创建日期
2005-11-16 15:48:42 UTC
更新日期
2021-09-14 15:39:00 UTC
描述
Uridine triphosphate, also known as 5'-UTP or UTP, belongs to the class of organic compounds known as pyrimidine ribonucleoside triphosphates. These are pyrimidine ribobucleotides with triphosphate group linked to the ribose moiety. More specifically, UTP is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1′ carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5′ position. Uridine triphosphate exists in all living species, ranging from bacteria to plants to humans. The main role of UTP is as substrate for the synthesis of RNA during transcription. UTP is the precursor for the production of CTP via the enzyme known as CTP Synthetase. UTP can be biosynthesized from UDP by the enzyme known as nucleoside diphosphate kinase by using phosphate group from ATP. UTP also has the role of a source of energy or an activator of substrates in a variety of metabolic reactions. For instance UTP can be used to activate Glucose-1-phosphate, leading to the formation of UDP-glucose and inorganic phosphate. The resulting UDP-glucose can be used in the synthesis of glycogen. UTP is also used in the metabolism of galactose, where the activated form of galactose, called UDP-galactose can be converted to UDP-glucose. UDP-glucuronate, another product of UTP reacting with glucuronic acid, is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid (except in primates and guinea pigs).
同义词
1:5'-UTP
2:H4UTP
3:Uridine 5'-triphosphate
4:Uridine 5'-triphosphoric acid
5:Uridine triphosphoric acid
6:Uridine mono(tetrahydrogen triphosphate)
7:Uteplex
8:UTP
9:MG UTP
10:Magnesium UTP
11:Magnesium uridine triphosphate
12:Triphosphate, uridine
13:MG-UTP
14:Triphosphate, magnesium uridine
15:UTP, Magnesium
化学名称
({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
传统名称
uridine 5'-triphosphoric acid
代谢物结构字符串
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
inchi标识符
InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
印记键
PGAVKCOVUIYSFO-XVFCMESISA-N
分类学
description: belongs to the class of organic compounds known as pyrimidine ribonucleoside triphosphates. These are pyrimidine ribobucleotides with triphosphate group linked to the ribose moiety.
description:Pyrimidine ribonucleoside triphosphates
kingdom:Organic compounds
super_class:Nucleosides, nucleotides, and analogues
class:Pyrimidine nucleotides
sub_class:Pyrimidine ribonucleotides
molecular_framework:Aromatic heteromonocyclic compounds
1:1,2-diols
2:Azacyclic compounds
3:Glycosylamines
4:Heteroaromatic compounds
5:Hydrocarbon derivatives
6:Hydropyrimidines
7:Hydroxypyrimidines
8:Monoalkyl phosphates
9:Monosaccharide phosphates
10:Organic oxides
11:Organonitrogen compounds
12:Organopnictogen compounds
13:Oxacyclic compounds
14:Pentose phosphates
15:Pyrimidones
16:Secondary alcohols
17:Tetrahydrofurans
18:1,2-diol
19:Alcohol
20:Alkyl phosphate
21:Aromatic heteromonocyclic compound
22:Azacycle
23:Glycosyl compound
24:Heteroaromatic compound
25:Hydrocarbon derivative
26:Hydropyrimidine
27:Hydroxypyrimidine
28:Monoalkyl phosphate
29:Monosaccharide
30:Monosaccharide phosphate
31:N-glycosyl compound
32:Organic nitrogen compound
33:Organic oxide
34:Organic oxygen compound
35:Organic phosphoric acid derivative
36:Organoheterocyclic compound
37:Organonitrogen compound
38:Organooxygen compound
39:Organopnictogen compound
40:Oxacycle
41:Pentose phosphate
42:Pentose-5-phosphate
43:Phosphoric acid ester
44:Pyrimidine
45:Pyrimidine ribonucleoside triphosphate
46:Pyrimidone
47:Secondary alcohol
48:Tetrahydrofuran
49:Ribonucleotides
50:pyrimidine ribonucleoside 5'-triphosphate
51:uridine 5'-phosphate
本体论
term:Disposition
definition:A concept that describes the origin of a chemical, its location within an organism, or its route of exposure.
