版本
5.0
创建日期
2005-11-16 15:48:42 UTC
更新日期
2021-09-14 15:39:00 UTC
登录号
HMDB0000295
地位
quantified
二级访问
HMDB00295

名称
Uridine 5'-diphosphate
描述
Uridine 5'-diphosphate, also known as 5'-UDP, UDP or uridine diphosphoric acid, belongs to the class of organic compounds known as pyrimidine ribonucleoside diphosphates. These are pyrimidine ribonucleotides with diphosphate group linked to the ribose moiety. UDP is also classified as a nucleotide diphosphate. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of a pyrophosphate group, a pentose sugar ribose, and the nucleobase uracil. UDP exists in all living species, ranging from bacteria to plants to humans. In mammals UDP is an important factor in glycogenesis or the formation of glycogen in the liver. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. UDP is also an important extracellular pyrimidine signaling molecule that mediates diverse biological effects via P1 and P2 purinergic receptors, such as the uptake of thymidine and proliferation of gliomas. UDP plays a key role in the function of Uridine 5'-diphospho-glucuronosyltransferases (UDP-glucuronosyltransferases, UGTs) which catalyze the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. UDP-Glucuronosyltransferases are responsible for the process of glucuronidation, a major part of phase II metabolism. The reaction catalyzed by UGT enzymes involves the addition of a glucuronic acid moiety to xenobiotics and is the most important pathway for the human body's elimination of the most frequently prescribed drugs. It is also the major pathway for foreign chemical (dietary, environmental, pharmaceutical) removal for most drugs, dietary substances, toxins and endogenous substances. UGT is present in humans, other animals, plants, and bacteria. Famously, UGT enzymes are not present in the genus Felis (PMID: 10862526) and this accounts for a number of unusual toxicities in the cat family.
同义词
1:Uridine diphosphate

2:Uridine diphosphoric acid

3:Uridine 5'-diphosphoric acid

4:5'-UDP

5:UDP

6:Uridine 5'-pyrophosphate

7:Uridine 5'-pyrophosphorate

8:Uridine 5'-pyrophosphoric acid

9:Uridine pyrophosphate

10:Pyrophosphate, uridine

11:Diphosphate, uridine

12:5’-UDP

13:Uridine 5'-(trihydrogen pyrophosphate)

14:Uridine 5'-diphosphate

15:Uridine 5’-(trihydrogen pyrophosphate)

16:Uridine 5’-diphosphate

17:Uridine 5’-diphosphoric acid

18:Uridine 5’-pyrophosphate

19:Uridine 5’-pyrophosphoric acid

化学式
C9H14N2O12P2
平均分子量
404.1612
等位分子量
404.002196946
化学名称
[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
传统名称
UDP
CAS 登记号
58-98-0
代谢物结构字符串
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
inchi标识符
InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
印记键
XCCTYIAWTASOJW-XVFCMESISA-N
分类学
description: belongs to the class of organic compounds known as pyrimidine ribonucleoside diphosphates. These are pyrimidine ribonucleotides with diphosphate group linked to the ribose moiety.

description:Pyrimidine ribonucleoside diphosphates

kingdom:Organic compounds

super_class:Nucleosides, nucleotides, and analogues

class:Pyrimidine nucleotides

sub_class:Pyrimidine ribonucleotides

molecular_framework:Aromatic heteromonocyclic compounds

1:1,2-diols

2:Azacyclic compounds

3:Glycosylamines

4:Heteroaromatic compounds

5:Hydrocarbon derivatives

6:Hydropyrimidines

7:Hydroxypyrimidines

8:Monoalkyl phosphates

9:Monosaccharide phosphates

10:Organic oxides

11:Organic pyrophosphates

12:Organonitrogen compounds

13:Organopnictogen compounds

14:Oxacyclic compounds

15:Pentose phosphates

16:Pyrimidones

17:Secondary alcohols

18:Tetrahydrofurans

19:1,2-diol

20:Alcohol

21:Alkyl phosphate

22:Aromatic heteromonocyclic compound

23:Azacycle

24:Glycosyl compound

25:Heteroaromatic compound

26:Hydrocarbon derivative

27:Hydropyrimidine

28:Hydroxypyrimidine

29:Monoalkyl phosphate

30:Monosaccharide

31:Monosaccharide phosphate

32:N-glycosyl compound

33:Organic nitrogen compound

34:Organic oxide

35:Organic oxygen compound

36:Organic phosphoric acid derivative

37:Organic pyrophosphate

38:Organoheterocyclic compound

39:Organonitrogen compound

40:Organooxygen compound

41:Organopnictogen compound

42:Oxacycle

43:Pentose phosphate

44:Pentose-5-phosphate

45:Phosphoric acid ester

46:Pyrimidine

47:Pyrimidine ribonucleoside diphosphate

48:Pyrimidone

49:Secondary alcohol

50:Tetrahydrofuran

51:Ribonucleotides

52:pyrimidine ribonucleoside 5'-diphosphate

53:uridine 5'-phosphate

本体论
term:Disposition

definition:A concept that describes the origin of a chemical, its location within an organism, or its route of exposure.

parent_id:

level:1

type:parent

term:Route of exposure

definition:A mean by which a chemical agent comes in contact with an organism, either under intended or unintended circumstances.

parent_id:7724

*level:2

type:parent

term:Enteral

definition:Chemical exposure via the alimentary canal (mouth to anus).

parent_id:7743

**level:3

type:parent

term:Ingestion

definition:Chemical exposure facilitated by entry through the mouth.

parent_id:7744

***level:4

type:child

synonym:Digestion

term:Source

definition:Natural or synthetic origin of a chemical.

parent_id:7724

*level:2

type:parent

term:Endogenous

definition:

parent_id:7735

**level:3

type:child

term:Food

definition:

parent_id:7735

**level:3

type:child

term:Biological

definition:A living organism (species or a higher taxonomy rank), in which a chemical can be found.

parent_id:7735

**level:3

type:parent

term:Plant

definition:A living organism belonging to the kingdom plantea. typically, it grows in a permanent site, absorbs water and inorganic substances through its roots, and synthesizes nutrients in its leaves by photosynthesis using the green pigment chlorophyll. examples incude trees, shrubs, herbs, grasses, ferns, and mosses.

parent_id:7736

***level:4

type:parent

synonym:Flora

term:Animal

definition:A living organism belonging to the kingdom animalia. it feeds on organic matter, typically having specialized sense organs and nervous system and able to respond rapidly to stimuli.

