版本
5.0
创建日期
2005-11-16 15:48:42 UTC
更新日期
2021-09-14 15:44:43 UTC
登录号
HMDB0000163
地位
quantified
二级访问
HMDB00163

名称
D-Maltose
描述
D-Maltose, also known as maltose, maltobiose or malt sugar, is a disaccharide formed from two units of glucose joined with an alpha (1→4) bond. Its name comes from malt, combined with the suffix '-ose' which is used in names of sugars. Maltose is a key structural motif of starch. When alpha-amylase breaks down starch, it removes two glucose units at a time, producing maltose. Maltose can be further broken down to glucose by the maltase enzyme, which catalyses the hydrolysis of the glycosidic bond. D-maltose exists in all living species, ranging from bacteria to plants to humans. Within humans, D-maltose participates in a number of enzymatic reactions. In particular, maltose can be converted into glucose; which is mediated by the enzyme maltase-glucoamylase. In addition, maltose can be converted into glucose through its interaction with the enzyme glycogen debranching enzyme. Maltose is found in high concentrations in oriental wheats and in a lower concentrations in sweet potato, grape wines, yellow pond-lilies, sunflowers, and spinach. Maltose is a component of malt, a substance which is obtained in the process of allowing grain to soften in water and germinate. It is also present in highly variable quantities in partially hydrolysed starch products like maltodextrin, corn syrup and acid-thinned starch. Maltose has a sweet taste but is only about 30–60% as sweet as sucrose, depending on the concentration.
同义词
1:4-O-alpha-D-Glucopyranosyl-alpha-D-mannopyranose

2:4-O-a-D-Glucopyranosyl-a-D-mannopyranose

3:4-O-Α-D-glucopyranosyl-α-D-mannopyranose

4:1-alpha-D-Glucopyranosyl-4-alpha-D-glucopyranose

5:1-alpha-delta-Glucopyranosyl-4-alpha-delta-glucopyranose

6:4-(alpha-D-Glucopyranosido)-alpha-glucopyranose

7:4-(alpha-D-Glucosido)-D-glucose

8:4-(alpha-delta-Glucopyranosido)-alpha-glucopyranose

9:4-(alpha-delta-Glucosido)-delta-glucose

10:4-O-a-D-Glucopyranosyl-D-glucose

11:4-O-alpha-D-Glucopyranosyl-D-glucopyranose

12:4-O-alpha-D-Glucopyranosyl-D-glucose

13:4-O-alpha-delta-Glucopyranosyl-delta-glucopyranose

14:4-O-alpha-delta-Glucopyranosyl-delta-glucose

15:Advantose 100

16:alpha-D-GLCP-(1->4)-D-GLCP

17:alpha-D-Glucopyranosyl-(1->4)-D-glucopyranose

18:alpha-D-Glucopyranosyl-(1->4)-D-glucose

19:alpha-delta-GLCP-(1->4)-delta-GLCP

20:alpha-delta-Glucopyranosyl-(1->4)-delta-glucopyranose

21:alpha-delta-Glucopyranosyl-(1->4)-delta-glucose

22:alpha-Malt sugar

23:Cextromaltose

24:D-(+)-Maltose

25:delta-(+)-Maltose

26:delta-Maltose

27:Finetose

28:Finetose F

29:Madoros

30:Malt sugar

31:Maltobiose

32:Maltodiose

33:Maltos

34:Maltose

35:Maltose HH

36:Maltose HHH

37:Maltose solution

38:Malzzucker

39:Martos-10

40:Sunmalt

41:Sunmalt S

化学式
C12H22O11
平均分子量
342.2965
等位分子量
342.116211546
化学名称
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol
传统名称
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol
CAS 登记号
69-79-4
代谢物结构字符串
OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O
inchi标识符
InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5-,6+,7-,8+,9-,10-,11+,12-/m1/s1
印记键
GUBGYTABKSRVRQ-DKBJLJRDSA-N
分类学
description: belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.

description:O-glycosyl compounds

kingdom:Organic compounds

super_class:Organic oxygen compounds

class:Organooxygen compounds

sub_class:Carbohydrates and carbohydrate conjugates

molecular_framework:Aliphatic heteromonocyclic compounds

1:Acetals

2:Disaccharides

3:Hemiacetals

4:Hydrocarbon derivatives

5:Oxacyclic compounds

6:Oxanes

7:Polyols

8:Primary alcohols

9:Secondary alcohols

10:Acetal

11:Alcohol

12:Aliphatic heteromonocyclic compound

13:Disaccharide

14:Hemiacetal

15:Hydrocarbon derivative

16:O-glycosyl compound

17:Organoheterocyclic compound

18:Oxacycle

19:Oxane

20:Polyol

21:Primary alcohol

22:Secondary alcohol

23:alpha-D-glucosyl-(1->4)-D-mannopyranose

本体论
term:Physiological effect

definition:The effect on an organism physiology, resulting from its exposure to a chemical.