parent_id:
level:1
type:parent
term:Route of exposure
definition:A mean by which a chemical agent comes in contact with an organism, either under intended or unintended circumstances.
parent_id:7724
*level:2
type:parent
term:Enteral
definition:Chemical exposure via the alimentary canal (mouth to anus).
parent_id:7743
**level:3
type:parent
term:Ingestion
definition:Chemical exposure facilitated by entry through the mouth.
parent_id:7744
***level:4
type:child
synonym:Digestion
term:Source
definition:Natural or synthetic origin of a chemical.
parent_id:7724
*level:2
type:parent
term:Endogenous
definition:
parent_id:7735
**level:3
type:child
term:Food
definition:
parent_id:7735
**level:3
type:child
term:Biological
definition:A living organism (species or a higher taxonomy rank), in which a chemical can be found.
parent_id:7735
**level:3
type:parent
term:Plant
definition:A living organism belonging to the kingdom plantea. typically, it grows in a permanent site, absorbs water and inorganic substances through its roots, and synthesizes nutrients in its leaves by photosynthesis using the green pigment chlorophyll. examples incude trees, shrubs, herbs, grasses, ferns, and mosses.
parent_id:7736
***level:4
type:parent
synonym:Flora
term:Animal
definition:A living organism belonging to the kingdom animalia. it feeds on organic matter, typically having specialized sense organs and nervous system and able to respond rapidly to stimuli.
parent_id:7736
***level:4
type:child
synonym:Fauna
term:Biological location
definition:The physiological origin within an organism, including anatomical compnents, biofluids and excreta.
parent_id:7724
*level:2
type:parent
term:Biofluid and excreta
definition:A liquid, semi-solid or solid material originating in the body.
parent_id:7725
**level:3
type:parent
term:Saliva
definition:The watery fluid in the mouth made by the salivary glands. saliva moistens food to help digestion and it helps protect the mouth against infections. (nci).
parent_id:7731
***level:4
type:child
term:Subcellular
definition:An anatomical organizational level including a component within a biological cell .
parent_id:7725
**level:3
type:parent
term:Cytoplasm
definition:The portion of the cell contained within the plasma membrane but excluding the nucleus.
parent_id:7730
***level:4
type:child
synonym:Cytoplasma
term:Mitochondria
definition:
parent_id:7730
***level:4
type:child
term:Nucleus
definition:A body within the cell, surrounded by a membrane, within which lie the chromosomes, one or more nucleoli, combined with proteins, and exhibits mitosis. (NCI)
parent_id:7730
***level:4
type:child
synonym:Cell nucleus
synonym:Nucleic
term:Cell and elements
definition:An anatomical organizational level comprising of a single cell (or a fragment in some exceptions). a cell is defined by its type or function. it is the smallest unit of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid.
parent_id:7725
**level:3
type:parent
term:Extracellular
definition:The space external to the outermost structure of a cell.
parent_id:7732
***level:4
type:child
synonym:Extracellular region
term:Process
definition:Biological or chemical events, or a series thereof, leading to a known function or end-product.
parent_id:
level:1
type:parent
term:Naturally occurring process
definition:Naturally-occurring molecular events or a series thereof, leading to a known function or end-product.
parent_id:7659
*level:2
type:parent
term:Biological process
definition:Biological or chemical events or a series thereof, leading to a known function or end-product within an organism.
parent_id:7660
**level:3
type:parent
term:Biochemical pathway
definition:A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
parent_id:7661
***level:4
type:parent
term:Role
definition:The purpose or function assumed by a chemical, either naturally or as intended by humans .
parent_id:
level:1
type:parent
term:Industrial application
definition:The assumed function of a chemical utilized by human.
parent_id:7671
*level:2
type:parent
term:Pharmaceutical industry
definition:A pharmacologic activity for which a chemical substance is utilized owing to its biological role.