parent_id:7736

***level:4

type:child

synonym:Fauna

term:Biological location

definition:The physiological origin within an organism, including anatomical compnents, biofluids and excreta.

parent_id:7724

*level:2

type:parent

term:Organ and components

definition:An anatomical organizational level including multiple tissues or substructures, which enables a common biological function.

parent_id:7725

**level:3

type:parent

term:Prostate

definition:The male reproductive accessory gland that produces prostatic fluid and is located adjacent to or around the urethra distal to the urinary bladder in mammals. (nci).

parent_id:7727

***level:4

type:child

synonym:Prostate gland

term:Endocrine gland

definition:

parent_id:7727

***level:4

type:parent

term:Tissue and substructures

definition:An anatomical organizational level including multiple cells yet not comprising a complete organ .

parent_id:7725

**level:3

type:parent

term:Placenta

definition:An organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin b. (nci).

parent_id:7729

***level:4

type:child

term:Biofluid and excreta

definition:A liquid, semi-solid or solid material originating in the body.

parent_id:7725

**level:3

type:parent

term:Blood

definition:A liquid tissue with the primary function of transporting oxygen and carbon dioxide (nci). it supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection.

parent_id:7731

***level:4

type:child

term:Subcellular

definition:An anatomical organizational level including a component within a biological cell .

parent_id:7725

**level:3

type:parent

term:Cytoplasm

definition:The portion of the cell contained within the plasma membrane but excluding the nucleus.

parent_id:7730

***level:4

type:child

synonym:Cytoplasma

term:Mitochondria

definition:

parent_id:7730

***level:4

type:child

term:Nucleus

definition:A body within the cell, surrounded by a membrane, within which lie the chromosomes, one or more nucleoli, combined with proteins, and exhibits mitosis. (NCI)

parent_id:7730

***level:4

type:child

synonym:Cell nucleus

synonym:Nucleic

term:Lysosome

definition:В A sac-like compartment inside a cell that has enzymes that can break down cellular components that need to be destroyed. (NCI).

parent_id:7730

***level:4

type:child

term:Endoplasmic reticulum

definition:A network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials. (Infoplease Dictionary via NCI)

parent_id:7730

***level:4

type:child

synonym:Er

term:Golgi

definition:A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. Note that the Golgi apparatus can be located in various places in the cytoplasm.

parent_id:7730

***level:4

type:child

synonym:Golgi apparatus

synonym:Golgi complex

synonym:Golgi ribbon

term:Cell and elements

definition:An anatomical organizational level comprising of a single cell (or a fragment in some exceptions). a cell is defined by its type or function. it is the smallest unit of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid.

parent_id:7725

**level:3

type:parent

term:Extracellular

definition:The space external to the outermost structure of a cell.

parent_id:7732

***level:4

type:child

synonym:Extracellular region

term:Process

definition:Biological or chemical events, or a series thereof, leading to a known function or end-product.

parent_id:

level:1

type:parent

term:Naturally occurring process

definition:Naturally-occurring molecular events or a series thereof, leading to a known function or end-product.

parent_id:7659

*level:2

type:parent

term:Biological process

definition:Biological or chemical events or a series thereof, leading to a known function or end-product within an organism.

parent_id:7660

**level:3

type:parent

term:Biochemical pathway

definition:A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.

parent_id:7661

***level:4

type:parent

term:Role

definition:The purpose or function assumed by a chemical, either naturally or as intended by humans .

parent_id:

level:1

type:parent

term:Industrial application

definition:The assumed function of a chemical utilized by human.

parent_id:7671

*level:2

type:parent

term:Pharmaceutical industry

definition:A pharmacologic activity for which a chemical substance is utilized owing to its biological role.

parent_id:7678

**level:3

type:parent

term:Pharmaceutical

definition:

parent_id:7679

***level:4

type:child

状态
Solid
实验性质
预测性质
1:

kind:logp

value:-0.94

source:ALOGPS

2:

kind:logs

value:-1.66

source:ALOGPS

3:

kind:solubility

value:8.89 g/L

source:ALOGPS

4:

kind:logp

value:-3

source:ChemAxon

5:

kind:pka_strongest_acidic

value:1.77

source:ChemAxon

6:

kind:pka_strongest_basic

value:-3.7

source:ChemAxon

7:

kind:iupac

value:[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid

source:ChemAxon

8:

kind:average_mass

value:404.1612

source:ChemAxon

9:

kind:mono_mass

value:404.002196946

source:ChemAxon

10:

kind:smiles

value:O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O

source:ChemAxon

11:

kind:formula

value:C9H14N2O12P2

source:ChemAxon

12:

kind:inchi

value:InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

source:ChemAxon

13:

kind:inchikey

value:XCCTYIAWTASOJW-XVFCMESISA-N

source:ChemAxon

14:

kind:polar_surface_area

value:212.39

source:ChemAxon

15:

kind:refractivity

value:74.31

source:ChemAxon

16:

kind:polarizability

value:30.43

source:ChemAxon

17:

kind:rotatable_bond_count

value:6

source:ChemAxon

18:

kind:acceptor_count

value:10

source:ChemAxon

19:

kind:donor_count

value:6

source:ChemAxon

20:

kind:physiological_charge

value:-2

source:ChemAxon

21:

kind:formal_charge

value:0

source:ChemAxon

22:

kind:number_of_rings

value:2

source:ChemAxon

23:

kind:bioavailability

value:No

source:ChemAxon

24:

kind:rule_of_five

value:No

source:ChemAxon

25:

kind:ghose_filter

value:No

source:ChemAxon

26:

kind:veber_rule

value:No

source:ChemAxon

27:

kind:mddr_like_rule

value:No

source:ChemAxon

1:

type:Specdb::NmrTwoD

spectrum_id:1260

2:

type:Specdb::CMs

spectrum_id:22299

3:

type:Specdb::CMs

spectrum_id:37408

4:

type:Specdb::CMs

spectrum_id:149344

5:

type:Specdb::MsMs

spectrum_id:501

6:

type:Specdb::MsMs

spectrum_id:502

7:

type:Specdb::MsMs

spectrum_id:503

8:

type:Specdb::MsMs

spectrum_id:3932

9:

type:Specdb::MsMs

spectrum_id:179256

10:

type:Specdb::MsMs

spectrum_id:179257

11:

type:Specdb::MsMs

spectrum_id:179258

12:

type:Specdb::MsMs

spectrum_id:181581

13:

type:Specdb::MsMs

spectrum_id:181582

14:

type:Specdb::MsMs

spectrum_id:181583

15:

type:Specdb::MsMs

spectrum_id:439115

16:

type:Specdb::MsMs

spectrum_id:2253196

17:

type:Specdb::MsMs

spectrum_id:2253283

18:

type:Specdb::MsMs

spectrum_id:2255259

19:

type:Specdb::MsMs

spectrum_id:2255294

20:

type:Specdb::MsMs

spectrum_id:2257370

21:

type:Specdb::MsMs

spectrum_id:2259177

22:

type:Specdb::MsMs

spectrum_id:2259374

23:

type:Specdb::MsMs

spectrum_id:2286802

24:

type:Specdb::MsMs

spectrum_id:2286803

25:

type:Specdb::MsMs

spectrum_id:2286804

26:

type:Specdb::MsMs

spectrum_id:3082461

27:

type:Specdb::MsMs

spectrum_id:3082462

28:

type:Specdb::MsMs

spectrum_id:3082463

29:

type:Specdb::NmrOneD

spectrum_id:1318

30:

type:Specdb::NmrOneD

spectrum_id:4834

31:

type:Specdb::NmrOneD

spectrum_id:4835

32:

type:Specdb::NmrOneD

spectrum_id:143390

33:

type:Specdb::NmrOneD

spectrum_id:143391

34:

type:Specdb::NmrOneD

spectrum_id:143392

35:

type:Specdb::NmrOneD

spectrum_id:143393

36:

type:Specdb::NmrOneD

spectrum_id:143394

37:

type:Specdb::NmrOneD

spectrum_id:143395

38:

type:Specdb::NmrOneD

spectrum_id:143396

39:

type:Specdb::NmrOneD

spectrum_id:143397

40:

type:Specdb::NmrOneD

spectrum_id:143398

41:

type:Specdb::NmrOneD

spectrum_id:143399

42:

type:Specdb::NmrOneD

spectrum_id:143400

43:

type:Specdb::NmrOneD

spectrum_id:143401

44:

type:Specdb::NmrOneD

spectrum_id:143402

45:

type:Specdb::NmrOneD

spectrum_id:143403

46:

type:Specdb::NmrOneD

spectrum_id:143404

47:

type:Specdb::NmrOneD

spectrum_id:143405

48:

type:Specdb::NmrOneD

spectrum_id:143406

49:

type:Specdb::NmrOneD

spectrum_id:143407

50:

type:Specdb::NmrOneD

spectrum_id:143408

51:

type:Specdb::NmrOneD

spectrum_id:143409

光谱
生物学性质
1:

cellular:(1):Cytoplasm

cellular:(2):Endoplasmic reticulum

cellular:(3):Extracellular

cellular:(4):Golgi apparatus

cellular:(5):Lysosome

cellular:(6):Mitochondria

cellular:(7):Nucleus

2:

biospecimen:(1):Blood

3:

tissue:(1):Placenta

tissue:(2):Prostate

tissue:(3):Thyroid Gland

4:

[1]:

name:17-Beta Hydroxysteroid Dehydrogenase III Deficiency

smpdb_id:SMP00356

kegg_map_id:

[2]:

name:Acetaminophen Metabolism Pathway

smpdb_id:SMP00640

kegg_map_id:

[3]:

name:Acute Intermittent Porphyria

smpdb_id:SMP00344

kegg_map_id:

[4]:

name:Amino Sugar Metabolism

smpdb_id:SMP00045

kegg_map_id:map00520

[5]:

name:Androgen and Estrogen Metabolism

smpdb_id:SMP00068

kegg_map_id:map00150

[6]:

name:Androstenedione Metabolism

smpdb_id:SMP30406

kegg_map_id:

[7]:

name:Aromatase deficiency

smpdb_id:SMP00565

kegg_map_id:

[8]:

name:Artemether Metabolism Pathway

smpdb_id:SMP00651

kegg_map_id:

[9]:

name:Beta Ureidopropionase Deficiency

smpdb_id:SMP00172

kegg_map_id:

[10]:

name:Celecoxib Action Pathway

smpdb_id:SMP00096

kegg_map_id:

[11]:

name:Celecoxib Metabolism Pathway

smpdb_id:SMP00644

kegg_map_id:

[12]:

name:Codeine Action Pathway

smpdb_id:SMP00405

kegg_map_id:

[13]:

name:Codeine Metabolism Pathway

smpdb_id:SMP00621

kegg_map_id:

[14]:

name:Congenital disorder of glycosylation CDG-IId

smpdb_id:SMP00579

kegg_map_id:

[15]:

name:Congenital Erythropoietic Porphyria (CEP) or Gunther Disease

smpdb_id:SMP00345

kegg_map_id:

[16]:

name:Dihydropyrimidinase Deficiency

smpdb_id:SMP00178

kegg_map_id:

[17]:

name:Estrone Metabolism

smpdb_id:SMP30880

kegg_map_id:

[18]:

name:Etoposide Action Pathway

smpdb_id:SMP00442

kegg_map_id:

[19]:

name:Etoposide Metabolism Pathway

smpdb_id:SMP00601

kegg_map_id:

[20]:

name:Fabry disease

smpdb_id:SMP00525

kegg_map_id:

[21]:

name:G(M2)-Gangliosidosis: Variant B, Tay-sachs disease

smpdb_id:SMP00534

kegg_map_id:

[22]:

name:Galactose Metabolism

smpdb_id:SMP00043

kegg_map_id:map00052

[23]:

name:Galactosemia

smpdb_id:SMP00182

kegg_map_id:

[24]:

name:Gaucher Disease

smpdb_id:SMP00349

kegg_map_id:

[25]:

name:Globoid Cell Leukodystrophy

smpdb_id:SMP00348

kegg_map_id:

[26]:

name:GLUT-1 deficiency syndrome

smpdb_id:SMP00580

kegg_map_id:

[27]:

name:Glycogen synthetase deficiency

smpdb_id:SMP00552

kegg_map_id:

[28]:

name:Glycogenosis, Type III. Cori disease, Debrancher glycogenosis

smpdb_id:SMP00553

kegg_map_id:

[29]:

name:Glycogenosis, Type IV. Amylopectinosis, Anderson disease

smpdb_id:SMP00554

kegg_map_id:

[30]:

name:Glycogenosis, Type VI. Hers disease

smpdb_id:SMP00555

kegg_map_id:

[31]:

name:Hereditary Coproporphyria (HCP)

smpdb_id:SMP00342

kegg_map_id:

[32]:

name:Ibuprofen Action Pathway

smpdb_id:SMP00086

kegg_map_id:

[33]:

name:Ibuprofen Metabolism Pathway

smpdb_id:SMP00590

kegg_map_id:

[34]:

name:Irinotecan Action Pathway

smpdb_id:SMP00433

kegg_map_id:

[35]:

name:Irinotecan Metabolism Pathway

smpdb_id:SMP00600

kegg_map_id:

[36]:

name:Krabbe disease

smpdb_id:SMP00526

kegg_map_id:

[37]:

name:Lactose Synthesis

smpdb_id:SMP00444

kegg_map_id:

[38]:

name:Lamivudine Metabolism Pathway

smpdb_id:SMP00649

kegg_map_id:

[39]:

name:Metachromatic Leukodystrophy (MLD)

smpdb_id:SMP00347

kegg_map_id:

[40]:

name:MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)

smpdb_id:SMP00202

kegg_map_id:

[41]:

name:Morphine Action Pathway

smpdb_id:SMP00406

kegg_map_id:

[42]:

name:Morphine Metabolism Pathway

smpdb_id:SMP00622

kegg_map_id:

[43]:

name:Mucopolysaccharidosis VI. Sly syndrome

smpdb_id:SMP00556

kegg_map_id:

[44]:

name:Mycophenolic Acid Metabolism Pathway

smpdb_id:SMP00652

kegg_map_id:

[45]:

name:Nevirapine Metabolism Pathway

smpdb_id:SMP00642

kegg_map_id:

[46]:

name:Nicotine Action Pathway

smpdb_id:SMP00431

kegg_map_id:

[47]:

name:Nicotine Metabolism Pathway

smpdb_id:SMP00628

kegg_map_id:

[48]:

name:Phenytoin (Antiarrhythmic) Action Pathway

smpdb_id:SMP00327

kegg_map_id:

[49]:

name:Porphyria Variegata (PV)

smpdb_id:SMP00346

kegg_map_id:

[50]:

name:Porphyrin Metabolism

smpdb_id:SMP00024

kegg_map_id:map00860

[51]:

name:Pyrimidine metabolism

smpdb_id:

kegg_map_id:map00240

[52]:

name:Salla Disease/Infantile Sialic Acid Storage Disease

smpdb_id:SMP00240

kegg_map_id:

[53]:

name:Sialuria or French Type Sialuria

smpdb_id:SMP00216

kegg_map_id:

[54]:

name:Sorafenib Metabolism Pathway

smpdb_id:SMP00648

kegg_map_id:

[55]:

name:Starch and sucrose metabolism

smpdb_id:

kegg_map_id:map00500

[56]:

name:Starch and Sucrose Metabolism

smpdb_id:SMP00058

kegg_map_id:map00500

[57]:

name:Sucrase-isomaltase deficiency

smpdb_id:SMP00557

kegg_map_id:

[58]:

name:Tamoxifen Action Pathway

smpdb_id:SMP00471

kegg_map_id:

[59]:

name:Tamoxifen Metabolism Pathway

smpdb_id:SMP00606

kegg_map_id:

[60]:

name:Tay-Sachs Disease

smpdb_id:SMP00390

kegg_map_id:

[61]:

name:Tramadol Metabolism Pathway

smpdb_id:SMP00637

kegg_map_id:

[62]:

name:UMP Synthase Deficiency (Orotic Aciduria)

smpdb_id:SMP00219

kegg_map_id:

[63]:

name:Valproic Acid Metabolism Pathway

smpdb_id:SMP00635

kegg_map_id:

正常浓度
1:

biospecimen:Blood

concentration_value:41.0 +/- 12.0

concentration_units:uM

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

异常浓度
疾病参考
KEGG数据库编号
C00015
DrugBank数据库编号
DB03435
foodb数据库编号
FDB031236
ChemSpider数据库编号
5809
公共化学化合物编号
6031
PDB数据库编号
生物利益的化学实体数据库编号
17659
knapsack数据库编号
C00007313
维基百科编号
Uridine_Diphosphate
代谢途径的数据库编号
UDP
苯酚资源管理器化合物数据库编号
比格数据库编号
33518
梅林编号
虚拟机身份证编号
UDP
fbonto数据库编号
综合参考
Zeng, Bin; Rao, Linfan; Li, Gaowo. Method for manufacturing uridine diphosphate. Faming Zhuanli Shenqing Gongkai Shuomingshu (2007), 14pp.
一般参考
1:

protein_accession:HMDBP00003

name:UMP-CMP kinase

uniprot_id:P30085

gene_name:CMPK1

protein_type:Unknown

2:

protein_accession:HMDBP00084

name:Ectonucleoside triphosphate diphosphohydrolase 1

uniprot_id:P49961

gene_name:ENTPD1

protein_type:Unknown

3:

protein_accession:HMDBP00085

name:Soluble calcium-activated nucleotidase 1

uniprot_id:Q8WVQ1

gene_name:CANT1

protein_type:Unknown

4:

protein_accession:HMDBP00086

name:Ectonucleoside triphosphate diphosphohydrolase 3

uniprot_id:O75355

gene_name:ENTPD3

protein_type:Unknown

5:

protein_accession:HMDBP00105

name:Uridine-cytidine kinase 1

uniprot_id:Q9HA47

gene_name:UCK1

protein_type:Unknown

6:

protein_accession:HMDBP00106

name:Nucleoside diphosphate kinase, mitochondrial

uniprot_id:O00746

gene_name:NME4

protein_type:Unknown

7:

protein_accession:HMDBP00108

name:Ribonucleoside-diphosphate reductase large subunit

uniprot_id:P23921

gene_name:RRM1

protein_type:Enzyme

8:

protein_accession:HMDBP00109

name:Nucleoside diphosphate kinase A

uniprot_id:P15531

gene_name:NME1

protein_type:Unknown

9:

protein_accession:HMDBP00110

name:Nucleoside diphosphate kinase 7

uniprot_id:Q9Y5B8

gene_name:NME7

protein_type:Unknown

10:

protein_accession:HMDBP00111

name:Ribonucleoside-diphosphate reductase subunit M2

uniprot_id:P31350

gene_name:RRM2

protein_type:Unknown

11:

protein_accession:HMDBP00112

name:Nucleoside diphosphate kinase B

uniprot_id:P22392

gene_name:NME2

protein_type:Unknown

12:

protein_accession:HMDBP00113

name:Nucleoside diphosphate kinase 3

uniprot_id:Q13232

gene_name:NME3

protein_type:Unknown

13:

protein_accession:HMDBP00114

name:Nucleoside diphosphate kinase 6

uniprot_id:O75414

gene_name:NME6

protein_type:Unknown

14:

protein_accession:HMDBP00332

name:Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

uniprot_id:Q9Y223

gene_name:GNE

protein_type:Enzyme

15:

protein_accession:HMDBP00371

name:Beta-1,4-galactosyltransferase 2

uniprot_id:O60909

gene_name:B4GALT2

protein_type:Unknown

16:

protein_accession:HMDBP00372

name:Alpha-lactalbumin

uniprot_id:P00709

gene_name:LALBA

protein_type:Enzyme

17:

protein_accession:HMDBP00377

name:Beta-1,4-galactosyltransferase 1

uniprot_id:P15291

gene_name:B4GALT1

protein_type:Unknown

18:

protein_accession:HMDBP00449

name:UDP-glucuronosyltransferase 2B28

uniprot_id:Q9BY64

gene_name:UGT2B28

protein_type:Enzyme

19:

protein_accession:HMDBP00458

name:UDP-glucuronosyltransferase 2B4

uniprot_id:P06133

gene_name:UGT2B4

protein_type:Enzyme

20:

protein_accession:HMDBP00462

name:Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

uniprot_id:O60568

gene_name:PLOD3

protein_type:Unknown

21:

protein_accession:HMDBP00465

name:Chondroitin sulfate N-acetylgalactosaminyltransferase 1

uniprot_id:Q8TDX6

gene_name:CSGALNACT1

protein_type:Enzyme

22:

protein_accession:HMDBP00478

name:UDP-glucuronosyltransferase 1-4

uniprot_id:P22310

gene_name:UGT1A4

protein_type:Enzyme

23:

protein_accession:HMDBP00479

name:UDP-glucuronosyltransferase 2B10

uniprot_id:P36537

gene_name:UGT2B10

protein_type:Enzyme

24:

protein_accession:HMDBP00480

name:UDP-glucuronosyltransferase 2B7

uniprot_id:P16662

gene_name:UGT2B7

protein_type:Enzyme

25:

protein_accession:HMDBP00481

name:UDP-glucuronosyltransferase 2B15

uniprot_id:P54855

gene_name:UGT2B15

protein_type:Enzyme

26:

protein_accession:HMDBP00482

name:UDP-glucuronosyltransferase 2A1

uniprot_id:Q9Y4X1

gene_name:UGT2A1

protein_type:Enzyme

27:

protein_accession:HMDBP00483

name:UDP-glucuronosyltransferase 1-1

uniprot_id:P22309

gene_name:UGT1A1

protein_type:Enzyme

28:

protein_accession:HMDBP00484

name:UDP-glucuronosyltransferase 1-9

uniprot_id:O60656

gene_name:UGT1A9

protein_type:Enzyme

29:

protein_accession:HMDBP00485

name:UDP-glucuronosyltransferase 1-8

uniprot_id:Q9HAW9

gene_name:UGT1A8

protein_type:Enzyme

30:

protein_accession:HMDBP00486

name:UDP-glucuronosyltransferase 1-3

uniprot_id:P35503

gene_name:UGT1A3

protein_type:Enzyme

31:

protein_accession:HMDBP00487

name:UDP-glucuronosyltransferase 1-10

uniprot_id:Q9HAW8

gene_name:UGT1A10

protein_type:Enzyme

32:

protein_accession:HMDBP00488

name:UDP-glucuronosyltransferase 2B17

uniprot_id:O75795

gene_name:UGT2B17

protein_type:Enzyme

33:

protein_accession:HMDBP00489

name:UDP-glucuronosyltransferase 1-6

uniprot_id:P19224

gene_name:UGT1A6

protein_type:Enzyme

34:

protein_accession:HMDBP00490

name:UDP-glucuronosyltransferase 1-5

uniprot_id:P35504

gene_name:UGT1A5

protein_type:Enzyme

35:

protein_accession:HMDBP00491

name:UDP-glucuronosyltransferase 2B11

uniprot_id:O75310

gene_name:UGT2B11

protein_type:Enzyme

36:

protein_accession:HMDBP00494

name:UDP-glucuronosyltransferase 1-7

uniprot_id:Q9HAW7

gene_name:UGT1A7

protein_type:Enzyme

37:

protein_accession:HMDBP00573

name:GTP:AMP phosphotransferase, mitochondrial

uniprot_id:Q9UIJ7

gene_name:AK3

protein_type:Enzyme

38:

protein_accession:HMDBP00734

name:6-phosphofructokinase type C

uniprot_id:Q01813

gene_name:PFKP

protein_type:Unknown

39:

protein_accession:HMDBP00758

name:6-phosphofructokinase, liver type

uniprot_id:P17858

gene_name:PFKL

protein_type:Unknown

40:

protein_accession:HMDBP00762

name:6-phosphofructokinase, muscle type

uniprot_id:P08237

gene_name:PFKM

protein_type:Unknown

41:

protein_accession:HMDBP00763

name:Pyruvate kinase isozymes M1/M2

uniprot_id:P14618

gene_name:PKM

protein_type:Unknown

42:

protein_accession:HMDBP00765

name:Pyruvate kinase isozymes R/L

uniprot_id:P30613

gene_name:PKLR

protein_type:Unknown

43:

protein_accession:HMDBP00845

name:Ceramide glucosyltransferase

uniprot_id:Q16739

gene_name:UGCG

protein_type:Enzyme

44:

protein_accession:HMDBP00873

name:Beta-1,4 N-acetylgalactosaminyltransferase 1

uniprot_id:Q00973

gene_name:B4GALNT1

protein_type:Enzyme

45:

protein_accession:HMDBP00874

name:Lactosylceramide 4-alpha-galactosyltransferase

uniprot_id:Q9NPC4

gene_name:A4GALT

protein_type:Enzyme

46:

protein_accession:HMDBP00877

name:Ectonucleoside triphosphate diphosphohydrolase 4

uniprot_id:Q9Y227

gene_name:ENTPD4

protein_type:Unknown

47:

protein_accession:HMDBP00878

name:Ectonucleoside triphosphate diphosphohydrolase 6

uniprot_id:O75354

gene_name:ENTPD6

protein_type:Unknown

48:

protein_accession:HMDBP00879

name:Ectonucleoside triphosphate diphosphohydrolase 5

uniprot_id:O75356

gene_name:ENTPD5

protein_type:Unknown

49:

protein_accession:HMDBP00933

name:Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

uniprot_id:O94766

gene_name:B3GAT3

protein_type:Unknown

50:

protein_accession:HMDBP00934

name:Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

uniprot_id:Q9NPZ5

gene_name:B3GAT2

protein_type:Unknown

51:

protein_accession:HMDBP00935

name:Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

uniprot_id:Q9P2W7

gene_name:B3GAT1

protein_type:Unknown

52:

protein_accession:HMDBP00940

name:Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

uniprot_id:Q9BRB3

gene_name:PIGQ

protein_type:Enzyme

53:

protein_accession:HMDBP00941

name:Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

uniprot_id:P37287

gene_name:PIGA

protein_type:Enzyme

54:

protein_accession:HMDBP00942

name:Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

uniprot_id:Q14442

gene_name:PIGH

protein_type:Enzyme

55:

protein_accession:HMDBP00943

name:Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

uniprot_id:P57054

gene_name:PIGP

protein_type:Enzyme

56:

protein_accession:HMDBP00944

name:Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

uniprot_id:Q92535

gene_name:PIGC

protein_type:Enzyme

57:

protein_accession:HMDBP00981

name:Dolichyl-phosphate beta-glucosyltransferase

uniprot_id:Q9Y673

gene_name:ALG5

protein_type:Enzyme

58:

protein_accession:HMDBP00993

name:Polypeptide N-acetylgalactosaminyltransferase 11

uniprot_id:Q8NCW6

gene_name:GALNT11

protein_type:Unknown

59:

protein_accession:HMDBP00994

name:Polypeptide N-acetylgalactosaminyltransferase 4

uniprot_id:Q8N4A0

gene_name:GALNT4

protein_type:Unknown

60:

protein_accession:HMDBP00995

name:Polypeptide N-acetylgalactosaminyltransferase 3

uniprot_id:Q14435

gene_name:GALNT3

protein_type:Unknown

61:

protein_accession:HMDBP00996

name:Probable polypeptide N-acetylgalactosaminyltransferase 8

uniprot_id:Q9NY28

gene_name:GALNT8

protein_type:Unknown

62:

protein_accession:HMDBP00997

name:Polypeptide N-acetylgalactosaminyltransferase-like protein 2

uniprot_id:Q8N3T1

gene_name:GALNTL2

protein_type:Unknown

63:

protein_accession:HMDBP00998

name:Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1

uniprot_id:Q8N428

gene_name:GALNTL1

protein_type:Unknown

64:

protein_accession:HMDBP00999

name:Polypeptide N-acetylgalactosaminyltransferase 10

uniprot_id:Q86SR1

gene_name:GALNT10

protein_type:Unknown

65:

protein_accession:HMDBP01000

name:Polypeptide N-acetylgalactosaminyltransferase 13

uniprot_id:Q8IUC8

gene_name:GALNT13

protein_type:Unknown

66:

protein_accession:HMDBP01001

name:Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3

uniprot_id:Q6IS24

gene_name:WBSCR17

protein_type:Unknown

67:

protein_accession:HMDBP01002

name:Putative polypeptide N-acetylgalactosaminyltransferase-like protein 4

uniprot_id:Q6P9A2

gene_name:GALNTL4

protein_type:Unknown

68:

protein_accession:HMDBP01003

name:N-acetylgalactosaminyltransferase 7

uniprot_id:Q86SF2

gene_name:GALNT7

protein_type:Unknown

69:

protein_accession:HMDBP01004

name:Polypeptide N-acetylgalactosaminyltransferase 6

uniprot_id:Q8NCL4

gene_name:GALNT6

protein_type:Unknown

70:

protein_accession:HMDBP01005

name:Polypeptide N-acetylgalactosaminyltransferase 14

uniprot_id:Q96FL9

gene_name:GALNT14

protein_type:Unknown

71:

protein_accession:HMDBP01006

name:Polypeptide N-acetylgalactosaminyltransferase 2

uniprot_id:Q10471

gene_name:GALNT2

protein_type:Unknown

72:

protein_accession:HMDBP01007

name:Polypeptide N-acetylgalactosaminyltransferase 12

uniprot_id:Q8IXK2

gene_name:GALNT12

protein_type:Unknown

73:

protein_accession:HMDBP01008

name:Polypeptide N-acetylgalactosaminyltransferase 1

uniprot_id:Q10472

gene_name:GALNT1

protein_type:Unknown

74:

protein_accession:HMDBP01009

name:Polypeptide N-acetylgalactosaminyltransferase 5

uniprot_id:Q7Z7M9

gene_name:GALNT5

protein_type:Unknown

75:

protein_accession:HMDBP01032

name:Beta-1,4-galactosyltransferase 3

uniprot_id:O60512

gene_name:B4GALT3

protein_type:Unknown

76:

protein_accession:HMDBP01033

name:Beta-1,4-galactosyltransferase 4

uniprot_id:O60513

gene_name:B4GALT4

protein_type:Unknown

77:

protein_accession:HMDBP01054

name:UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

uniprot_id:O75752

gene_name:B3GALNT1

protein_type:Unknown

78:

protein_accession:HMDBP01091

name:Glycogen [starch] synthase, liver

uniprot_id:P54840

gene_name:GYS2

protein_type:Enzyme

79:

protein_accession:HMDBP01093

name:Glycogenin-1

uniprot_id:P46976

gene_name:GYG1

protein_type:Unknown

80:

protein_accession:HMDBP01094

name:Glycogen [starch] synthase, muscle

uniprot_id:P13807

gene_name:GYS1

protein_type:Enzyme

81:

protein_accession:HMDBP01095

name:Glycogenin-2

uniprot_id:O15488

gene_name:GYG2

protein_type:Unknown

82:

protein_accession:HMDBP01100

name:Histo-blood group ABO system transferase

uniprot_id:P16442

gene_name:ABO

protein_type:Unknown

83:

protein_accession:HMDBP01101

name:2-hydroxyacylsphingosine 1-beta-galactosyltransferase

uniprot_id:Q16880

gene_name:UGT8

protein_type:Enzyme

84:

protein_accession:HMDBP01102

name:Beta-1,3-galactosyltransferase 4

uniprot_id:O96024

gene_name:B3GALT4

protein_type:Enzyme

85:

protein_accession:HMDBP01103

name:Chondroitin sulfate synthase 3

uniprot_id:Q70JA7

gene_name:CHSY3

protein_type:Unknown

86:

protein_accession:HMDBP01104

name:Chondroitin sulfate synthase 2

uniprot_id:Q8IZ52

gene_name:CHPF

protein_type:Unknown

87:

protein_accession:HMDBP01105

name:Chondroitin sulfate synthase 1

uniprot_id:Q86X52

gene_name:CHSY1

protein_type:Unknown

88:

protein_accession:HMDBP01290

name:Polyribonucleotide nucleotidyltransferase 1, mitochondrial

uniprot_id:Q8TCS8

gene_name:PNPT1

protein_type:Enzyme

89:

protein_accession:HMDBP01609

name:Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

uniprot_id:Q10469

gene_name:MGAT2

protein_type:Enzyme

90:

protein_accession:HMDBP01699

name:Exostosin-1

uniprot_id:Q16394

gene_name:EXT1

protein_type:Enzyme

91:

protein_accession:HMDBP01700

name:Hyaluronan synthase 1

uniprot_id:Q92839

gene_name:HAS1

protein_type:Unknown

92:

protein_accession:HMDBP01701

name:Exostosin-like 3

uniprot_id:O43909

gene_name:EXTL3

protein_type:Enzyme

93:

protein_accession:HMDBP01702

name:Exostosin-2

uniprot_id:Q93063

gene_name:EXT2

protein_type:Enzyme

94:

protein_accession:HMDBP01703

name:Exostosin-like 1

uniprot_id:Q92935

gene_name:EXTL1

protein_type:Enzyme

95:

protein_accession:HMDBP01704

name:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase

uniprot_id:O43505

gene_name:B3GNT1

protein_type:Enzyme

96:

protein_accession:HMDBP01705

name:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

uniprot_id:Q09328

gene_name:MGAT5

protein_type:Enzyme

97:

protein_accession:HMDBP01707

name:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

uniprot_id:O15294

gene_name:OGT

protein_type:Enzyme

98:

protein_accession:HMDBP01708

name:Hyaluronan synthase 3

uniprot_id:O00219

gene_name:HAS3

protein_type:Unknown

99:

protein_accession:HMDBP01709

name:Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

uniprot_id:Q09327

gene_name:MGAT3

protein_type:Enzyme

100:

protein_accession:HMDBP01874

name:Hyaluronan synthase 2

uniprot_id:Q92819

gene_name:HAS2

protein_type:Unknown

101:

protein_accession:HMDBP02576

name:Uridine-cytidine kinase 2

uniprot_id:Q9BZX2

gene_name:UCK2

protein_type:Unknown

102:

protein_accession:HMDBP02885

name:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B

uniprot_id:Q06430

gene_name:GCNT2

protein_type:Enzyme

103:

protein_accession:HMDBP02959

name:Beta-1,4-galactosyltransferase 7

uniprot_id:Q9UBV7

gene_name:B4GALT7

protein_type:Unknown

104:

protein_accession:HMDBP02961

name:Chondroitin sulfate glucuronyltransferase

uniprot_id:Q9P2E5

gene_name:CHPF2

protein_type:Enzyme

105:

protein_accession:HMDBP03011

name:Polypeptide N-acetylgalactosaminyltransferase 13

uniprot_id:Q68VI8

gene_name:GALNT13

protein_type:Enzyme

106:

protein_accession:HMDBP03197

name:Chondroitin sulfate N-acetylgalactosaminyltransferase 2

uniprot_id:Q8N6G5

gene_name:CSGALNACT2

protein_type:Enzyme

107:

protein_accession:HMDBP03208

name:ENTPD4 protein

uniprot_id:Q8NE73

gene_name:ENTPD4

protein_type:Enzyme

108:

protein_accession:HMDBP03225

name:Beta-1,3-N-acetylglucosaminyltransferase bGnT-2

uniprot_id:Q9NY97

gene_name:bGnT-2

protein_type:Enzyme

109:

protein_accession:HMDBP03281

name:Beta-1,3-galactosyltransferase 6

uniprot_id:Q96L58

gene_name:B3GALT6

protein_type:Unknown

110:

protein_accession:HMDBP05284

name:Polypeptide N-acetylgalactosaminyltransferase 9

uniprot_id:Q9HCQ5

gene_name:GALNT9

protein_type:Unknown

111:

protein_accession:HMDBP06250

name:Exostosin-like 2

uniprot_id:Q9UBQ6

gene_name:EXTL2

protein_type:Enzyme

112:

protein_accession:HMDBP06336

name:Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

uniprot_id:Q9UM21

gene_name:MGAT4A

protein_type:Enzyme

113:

protein_accession:HMDBP06337

name:Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

uniprot_id:Q9UQ53

gene_name:MGAT4B

protein_type:Enzyme

114:

protein_accession:HMDBP06380

name:Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

uniprot_id:Q9BYG0

gene_name:B3GNT5

protein_type:Enzyme

115:

protein_accession:HMDBP06975

name:Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

uniprot_id:Q9NS00

gene_name:C1GALT1

protein_type:Unknown

116:

protein_accession:HMDBP07258

name:Beta-1,4-galactosyltransferase 6

uniprot_id:Q9UBX8

gene_name:B4GALT6

protein_type:Unknown

117:

protein_accession:HMDBP07348

name:UDP-glucuronosyltransferase 2A3

uniprot_id:Q6UWM9

gene_name:UGT2A3

protein_type:Enzyme

118:

protein_accession:HMDBP07407

name:Ribonucleoside-diphosphate reductase subunit M2 B

uniprot_id:Q7LG56

gene_name:RRM2B

protein_type:Unknown

119:

protein_accession:HMDBP07409

name:UMP-CMP kinase 2, mitochondrial

uniprot_id:Q5EBM0

gene_name:CMPK2

protein_type:Enzyme

120:

protein_accession:HMDBP07410

name:Uridine-cytidine kinase-like 1

uniprot_id:Q9NWZ5

gene_name:UCKL1

protein_type:Enzyme

121:

protein_accession:HMDBP07670

name:Ectonucleoside triphosphate diphosphohydrolase 8

uniprot_id:Q5MY95

gene_name:ENTPD8

protein_type:Unknown

122:

protein_accession:HMDBP07711

name:Polypeptide N-acetylgalactosaminyltransferase-like 6

uniprot_id:Q49A17

gene_name:GALNTL6

protein_type:Unknown

123:

protein_accession:HMDBP07712

name:Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5

uniprot_id:Q7Z4T8

gene_name:GALNTL5

protein_type:Unknown

124:

protein_accession:HMDBP08852

name:Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

uniprot_id:Q8WZA1

gene_name:POMGNT1

protein_type:Unknown

125:

protein_accession:HMDBP09151

name:Beta-1,4-N-acetylgalactosaminyltransferase 3

uniprot_id:Q6L9W6

gene_name:B4GALNT3

protein_type:Enzyme

126:

protein_accession:HMDBP09173

name:N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1

uniprot_id:Q76KP1

gene_name:B4GALNT4

protein_type:Enzyme

127:

protein_accession:HMDBP09238

name:HCG2039726, isoform CRA_f

uniprot_id:Q5DT02

gene_name:UGT1A10

protein_type:Enzyme

128:

protein_accession:HMDBP09239

name:HCG2039726, isoform CRA_e

uniprot_id:Q5DSZ6

gene_name:UGT1A8

protein_type:Enzyme

129:

protein_accession:HMDBP09240

name:UDP glycosyltransferase 1 family polypeptide A7

uniprot_id:Q5DSZ7

gene_name:UGT1A7

protein_type:Enzyme

130:

protein_accession:HMDBP09393

name:Pp-GalNAc-transferase 20

uniprot_id:Q2L4S5

gene_name:GALNT20

protein_type:Enzyme

131:

protein_accession:HMDBP11564

name:UDP-N-acetylglucosamine transferase subunit ALG13 homolog

uniprot_id:Q9NP73

gene_name:ALG13

protein_type:Enzyme

132:

protein_accession:HMDBP11731

name:EGF domain-specific O-linked N-acetylglucosamine transferase

uniprot_id:Q5NDL2

gene_name:EOGT

protein_type:Unknown

133:

protein_accession:HMDBP11742

name:Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

uniprot_id:Q02742

gene_name:GCNT1

protein_type:Unknown

134:

protein_accession:HMDBP11743

name:Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

uniprot_id:O95395

gene_name:GCNT3

protein_type:Unknown

135:

protein_accession:HMDBP11744

name:Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4

uniprot_id:Q9P109

gene_name:GCNT4

protein_type:Unknown

136:

protein_accession:HMDBP11751

name:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A

uniprot_id:Q8N0V5

gene_name:GCNT2

protein_type:Unknown

137:

protein_accession:HMDBP11752

name:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C

uniprot_id:Q8NFS9

gene_name:GCNT2

protein_type:Unknown

138:

protein_accession:HMDBP11757

name:Procollagen galactosyltransferase 1

uniprot_id:Q8NBJ5

gene_name:GLT25D1

protein_type:Unknown

139:

protein_accession:HMDBP11758

name:Procollagen galactosyltransferase 2

uniprot_id:Q8IYK4

gene_name:GLT25D2

protein_type:Unknown

140:

protein_accession:HMDBP11759

name:Glycosyltransferase-like domain-containing protein 2

uniprot_id:Q8NAT1

gene_name:GTDC2

protein_type:Unknown

141:

protein_accession:HMDBP11771

name:Glucoside xylosyltransferase 1

uniprot_id:Q4G148

gene_name:GXYLT1

protein_type:Unknown

142:

protein_accession:HMDBP11772

name:Glucoside xylosyltransferase 2

uniprot_id:A0PJZ3

gene_name:GXYLT2

protein_type:Unknown

143:

protein_accession:HMDBP11826

name:Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

uniprot_id:P26572

gene_name:MGAT1

protein_type:Unknown

144:

protein_accession:HMDBP11827

name:Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

uniprot_id:Q9UBM8

gene_name:MGAT4C

protein_type:Unknown

145:

protein_accession:HMDBP11828

name:Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

uniprot_id:Q3V5L5

gene_name:MGAT5B

protein_type:Unknown

146:

protein_accession:HMDBP11852

name:Nucleoside diphosphate kinase homolog 5

uniprot_id:P56597

gene_name:NME5

protein_type:Unknown

147:

protein_accession:HMDBP11996

name:UDP-glucuronosyltransferase 3A1

uniprot_id:Q6NUS8

gene_name:UGT3A1

protein_type:Unknown

148:

protein_accession:HMDBP11997

name:UDP-glucuronosyltransferase 3A2

uniprot_id:Q3SY77

gene_name:UGT3A2

protein_type:Unknown

149:

protein_accession:HMDBP12008

name:Xyloside xylosyltransferase 1

uniprot_id:Q8NBI6

gene_name:XXYLT1

protein_type:Unknown

蛋白质结合
1:

reference_text:Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762.

pubmed_id:19212411

2:

reference_text:Brouwer A, Morse DC, Lans MC, Schuur AG, Murk AJ, Klasson-Wehler E, Bergman A, Visser TJ: Interactions of persistent environmental organohalogens with the thyroid hormone system: mechanisms and possible consequences for animal and human health. Toxicol Ind Health. 1998 Jan-Apr;14(1-2):59-84.

pubmed_id:9460170

3:

reference_text:Kamisako T, Kobayashi Y, Takeuchi K, Ishihara T, Higuchi K, Tanaka Y, Gabazza EC, Adachi Y: Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance. J Gastroenterol. 2000;35(9):659-64.

pubmed_id:11023036

4:

reference_text:Syme MR, Paxton JW, Keelan JA: Drug transfer and metabolism by the human placenta. Clin Pharmacokinet. 2004;43(8):487-514.

pubmed_id:15170365

5:

reference_text:Collier AC, Tingle MD, Paxton JW, Mitchell MD, Keelan JA: Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption. Hum Reprod. 2002 Oct;17(10):2564-72.

pubmed_id:12351530

6:

reference_text:Morrone FB, Jacques-Silva MC, Horn AP, Bernardi A, Schwartsmann G, Rodnight R, Lenz G: Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines. J Neurooncol. 2003 Sep;64(3):211-8.

pubmed_id:14558596

7:

reference_text:Rise A: [Drugs and the fetus]. Tidsskr Nor Laegeforen. 1976 Jan 10;96(1):41-2.

pubmed_id:1257952

8:

reference_text:Court MH, Greenblatt DJ: Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms. Pharmacogenetics. 2000 Jun;10(4):355-69. doi: 10.1097/00008571-200006000-00009.

pubmed_id:10862526

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