parent_id:

level:1

type:parent

term:Health effect

definition:A health condition or observation associated with a stimuli or with a biological activity of a chemical.

parent_id:7693

*level:2

type:parent

term:Health condition

definition:A health effect that consists on short or long-term disease, condition, disorder, syndrome or constant abnormality.

parent_id:7694

**level:3

type:parent

term:Peritoneal dialysis

definition:

parent_id:7695

***level:4

type:child

synonym:Pd

term:Disposition

definition:A concept that describes the origin of a chemical, its location within an organism, or its route of exposure.

parent_id:

level:1

type:parent

term:Route of exposure

definition:A mean by which a chemical agent comes in contact with an organism, either under intended or unintended circumstances.

parent_id:7724

*level:2

type:parent

term:Enteral

definition:Chemical exposure via the alimentary canal (mouth to anus).

parent_id:7743

**level:3

type:parent

term:Ingestion

definition:Chemical exposure facilitated by entry through the mouth.

parent_id:7744

***level:4

type:child

synonym:Digestion

term:Source

definition:Natural or synthetic origin of a chemical.

parent_id:7724

*level:2

type:parent

term:Endogenous

definition:

parent_id:7735

**level:3

type:child

term:Food

definition:

parent_id:7735

**level:3

type:child

term:Biological

definition:A living organism (species or a higher taxonomy rank), in which a chemical can be found.

parent_id:7735

**level:3

type:parent

term:Animal

definition:A living organism belonging to the kingdom animalia. it feeds on organic matter, typically having specialized sense organs and nervous system and able to respond rapidly to stimuli.

parent_id:7736

***level:4

type:child

synonym:Fauna

term:Plant

definition:A living organism belonging to the kingdom plantea. typically, it grows in a permanent site, absorbs water and inorganic substances through its roots, and synthesizes nutrients in its leaves by photosynthesis using the green pigment chlorophyll. examples incude trees, shrubs, herbs, grasses, ferns, and mosses.

parent_id:7736

***level:4

type:parent

synonym:Flora

term:Biological location

definition:The physiological origin within an organism, including anatomical compnents, biofluids and excreta.

parent_id:7724

*level:2

type:parent

term:Tissue and substructures

definition:An anatomical organizational level including multiple cells yet not comprising a complete organ .

parent_id:7725

**level:3

type:parent

term:Placenta

definition:An organ present in some vertebrates during embryonic gestation that surrounds the fetus and provides it with nutrients and oxygen, facilitates gas and waste exchange between the fetus and mother, and provides parasitic cloaking from the mother's immune system by excretion of neurokinin b. (nci).

parent_id:7729

***level:4

type:child

term:Organ and components

definition:An anatomical organizational level including multiple tissues or substructures, which enables a common biological function.

parent_id:7725

**level:3

type:parent

term:Liver

definition:An abdominal organ that has variable lobation which are composed mainly of hepatic lobules. (nci).

parent_id:7727

***level:4

type:child

term:Kidney

definition:The organs of the urinary tract located in the retroperitoneal cavity adjacent to the spine and composed of the renal cortex and the renal medulla. (nci).

parent_id:7727

***level:4

type:child

synonym:Kidneys

term:Biofluid and excreta

definition:A liquid, semi-solid or solid material originating in the body.

parent_id:7725

**level:3

type:parent

term:Feces

definition:The material discharged from the bowel during defecation. It consists of undigested food, intestinal mucus, epithelial cells, and bacteria.

parent_id:7731

***level:4

type:child

synonym:Fecal

synonym:Stool

synonym:Faecal

synonym:Faeces

term:Urine

definition:Excretion in liquid state processed by the kidney.

parent_id:7731

***level:4

type:child

term:Blood

definition:A liquid tissue with the primary function of transporting oxygen and carbon dioxide (nci). it supplies the tissues with nutrients, removes waste products, and contains various components of the immune system defending the body against infection.

parent_id:7731

***level:4

type:child

term:Sweat

definition:Secretion produced by a sweat gland.