parent_id:7678
**level:3
type:parent
term:Pharmaceutical
definition:
parent_id:7679
***level:4
type:child
预测性质
1:
kind:logp
value:-0.07
source:ALOGPS
2:
kind:logs
value:-1.76
source:ALOGPS
3:
kind:solubility
value:8.37 g/L
source:ALOGPS
4:
kind:logp
value:-3.4
source:ChemAxon
5:
kind:pka_strongest_acidic
value:0.9
source:ChemAxon
6:
kind:pka_strongest_basic
value:-3.7
source:ChemAxon
7:
kind:iupac
value:({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
source:ChemAxon
8:
kind:average_mass
value:484.1411
source:ChemAxon
9:
kind:mono_mass
value:483.968527356
source:ChemAxon
10:
kind:smiles
value:O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
source:ChemAxon
11:
kind:formula
value:C9H15N2O15P3
source:ChemAxon
12:
kind:inchi
value:InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
source:ChemAxon
13:
kind:inchikey
value:PGAVKCOVUIYSFO-XVFCMESISA-N
source:ChemAxon
14:
kind:polar_surface_area
value:258.92
source:ChemAxon
15:
kind:refractivity
value:85.18
source:ChemAxon
16:
kind:polarizability
value:35.38
source:ChemAxon
17:
kind:rotatable_bond_count
value:8
source:ChemAxon
18:
kind:acceptor_count
value:12
source:ChemAxon
19:
kind:donor_count
value:7
source:ChemAxon
20:
kind:physiological_charge
value:-3
source:ChemAxon
21:
kind:formal_charge
value:0
source:ChemAxon
22:
kind:number_of_rings
value:2
source:ChemAxon
23:
kind:bioavailability
value:No
source:ChemAxon
24:
kind:rule_of_five
value:No
source:ChemAxon
25:
kind:ghose_filter
value:No
source:ChemAxon
26:
kind:veber_rule
value:No
source:ChemAxon
27:
kind:mddr_like_rule
value:No
source:ChemAxon
1:
type:Specdb::CMs
spectrum_id:12936
2:
type:Specdb::CMs
spectrum_id:37402
3:
type:Specdb::CMs
spectrum_id:133766
4:
type:Specdb::CMs
spectrum_id:141500
5:
type:Specdb::NmrOneD
spectrum_id:4844
6:
type:Specdb::NmrOneD
spectrum_id:4845
7:
type:Specdb::NmrOneD
spectrum_id:143310
8:
type:Specdb::NmrOneD
spectrum_id:143311
9:
type:Specdb::NmrOneD
spectrum_id:143312
10:
type:Specdb::NmrOneD
spectrum_id:143313
11:
type:Specdb::NmrOneD
spectrum_id:143314
12:
type:Specdb::NmrOneD
spectrum_id:143315
13:
type:Specdb::NmrOneD
spectrum_id:143316
14:
type:Specdb::NmrOneD
spectrum_id:143317
15:
type:Specdb::NmrOneD
spectrum_id:143318
16:
type:Specdb::NmrOneD
spectrum_id:143319
17:
type:Specdb::NmrOneD
spectrum_id:143320
18:
type:Specdb::NmrOneD
spectrum_id:143321
19:
type:Specdb::NmrOneD
spectrum_id:143322
20:
type:Specdb::NmrOneD
spectrum_id:143323
21:
type:Specdb::NmrOneD
spectrum_id:143324
22:
type:Specdb::NmrOneD
spectrum_id:143325
23:
type:Specdb::NmrOneD
spectrum_id:143326
24:
type:Specdb::NmrOneD
spectrum_id:143327
25:
type:Specdb::NmrOneD
spectrum_id:143328
26:
type:Specdb::NmrOneD
spectrum_id:143329
27:
type:Specdb::MsMs
