP09301

name:E3 ubiquitin-protein ligase CCNB1IP1

uniprot_id:Q9NPC3

gene_name:CCNB1IP1

protein_type:Enzyme

214:

protein_accession:HMDBP09302

name:E3 ubiquitin-protein ligase RNF5

uniprot_id:Q99942

gene_name:RNF5

protein_type:Enzyme

215:

protein_accession:HMDBP09303

name:Ubiquitin-conjugating enzyme E2 O

uniprot_id:Q9C0C9

gene_name:UBE2O

protein_type:Enzyme

216:

protein_accession:HMDBP09304

name:Praja 1

uniprot_id:A2A322

gene_name:PJA1

protein_type:Enzyme

217:

protein_accession:HMDBP09305

name:RFWD2 protein

uniprot_id:Q05CT6

gene_name:RFWD2

protein_type:Enzyme

218:

protein_accession:HMDBP09306

name:E3 ubiquitin-protein ligase SMURF2

uniprot_id:Q9HAU4

gene_name:SMURF2

protein_type:Enzyme

219:

protein_accession:HMDBP09307

name:E3 ubiquitin-protein ligase SIAH1

uniprot_id:Q8IUQ4

gene_name:SIAH1

protein_type:Enzyme

220:

protein_accession:HMDBP09308

name:E3 ubiquitin-protein ligase SIAH2

uniprot_id:O43255

gene_name:SIAH2

protein_type:Enzyme

221:

protein_accession:HMDBP09309

name:E3 ubiquitin-protein ligase MARCH7

uniprot_id:Q9H992

gene_name:MARCH7

protein_type:Enzyme

222:

protein_accession:HMDBP09310

name:Ubiquitin-conjugating enzyme E2 Z

uniprot_id:Q9H832

gene_name:UBE2Z

protein_type:Enzyme

223:

protein_accession:HMDBP09311

name:Ubiquitin-like modifier-activating enzyme 7

uniprot_id:P41226

gene_name:UBA7

protein_type:Enzyme

224:

protein_accession:HMDBP09312

name:Ubiquitin carrier protein

uniprot_id:A4D1L5

gene_name:UBE2H

protein_type:Enzyme

225:

protein_accession:HMDBP09313

name:Ubiquitin-protein ligase E3A

uniprot_id:Q05086

gene_name:UBE3A

protein_type:Enzyme

226:

protein_accession:HMDBP09314

name:E3 ubiquitin-protein ligase RNF128

uniprot_id:Q8TEB7

gene_name:RNF128

protein_type:Enzyme

227:

protein_accession:HMDBP09315

name:E3 ubiquitin-protein ligase TRIM11

uniprot_id:Q96F44

gene_name:TRIM11

protein_type:Enzyme

228:

protein_accession:HMDBP09316

name:BRCA1 associated protein variant

uniprot_id:Q59H81

gene_name:

protein_type:Enzyme

229:

protein_accession:HMDBP09317

name:E3 ubiquitin-protein ligase synoviolin

uniprot_id:Q86TM6

gene_name:SYVN1

protein_type:Enzyme

230:

protein_accession:HMDBP09318

name:E3 ubiquitin-protein ligase TRIM63

uniprot_id:Q969Q1

gene_name:TRIM63

protein_type:Enzyme

231:

protein_accession:HMDBP09319

name:E3 ubiquitin-protein ligase LNX

uniprot_id:Q8TBB1

gene_name:LNX1

protein_type:Enzyme

232:

protein_accession:HMDBP09320

name:E3 ubiquitin-protein ligase ZNRF1

uniprot_id:Q8ND25

gene_name:ZNRF1

protein_type:Enzyme

233:

protein_accession:HMDBP09321

name:Tripartite motif-containing protein 5

uniprot_id:Q9C035

gene_name:TRIM5

protein_type:Enzyme

234:

protein_accession:HMDBP09323

name:Ubiquitin-protein ligase E3B

uniprot_id:Q7Z3V4

gene_name:UBE3B

protein_type:Enzyme

235:

protein_accession:HMDBP09324

name:E3 ubiquitin-protein ligase RNF8

uniprot_id:O76064

gene_name:RNF8

protein_type:Enzyme

236:

protein_accession:HMDBP09325

name:E3 ubiquitin-protein ligase LRSAM1

uniprot_id:Q6UWE0

gene_name:LRSAM1

protein_type:Enzyme

237:

protein_accession:HMDBP09326

name:Ubiquitin-conjugating enzyme E2 Q2

uniprot_id:Q8WVN8

gene_name:UBE2Q2

protein_type:Enzyme

238:

protein_accession:HMDBP09327

name:E3 ubiquitin-protein ligase MARCH9

uniprot_id:Q86YJ5

gene_name:MARCH9

protein_type:Enzyme

239:

protein_accession:HMDBP09328

name:Probable E3 ubiquitin-protein ligase TRIP12

uniprot_id:Q14669

gene_name:TRIP12

protein_type:Enzyme

240:

protein_accession:HMDBP09329

name:E3 ubiquitin-protein ligase DZIP3

uniprot_id:Q86Y13

gene_name:DZIP3

protein_type:Enzyme

241:

protein_accession:HMDBP09330

name:Ubiquitin-protein ligase E3C

uniprot_id:Q15386

gene_name:UBE3C

protein_type:Enzyme

242:

protein_accession:HMDBP10671

name:Alanine--tRNA ligase, mitochondrial

uniprot_id:Q5JTZ9

gene_name:AARS2

protein_type:Enzyme

243:

protein_accession:HMDBP10675

name:Isoleucine--tRNA ligase, mitochondrial

uniprot_id:Q9NSE4

gene_name:IARS2

protein_type:Enzyme

244:

protein_accession:HMDBP10680

name:Lipoyltransferase 1, mitochondrial

uniprot_id:Q9Y234

gene_name:LIPT1

protein_type:Enzyme

245:

protein_accession:HMDBP10694

name:Probable proline--tRNA ligase, mitochondrial

uniprot_id:Q7L3T8

gene_name:PARS2

protein_type:Enzyme

246:

protein_accession:HMDBP11004

name:Long-chain-fatty-acid--CoA ligase ACSBG2

uniprot_id:Q5FVE4

gene_name:ACSBG2

protein_type:Enzyme

247:

protein_accession:HMDBP11005

name:Long-chain-fatty-acid--CoA ligase ACSBG1

uniprot_id:Q96GR2

gene_name:ACSBG1

protein_type:Enzyme

248:

protein_accession:HMDBP11557

name:E3 ubiquitin-protein ligase MIB1

uniprot_id:Q86YT6

gene_name:MIB1

protein_type:Enzyme

249:

protein_accession:HMDBP11561

name:E3 ubiquitin-protein ligase RNF138

uniprot_id:Q8WVD3

gene_name:RNF138

protein_type:Enzyme

250:

protein_accession:HMDBP11563

name:E3 ubiquitin-protein ligase RING2

uniprot_id:Q99496

gene_name:RNF2

protein_type:Enzyme

251:

protein_accession:HMDBP11565

name:L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

uniprot_id:Q9NRN7

gene_name:AASDHPPT

protein_type:Enzyme

252:

protein_accession:HMDBP11566

name:SUMO-activating enzyme subunit 1

uniprot_id:Q9UBE0

gene_name:SAE1

protein_type:Enzyme

253:

protein_accession:HMDBP11571

name:Ubiquitin-conjugating enzyme E2 D4

uniprot_id:Q9Y2X8

gene_name:UBE2D4

protein_type:Enzyme

254:

protein_accession:HMDBP11575

name:Ubiquitin conjugation factor E4 A

uniprot_id:Q14139

gene_name:UBE4A

protein_type:Enzyme

255:

protein_accession:HMDBP11581

name:E3 ubiquitin-protein ligase RNF144B

uniprot_id:Q7Z419

gene_name:RNF144B

protein_type:Enzyme

256:

protein_accession:HMDBP11602

name:Acyl-CoA synthetase short-chain family member 3, mitochondrial

uniprot_id:Q9H6R3

gene_name:ACSS3

protein_type:Unknown

257:

protein_accession:HMDBP11603

name:Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase

uniprot_id:Q3LIE5

gene_name:ADPRM

protein_type:Unknown

258:

protein_accession:HMDBP11798

name:Adenylate kinase isoenzyme 6

uniprot_id:Q9Y3D8

gene_name:TAF9

protein_type:Unknown

259:

protein_accession:HMDBP11799

name:Adenylate kinase 8

uniprot_id:Q96MA6

gene_name:AK8

protein_type:Unknown

260:

protein_accession:HMDBP11927

name:tRNA-splicing ligase RtcB homolog

uniprot_id:Q9Y3I0

gene_name:C22orf28

protein_type:Unknown

261:

protein_accession:HMDBP11977

name:Probable tRNA(His) guanylyltransferase

uniprot_id:Q9NWX6

gene_name:THG1L

protein_type:Unknown

262:

protein_accession:HMDBP11982

name:E3 ubiquitin/ISG15 ligase TRIM25

uniprot_id:Q14258

gene_name:TRIM25

protein_type:Unknown

263:

protein_accession:HMDBP11986

name:Ubiquitin-conjugating enzyme E2Q-like protein 1

uniprot_id:A1L167

gene_name:UBE2QL1

protein_type:Unknown

264:

protein_accession:HMDBP11989

name:Ubiquitin-conjugating enzyme E2 G2

uniprot_id:P60604

gene_name:UBE2G2

protein_type:Unknown

265:

protein_accession:HMDBP11990

name:Ubiquitin-conjugating enzyme E2 Q1

uniprot_id:Q7Z7E8

gene_name:UBE2Q1

protein_type:Unknown

266:

protein_accession:HMDBP11991

name:Ubiquitin-conjugating enzyme E2 R1

uniprot_id:P49427

gene_name:CDC34

protein_type:Unknown

267:

protein_accession:HMDBP11992

name:Ubiquitin-conjugating enzyme E2 H

uniprot_id:P62256

gene_name:UBE2H

protein_type:Unknown

268:

protein_accession:HMDBP11993

name:Ubiquitin-conjugating enzyme E2 K

uniprot_id:P61086

gene_name:UBE2K

protein_type:Unknown

269:

protein_accession:HMDBP11994

name:Ubiquitin-conjugating enzyme E2 T

uniprot_id:Q9NPD8

gene_name:UBE2T

protein_type:Unknown

蛋白质结合

reference_text:Eells JT, Spector R: Purine and pyrimidine base and nucleoside concentrations in human cerebrospinal fluid and plasma. Neurochem Res. 1983 Nov;8(11):1451-7.

pubmed_id:6656991

reference_text:Nakayama Y, Kinoshita A, Tomita M: Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. Theor Biol Med Model. 2005 May 9;2:18.

pubmed_id:15882454

reference_text:BISHOP C, RANKINE DM, TALBOTT JH: The nucleotides in normal human blood. J Biol Chem. 1959 May;234(5):1233-7.

pubmed_id:13654353

reference_text:Lin CY, Ishida M: Elevation of cAMP levels in cerebrospinal fluid of patients with neonatal meningitis. Pediatrics. 1983 Jun;71(6):932-4.

pubmed_id:6304612

reference_text:Pagani R, Tabucchi A, Carlucci F, Leoncini R, Consolmagno E, Molinelli M, Valerio P: Some aspects of purine nucleotide metabolism in human lymphocytes before and after infection with HIV-1 virus: nucleotide content. Adv Exp Med Biol. 1991;309B:43-6.

pubmed_id:1781403

reference_text:Drezner MK, Neelon FA, Curtis HB, Lebovitz HE: Renal cyclic adenosine monophosphate: an accurate index of parathyroid function. Metabolism. 1976 Oct;25(10):1103-12.

pubmed_id:184364

reference_text:Aschenbach WG, Sakamoto K, Goodyear LJ: 5' adenosine monophosphate-activated protein kinase, metabolism and exercise. Sports Med. 2004;34(2):91-103.

pubmed_id:14965188

reference_text:Subramanian GM, Cronin PW, Poley G, Weinstein A, Stoughton SM, Zhong J, Ou Y, Zmuda JF, Osborn BL, Freimuth WW: A phase 1 study of PAmAb, a fully human monoclonal antibody against Bacillus anthracis protective antigen, in healthy volunteers. Clin Infect Dis. 2005 Jul 1;41(1):12-20. Epub 2005 May 24.

pubmed_id:15937757

reference_text:Aurbach GD: Genetic disorders involving parathyroid hormone and calcitonin. Birth Defects Orig Artic Ser. 1971 May;7(6):48-54.

pubmed_id:4155962

10:

reference_text:Post RM, Cramer H, Goodwin FK: Cyclic AMP in cerebrospinal fluid of manic and depressive patients. Psychol Med. 1977 Nov;7(4):599-605.

pubmed_id:201957

11:

reference_text:Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043.

pubmed_id:32033212

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综合参考
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蛋白质结合

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