spectrum_id:28958
28:
type:Specdb::MsMs
spectrum_id:28959
29:
type:Specdb::MsMs
spectrum_id:28960
30:
type:Specdb::MsMs
spectrum_id:35516
31:
type:Specdb::MsMs
spectrum_id:35517
32:
type:Specdb::MsMs
spectrum_id:35518
33:
type:Specdb::MsMs
spectrum_id:2236078
34:
type:Specdb::MsMs
spectrum_id:2237288
35:
type:Specdb::MsMs
spectrum_id:2238179
36:
type:Specdb::MsMs
spectrum_id:2239412
37:
type:Specdb::MsMs
spectrum_id:2240294
38:
type:Specdb::MsMs
spectrum_id:2241396
39:
type:Specdb::MsMs
spectrum_id:2834277
40:
type:Specdb::MsMs
spectrum_id:2834278
41:
type:Specdb::MsMs
spectrum_id:2834279
42:
type:Specdb::MsMs
spectrum_id:2871878
43:
type:Specdb::MsMs
spectrum_id:2871879
44:
type:Specdb::MsMs
spectrum_id:2871880
生物学性质
1:
cellular:(1):Cytoplasm
cellular:(2):Extracellular
cellular:(3):Mitochondria
cellular:(4):Nucleus
2:
biospecimen:(1):Saliva
3:
4:
[1]:
name:Amikacin Action Pathway
smpdb_id:SMP00253
kegg_map_id:
[2]:
name:Amino Sugar Metabolism
smpdb_id:SMP00045
kegg_map_id:map00520
[3]:
name:Arbekacin Action Pathway
smpdb_id:SMP00713
kegg_map_id:
[4]:
name:Azithromycin Action Pathway
smpdb_id:SMP00247
kegg_map_id:
[5]:
name:Beta Ureidopropionase Deficiency
smpdb_id:SMP00172
kegg_map_id:
[6]:
name:Chloramphenicol Action Pathway
smpdb_id:SMP00729
kegg_map_id:
[7]:
name:Clarithromycin Action Pathway
smpdb_id:SMP00248
kegg_map_id:
[8]:
name:Clindamycin Action Pathway
smpdb_id:SMP00249
kegg_map_id:
[9]:
name:Clomocycline Action Pathway
smpdb_id:SMP00262
kegg_map_id:
[10]:
name:Congenital disorder of glycosylation CDG-IId
smpdb_id:SMP00579
kegg_map_id:
[11]:
name:Demeclocycline Action Pathway
smpdb_id:SMP00290
kegg_map_id:
[12]:
name:Dihydropyrimidinase Deficiency
smpdb_id:SMP00178
kegg_map_id:
[13]:
name:DNA Replication Fork
smpdb_id:SMP00477
kegg_map_id:
[14]:
name:Doxycycline Action Pathway
smpdb_id:SMP00291
kegg_map_id:
[15]:
name:Erythromycin Action Pathway
smpdb_id:SMP00250
kegg_map_id:
[16]:
name:G(M2)-Gangliosidosis: Variant B, Tay-sachs disease
smpdb_id:SMP00534
kegg_map_id:
[17]:
name:Galactose Metabolism
smpdb_id:SMP00043
kegg_map_id:map00052
[18]:
name:Galactosemia
smpdb_id:SMP00182
kegg_map_id:
[19]:
name:Galactosemia II (GALK)
smpdb_id:SMP00495
kegg_map_id:
[20]:
name:Galactosemia III
smpdb_id:SMP00496
kegg_map_id:
[21]:
name:Gentamicin Action Pathway
smpdb_id:SMP00254
kegg_map_id:
[22]:
name:GLUT-1 deficiency syndrome
smpdb_id:SMP00580
kegg_map_id:
[23]:
name:Glycogen synthetase deficiency
smpdb_id:SMP00552
kegg_map_id:
[24]:
name:Glycogenosis, Type III. Cori disease, Debrancher glycogenosis
smpdb_id:SMP00553
kegg_map_id:
[25]:
name:Glycogenosis, Type IV. Amylopectinosis, Anderson disease
smpdb_id:SMP00554
kegg_map_id:
[26]:
name:Glycogenosis, Type VI. Hers disease
smpdb_id:SMP00555
kegg_map_id:
[27]:
name:Josamycin Action Pathway
smpdb_id:SMP00731
kegg_map_id:
[28]:
name:Kanamycin Action Pathway
smpdb_id:SMP00255
kegg_map_id:
[29]:
name:Lactose Synthesis
smpdb_id:SMP00444
kegg_map_id:
[30]:
name:Lamivudine Metabolism Pathway
smpdb_id:SMP00649
kegg_map_id:
[31]:
name:Lincomycin Action Pathway
smpdb_id:SMP00728
kegg_map_id:
[32]:
name:Lymecycline Action Pathway
smpdb_id:SMP00295
kegg_map_id:
[33]:
name:Methacycline Action Pathway
smpdb_id:SMP00727
kegg_map_id:
[34]:
name:Minocycline Action Pathway
smpdb_id:SMP00292
kegg_map_id:
[35]:
name:MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
smpdb_id:SMP00202
kegg_map_id:
[36]:
name:Mucopolysaccharidosis VI. Sly syndrome
smpdb_id:SMP00556
kegg_map_id:
[37]:
name:Neomycin Action Pathway
smpdb_id:SMP00256
kegg_map_id:
[38]:
name:Netilmicin Action Pathway
smpdb_id:SMP00257
kegg_map_id:
[39]:
name:Nucleotide Sugars Metabolism
smpdb_id:SMP00010
kegg_map_id:map00520
[40]:
name:Oxytetracycline Action Pathway
smpdb_id:SMP00293
kegg_map_id:
[41]:
name:Paromomycin Action Pathway
smpdb_id:SMP00714
kegg_map_id:
[42]:
name:Pyrimidine metabolism
smpdb_id:
kegg_map_id:map00240
[43]:
name:Rolitetracycline Action Pathway
smpdb_id:SMP00726
kegg_map_id:
[44]:
name:Roxithromycin Action Pathway
smpdb_id:SMP00251
kegg_map_id:
[45]:
name:Salla Disease/Infantile Sialic Acid Storage Disease
smpdb_id:SMP00240
kegg_map_id:
[46]:
name:Sialuria or French Type Sialuria
smpdb_id:SMP00216
kegg_map_id:
[47]:
name:Spectinomycin Action Pathway
smpdb_id:SMP00258
kegg_map_id:
[48]:
name:Starch and Sucrose Metabolism
smpdb_id:SMP00058
kegg_map_id:map00500
[49]:
name:Streptomycin Action Pathway
smpdb_id:SMP00259
kegg_map_id:
[50]:
name:Sucrase-isomaltase deficiency
smpdb_id:SMP00557
kegg_map_id:
[51]:
name:Tay-Sachs Disease
smpdb_id:SMP00390
kegg_map_id:
[52]:
name:Telithromycin Action Pathway
smpdb_id:SMP00252
kegg_map_id:
[53]:
name:Tetracycline Action Pathway
smpdb_id:SMP00294
kegg_map_id:
[54]:
name:Tigecycline Action Pathway
smpdb_id:SMP00712
kegg_map_id:
[55]:
name:Tobramycin Action Pathway
smpdb_id:SMP00711
kegg_map_id:
[56]:
name:Transcription/Translation
smpdb_id:SMP00019
kegg_map_id:
[57]:
name:Troleandomycin Action Pathway
smpdb_id:SMP00730
kegg_map_id:
[58]:
name:UMP Synthase Deficiency (Orotic Aciduria)
smpdb_id:SMP00219
kegg_map_id:
正常浓度
1:
biospecimen:Saliva
concentration_value:1.02 +/- 0.67
concentration_units:uM
subject_age:Adult (>18 years old)
subject_sex:Both
subject_condition:Normal
维基百科编号
Uridine triphosphate
综合参考
Kenner, G. W.; Todd, A. R.; Webb, R. F.; Weymouth, F. J. Nucleotides. XXVIII. Synthesis of uridine 5'-triphosphate. Journal of the Chemical Society (1954), 46-52 2288-93.
一般参考
1:
protein_accession:HMDBP00084
name:Ectonucleoside triphosphate diphosphohydrolase 1
uniprot_id:P49961
gene_name:ENTPD1
protein_type:Unknown
2:
protein_accession:HMDBP00085
name:Soluble calcium-activated nucleotidase 1
uniprot_id:Q8WVQ1
gene_name:CANT1
protein_type:Unknown
3:
protein_accession:HMDBP00086
name:Ectonucleoside triphosphate diphosphohydrolase 3
uniprot_id:O75355
gene_name:ENTPD3
protein_type:Unknown
4:
protein_accession:HMDBP00105
name:Uridine-cytidine kinase 1
uniprot_id:Q9HA47
gene_name:UCK1
protein_type:Unknown
5:
protein_accession:HMDBP00106
name:Nucleoside diphosphate kinase, mitochondrial
uniprot_id:O00746
gene_name:NME4
protein_type:Unknown
6:
protein_accession:HMDBP00109
name:Nucleoside diphosphate kinase A
uniprot_id:P15531
gene_name:NME1
protein_type:Unknown
7:
protein_accession:HMDBP00110
name:Nucleoside diphosphate kinase 7
uniprot_id:Q9Y5B8
gene_name:NME7
protein_type:Unknown
8:
protein_accession:HMDBP00112
name:Nucleoside diphosphate kinase B
uniprot_id:P22392
gene_name:NME2
protein_type:Unknown
9:
protein_accession:HMDBP00113
name:Nucleoside diphosphate kinase 3
uniprot_id:Q13232
gene_name:NME3
protein_type:Unknown
10:
protein_accession:HMDBP00114
name:Nucleoside diphosphate kinase 6
uniprot_id:O75414
gene_name:NME6
protein_type:Unknown
11:
protein_accession:HMDBP00431
name:Inosine triphosphate pyrophosphatase
uniprot_id:Q9BY32
gene_name:ITPA
protein_type:Unknown
12:
protein_accession:HMDBP00573
name:GTP:AMP phosphotransferase, mitochondrial
uniprot_id:Q9UIJ7
gene_name:AK3
protein_type:Enzyme
13:
protein_accession:HMDBP00621
name:Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
uniprot_id:P50583
gene_name:NUDT2
protein_type:Unknown
14:
protein_accession:HMDBP00676
name:CTP synthase 1
uniprot_id:P17812
gene_name:CTPS1
protein_type:Unknown
15:
protein_accession:HMDBP00734
name:6-phosphofructokinase type C
uniprot_id:Q01813
gene_name:PFKP
protein_type:Unknown
16:
protein_accession:HMDBP00736
name:DNA-directed RNA polymerase III subunit RPC4
uniprot_id:P05423
gene_name:POLR3D
protein_type:Enzyme
17:
protein_accession:HMDBP00737
name:DNA-directed RNA polymerase II subunit RPB2
uniprot_id:P30876
gene_name:POLR2B
protein_type:Unknown
18:
protein_accession:HMDBP00739
name:DNA-directed RNA polymerase II subunit RPB1
uniprot_id:P24928
gene_name:POLR2A
protein_type:Unknown
19:
protein_accession:HMDBP00742
name:DNA-directed RNA polymerase, mitochondrial
uniprot_id:O00411
gene_name:POLRMT
protein_type:Enzyme
20:
protein_accession:HMDBP00743
name:DNA-directed RNA polymerase I subunit RPA2
uniprot_id:Q9H9Y6
gene_name:POLR1B
protein_type:Enzyme
21:
protein_accession:HMDBP00744
name:DNA-directed RNA polymerase III subunit RPC7
uniprot_id:O15318
gene_name:POLR3G
protein_type:Enzyme
22:
protein_accession:HMDBP00752
name:DNA-directed RNA polymerase III subunit RPC2
uniprot_id:Q9NW08
gene_name:POLR3B
protein_type:Enzyme
23:
protein_accession:HMDBP00756
name:DNA-directed RNA polymerase I subunit RPA49
uniprot_id:Q9GZS1
gene_name:POLR1E
protein_type:Enzyme
24:
protein_accession:HMDBP00758
name:6-phosphofructokinase, liver type
uniprot_id:P17858
gene_name:PFKL
protein_type:Unknown
25:
protein_accession:HMDBP00760
name:DNA-directed RNA polymerase III subunit RPC8
uniprot_id:Q9Y535
gene_name:POLR3H
protein_type:Enzyme
26:
protein_accession:HMDBP00761
name:DNA-directed RNA polymerase III subunit RPC10
uniprot_id:Q9Y2Y1
gene_name:POLR3K
protein_type:Unknown
27:
protein_accession:HMDBP00762
name:6-phosphofructokinase, muscle type
uniprot_id:P08237
gene_name:PFKM
protein_type:Unknown
28:
protein_accession:HMDBP00763
name:Pyruvate kinase isozymes M1/M2
uniprot_id:P14618
gene_name:PKM
protein_type:Unknown
29:
protein_accession:HMDBP00765
name:Pyruvate kinase isozymes R/L
uniprot_id:P30613
gene_name:PKLR
protein_type:Unknown
30:
protein_accession:HMDBP01074
name:UTP--glucose-1-phosphate uridylyltransferase
uniprot_id:Q16851
gene_name:UGP2
protein_type:Enzyme
31:
protein_accession:HMDBP01079
name:UDP-N-acetylhexosamine pyrophosphorylase
uniprot_id:Q16222
gene_name:UAP1
protein_type:Enzyme
32:
protein_accession:HMDBP02576
name:Uridine-cytidine kinase 2
uniprot_id:Q9BZX2
gene_name:UCK2
protein_type:Unknown
33:
protein_accession:HMDBP03298
name:CAD protein
uniprot_id:P27708
gene_name:CAD
protein_type:Unknown
34:
protein_accession:HMDBP04074
name:CTP synthase 2
uniprot_id:Q9NRF8
gene_name:CTPS2
protein_type:Enzyme
35:
protein_accession:HMDBP07410
name:Uridine-cytidine kinase-like 1
uniprot_id:Q9NWZ5
gene_name:UCKL1
protein_type:Enzyme
36:
protein_accession:HMDBP07670
name:Ectonucleoside triphosphate diphosphohydrolase 8
uniprot_id:Q5MY95
gene_name:ENTPD8
protein_type:Unknown
37:
protein_accession:HMDBP09344
name:DNA-directed RNA polymerase III subunit RPC1
uniprot_id:O14802
gene_name:POLR3A
protein_type:Enzyme
38:
protein_accession:HMDBP09345
name:DNA-directed RNA polymerase I subunit RPA1
uniprot_id:O95602
gene_name:POLR1A
protein_type:Enzyme
39:
protein_accession:HMDBP09346
name:Zinc ribbon domain containing 1
uniprot_id:Q2L6J2
gene_name:ZNRD1
protein_type:Enzyme
40:
protein_accession:HMDBP09347
name:DNA-directed RNA polymerases I and III subunit RPAC2
uniprot_id:Q9Y2S0
gene_name:POLR1D
protein_type:Enzyme
41:
protein_accession:HMDBP09348
name:DNA-directed RNA polymerase
uniprot_id:Q7Z3R8
gene_name:DKFZp686D10173
protein_type:Enzyme
42:
protein_accession:HMDBP09349
name:DNA-directed RNA polymerase III subunit RPC7-like
uniprot_id:Q9BT43
gene_name:POLR3GL
protein_type:Enzyme
43:
protein_accession:HMDBP09350
name:POLR1C protein
uniprot_id:Q96HT3
gene_name:POLR1C
protein_type:Enzyme
44:
protein_accession:HMDBP11852
name:Nucleoside diphosphate kinase homolog 5
uniprot_id:P56597
gene_name:NME5
protein_type:Unknown
45:
protein_accession:HMDBP11909
name:DNA-directed RNA polymerase I subunit RPA12
uniprot_id:Q9P1U0
gene_name:ZNRD1
protein_type:Unknown
46:
protein_accession:HMDBP11910
name:DNA-directed RNA polymerase I subunit RPA43
uniprot_id:Q3B726
gene_name:TWISTNB
protein_type:Unknown
47:
protein_accession:HMDBP11911
name:DNA-directed RNA polymerases I, II, and III subunit RPABC1
uniprot_id:P19388
gene_name:POLR2E
protein_type:Unknown
48:
protein_accession:HMDBP11912
name:DNA-directed RNA polymerases I, II, and III subunit RPABC2
uniprot_id:P61218
gene_name:POLR2F
protein_type:Unknown
49:
protein_accession:HMDBP11913
name:DNA-directed RNA polymerases I, II, and III subunit RPABC3
uniprot_id:P52434
gene_name:POLR2H
protein_type:Unknown
50:
protein_accession:HMDBP11914
name:DNA-directed RNA polymerases I, II, and III subunit RPABC4
uniprot_id:P53803
gene_name:POLR2K
protein_type:Unknown
51:
protein_accession:HMDBP11915
name:DNA-directed RNA polymerases I, II, and III subunit RPABC5
uniprot_id:P62875
gene_name:POLR2L
protein_type:Unknown
52:
protein_accession:HMDBP11916
name:DNA-directed RNA polymerases I and III subunit RPAC1
uniprot_id:O15160
gene_name:POLR1C
protein_type:Unknown
53:
protein_accession:HMDBP11918
name:DNA-directed RNA polymerase II subunit RPB11-a
uniprot_id:P52435
gene_name:POLR2J
protein_type:Unknown
54:
protein_accession:HMDBP11919
name:DNA-directed RNA polymerase II subunit RPB11-b1
uniprot_id:Q9GZM3
gene_name:POLR2J2
protein_type:Unknown
55:
protein_accession:HMDBP11920
name:DNA-directed RNA polymerase II subunit RPB3
uniprot_id:P19387
gene_name:POLR2C
protein_type:Unknown
56:
protein_accession:HMDBP11921
name:DNA-directed RNA polymerase II subunit RPB4
uniprot_id:O15514
gene_name:POLR2D
protein_type:Unknown
57:
protein_accession:HMDBP11922
name:DNA-directed RNA polymerase II subunit RPB7
uniprot_id:P62487
gene_name:POLR2G
protein_type:Unknown
58:
protein_accession:HMDBP11923
name:DNA-directed RNA polymerase II subunit RPB9
uniprot_id:P36954
gene_name:POLR2I
protein_type:Unknown
59:
protein_accession:HMDBP11924
name:DNA-directed RNA polymerase III subunit RPC3
uniprot_id:Q9BUI4
gene_name:POLR3C
protein_type:Unknown
60:
protein_accession:HMDBP11925
name:DNA-directed RNA polymerase III subunit RPC5
uniprot_id:Q9NVU0
gene_name:POLR3E
protein_type:Unknown
61:
protein_accession:HMDBP11926
name:DNA-directed RNA polymerase III subunit RPC6
uniprot_id:Q9H1D9
gene_name:POLR3F
protein_type:Unknown
62:
protein_accession:HMDBP11967
name:Speckle targeted PIP5K1A-regulated poly(A) polymerase
uniprot_id:Q9H6E5
gene_name:TUT1
protein_type:Unknown
63:
protein_accession:HMDBP11984
name:Terminal uridylyltransferase 4
uniprot_id:Q5TAX3
gene_name:ZCCHC11
protein_type:Unknown
64:
protein_accession:HMDBP11985
name:Terminal uridylyltransferase 7
uniprot_id:Q5VYS8
gene_name:ZCCHC6
protein_type:Unknown
65:
protein_accession:HMDBP11988
name:UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
uniprot_id:Q3KQV9
gene_name:UAP1L1
protein_type:Unknown
蛋白质结合
1:
reference_text:Kunzelmann K, Mall M: Pharmacotherapy of the ion transport defect in cystic fibrosis: role of purinergic receptor agonists and other potential therapeutics. Am J Respir Med. 2003;2(4):299-309.
pubmed_id:14719996
2:
reference_text:Erlinge D, Harnek J, van Heusden C, Olivecrona G, Jern S, Lazarowski E: Uridine triphosphate (UTP) is released during cardiac ischemia. Int J Cardiol. 2005 Apr 28;100(3):427-33.
pubmed_id:15837087
3:
reference_text:Oosterhuis GJ, Mulder AB, Kalsbeek-Batenburg E, Lambalk CB, Schoemaker J, Vermes I: Measuring apoptosis in human spermatozoa: a biological assay for semen quality? Fertil Steril. 2000 Aug;74(2):245-50.
pubmed_id:10927039
4:
reference_text:Holstege A, Manglitz D, Gerok W: Depletion of blood plasma cytidine due to increased hepatocellular salvage in D-galactosamine-treated rats. Eur J Biochem. 1984 Jun 1;141(2):339-44.
pubmed_id:6734601