parent_id:7731

***level:4

type:child

term:Subcellular

definition:An anatomical organizational level including a component within a biological cell .

parent_id:7725

**level:3

type:parent

term:Cytoplasm

definition:The portion of the cell contained within the plasma membrane but excluding the nucleus.

parent_id:7730

***level:4

type:child

synonym:Cytoplasma

term:Lysosome

definition:В A sac-like compartment inside a cell that has enzymes that can break down cellular components that need to be destroyed. (NCI).

parent_id:7730

***level:4

type:child

term:Cell and elements

definition:An anatomical organizational level comprising of a single cell (or a fragment in some exceptions). a cell is defined by its type or function. it is the smallest unit of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid.

parent_id:7725

**level:3

type:parent

term:Extracellular

definition:The space external to the outermost structure of a cell.

parent_id:7732

***level:4

type:child

synonym:Extracellular region

term:Element

definition:

parent_id:7732

***level:4

type:parent

term:Process

definition:Biological or chemical events, or a series thereof, leading to a known function or end-product.

parent_id:

level:1

type:parent

term:Naturally occurring process

definition:Naturally-occurring molecular events or a series thereof, leading to a known function or end-product.

parent_id:7659

*level:2

type:parent

term:Biological process

definition:Biological or chemical events or a series thereof, leading to a known function or end-product within an organism.

parent_id:7660

**level:3

type:parent

term:Biochemical pathway

definition:A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.

parent_id:7661

***level:4

type:parent

term:Role

definition:The purpose or function assumed by a chemical, either naturally or as intended by humans .

parent_id:

level:1

type:parent

term:Biological role

definition:The biological function of a chemical. the biological role answers the question how a chemical is involved in molecular processes in an organism. this can include biochemical effects of non-endogenous chemicals, which are also assigned an industrial application such as pharmaceuticals. the biological role is limited to cellular levls, and will not include role at system process level, such as a chemical which has a role in a disease.

parent_id:7671

*level:2

type:parent

term:Drug metabolite

definition:

parent_id:7672

**level:3

type:child

term:Waste product

definition:A chemical that is generated in a metabolic process and is destined to be excreted from the body. It commonly consists of water, nitrogenous compounds or carbon dioxide and can be a metabolic byproduct or a degradation product (such as urobilin metabolised from bilirubin which is a degradation product of hemoglobin).

parent_id:7672

**level:3

type:child

状态
Solid
实验性质
1:

kind:water_solubility

value:780.0 mg/mL

source:

2:

kind:melting_point

value:102 - 103 °C

source:

预测性质
1:

kind:logp

value:-3.01

source:ALOGPS

2:

kind:logs

value:0.23

source:ALOGPS

3:

kind:solubility

value:586 g/L

source:ALOGPS

4:

kind:logp

value:-4.7

source:ChemAxon

5:

kind:pka_strongest_acidic

value:11.25

source:ChemAxon

6:

kind:pka_strongest_basic

value:-3

source:ChemAxon

7:

kind:iupac

value:(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol

source:ChemAxon

8:

kind:average_mass

value:342.2965

source:ChemAxon

9:

kind:mono_mass

value:342.116211546

source:ChemAxon

10:

kind:smiles

value:OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O

source:ChemAxon

11:

kind:formula

value:C12H22O11

source:ChemAxon

12:

kind:inchi

value:InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5-,6+,7-,8+,9-,10-,11+,12-/m1/s1

source:ChemAxon

13:

kind:inchikey

value:GUBGYTABKSRVRQ-DKBJLJRDSA-N

source:ChemAxon

14:

kind:polar_surface_area

value:189.53

source:ChemAxon

15:

kind:refractivity

value:68.34

source:ChemAxon

16:

kind:polarizability

value:31.43

source:ChemAxon

17:

kind:rotatable_bond_count

value:4

source:ChemAxon

18:

kind:acceptor_count

value:11

source:ChemAxon

19:

kind:donor_count

value:8

source:ChemAxon

20:

kind:physiological_charge

value:0

source:ChemAxon

21:

kind:formal_charge

value:0

source:ChemAxon

22:

kind:number_of_rings

value:2

source:ChemAxon

23:

kind:bioavailability

value:No

source:ChemAxon

24:

kind:rule_of_five

value:No

source:ChemAxon

25:

kind:ghose_filter

value:No

source:ChemAxon

26:

kind:veber_rule

value:No

source:ChemAxon

27:

kind:mddr_like_rule

value:No

source:ChemAxon

1:

type:Specdb::MsMs

spectrum_id:257

2:

type:Specdb::MsMs

spectrum_id:258

3:

type:Specdb::MsMs

spectrum_id:259

4:

type:Specdb::MsMs

spectrum_id:300682

5:

type:Specdb::MsMs

spectrum_id:300683

6:

type:Specdb::MsMs

spectrum_id:300684

7:

type:Specdb::MsMs

spectrum_id:343009

8:

type:Specdb::MsMs

spectrum_id:343010

9:

type:Specdb::MsMs

spectrum_id:343011

10:

type:Specdb::MsMs

spectrum_id:2423731

11:

type:Specdb::MsMs

spectrum_id:2423732

12:

type:Specdb::MsMs

spectrum_id:2423733

13:

type:Specdb::MsMs

spectrum_id:2515392

14:

type:Specdb::MsMs

spectrum_id:2515393

15:

type:Specdb::MsMs

spectrum_id:2515394

16:

type:Specdb::NmrTwoD

spectrum_id:978

17:

type:Specdb::NmrTwoD

spectrum_id:1180

18:

type:Specdb::NmrOneD

spectrum_id:1125

19:

type:Specdb::NmrOneD

spectrum_id:1181

20:

type:Specdb::NmrOneD

spectrum_id:5932

21:

type:Specdb::NmrOneD

spectrum_id:5933

22:

type:Specdb::NmrOneD

spectrum_id:5934

23:

type:Specdb::NmrOneD

spectrum_id:5935

24:

type:Specdb::NmrOneD

spectrum_id:5936

25:

type:Specdb::NmrOneD

spectrum_id:5937

26:

type:Specdb::NmrOneD

spectrum_id:5938

27:

type:Specdb::NmrOneD

spectrum_id:5939

28:

type:Specdb::NmrOneD

spectrum_id:5940

29:

type:Specdb::NmrOneD

spectrum_id:5941

30:

type:Specdb::NmrOneD

spectrum_id:5942

31:

type:Specdb::NmrOneD

spectrum_id:5943

32:

type:Specdb::NmrOneD

spectrum_id:5944

33:

type:Specdb::NmrOneD

spectrum_id:5945

34:

type:Specdb::NmrOneD

spectrum_id:5946

35:

type:Specdb::NmrOneD

spectrum_id:5947

36:

type:Specdb::NmrOneD

spectrum_id:5948

37:

type:Specdb::NmrOneD

spectrum_id:5949

38:

type:Specdb::NmrOneD

spectrum_id:5950

39:

type:Specdb::NmrOneD

spectrum_id:5951

40:

type:Specdb::NmrOneD

spectrum_id:166525

41:

type:Specdb::CMs

spectrum_id:15658

42:

type:Specdb::CMs

spectrum_id:37332

43:

type:Specdb::CMs

spectrum_id:148295

44:

type:Specdb::CMs

spectrum_id:148297

45:

type:Specdb::CMs

spectrum_id:148299

46:

type:Specdb::CMs

spectrum_id:148301

47:

type:Specdb::CMs

spectrum_id:148304

48:

type:Specdb::CMs

spectrum_id:148306

49:

type:Specdb::CMs

spectrum_id:148308

50:

type:Specdb::CMs

spectrum_id:148310

51:

type:Specdb::CMs

spectrum_id:148312

52:

type:Specdb::CMs

spectrum_id:173951

53:

type:Specdb::CMs

spectrum_id:279668

光谱
生物学性质
1:

cellular:(1):Cytoplasm

cellular:(2):Extracellular

cellular:(3):Lysosome

2:

biospecimen:(1):Blood

biospecimen:(2):Feces

biospecimen:(3):Sweat

biospecimen:(4):Urine

3:

tissue:(1):Kidney

tissue:(2):Liver

tissue:(3):Placenta

tissue:(4):Platelet

4:

[1]:

name:Glycogen synthetase deficiency

smpdb_id:SMP00552

kegg_map_id:

[2]:

name:Glycogenosis, Type III. Cori disease, Debrancher glycogenosis

smpdb_id:SMP00553

kegg_map_id:

[3]:

name:Glycogenosis, Type IV. Amylopectinosis, Anderson disease

smpdb_id:SMP00554

kegg_map_id:

[4]:

name:Glycogenosis, Type VI. Hers disease

smpdb_id:SMP00555

kegg_map_id:

[5]:

name:Mucopolysaccharidosis VI. Sly syndrome

smpdb_id:SMP00556

kegg_map_id:

[6]:

name:Starch and Sucrose Metabolism

smpdb_id:SMP00058

kegg_map_id:map00500

[7]:

name:Sucrase-isomaltase deficiency

smpdb_id:SMP00557

kegg_map_id:

正常浓度
1:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Infant (0-1 year old)

subject_sex:Both

subject_condition:Normal

2:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

3:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

4:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

5:

biospecimen:Feces

concentration_value:

concentration_units:

subject_age:Not Specified

subject_sex:Not Specified

subject_condition:Normal

6:

biospecimen:Sweat

concentration_value:

concentration_units:

subject_age:Adult

subject_sex:Both

subject_condition:Normal

7:

biospecimen:Urine

concentration_value:16.424 +/- 6.538

concentration_units:umol/mmol creatinine

subject_age:Children (1 - 13 years old)

subject_sex:Not Specified

subject_condition:Normal

8:

biospecimen:Urine

concentration_value:6.0 (1.3-21.4)

concentration_units:umol/mmol creatinine

subject_age:Adult (>18 years old)

subject_sex:Both

subject_condition:Normal

9:

biospecimen:Urine

concentration_value:6.14 +/- 5.12

concentration_units:umol/mmol creatinine

subject_age:Infant (0-1 year old)

subject_sex:Both

subject_condition:Normal

异常浓度
1:

biospecimen:Blood

concentration_value:1169.0 +/- 526.0

concentration_units:uM

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Peritoneal dialysis

2:

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Colorectal Cancer

3:

biospecimen:Feces

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Colorectal cancer

4:

biospecimen:Urine

concentration_value:8.332 +/- 5.36

concentration_units:umol/mmol creatinine

patient_age:Children (1 - 13 years old)

patient_sex:Not Specified

patient_information:Eosinophilic esophagitis

5:

biospecimen:Urine

concentration_value:

concentration_units:

patient_age:Adult (>18 years old)

patient_sex:Both

patient_information:Bladder cancer

疾病参考
1:

name:Peritoneal dialysis

omim_id:

[1]:

reference_text:Garcia-Lopez E, Anderstam B, Heimburger O, Amici G, Werynski A, Lindholm B: Determination of high and low molecular weight molecules of icodextrin in plasma and dialysate, using gel filtration chromatography, in peritoneal dialysis patients. Perit Dial Int. 2005 Mar-Apr;25(2):181-91.

pubmed_id:15796147

2:

name:Colorectal cancer

omim_id:114500

[1]:

reference_text:Ishiwata S, Itoh K, Yamaguchi T, Ishida N, Mizugaki M: Comparison of serum and urinary levels of modified nucleoside, 1-methyladenosine, in cancer patients using a monoclonal antibody-based inhibition ELISA. Tohoku J Exp Med. 1995 May;176(1):61-8.

pubmed_id:7482520

[2]:

reference_text:Monleon D, Morales JM, Barrasa A, Lopez JA, Vazquez C, Celda B: Metabolite profiling of fecal water extracts from human colorectal cancer. NMR Biomed. 2009 Apr;22(3):342-8. doi: 10.1002/nbm.1345.

pubmed_id:19006102

[3]:

reference_text:Weir TL, Manter DK, Sheflin AM, Barnett BA, Heuberger AL, Ryan EP: Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults. PLoS One. 2013 Aug 6;8(8):e70803. doi: 10.1371/journal.pone.0070803. Print 2013.

pubmed_id:23940645

[4]:

reference_text:Phua LC, Chue XP, Koh PK, Cheah PY, Ho HK, Chan EC: Non-invasive fecal metabonomic detection of colorectal cancer. Cancer Biol Ther. 2014 Apr;15(4):389-97. doi: 10.4161/cbt.27625. Epub 2014 Jan 14.

pubmed_id:24424155

[5]:

reference_text:Ritchie SA, Ahiahonu PW, Jayasinghe D, Heath D, Liu J, Lu Y, Jin W, Kavianpour A, Yamazaki Y, Khan AM, Hossain M, Su-Myat KK, Wood PL, Krenitsky K, Takemasa I, Miyake M, Sekimoto M, Monden M, Matsubara H, Nomura F, Goodenowe DB: Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. BMC Med. 2010 Feb 15;8:13. doi: 10.1186/1741-7015-8-13.

pubmed_id:20156336

[6]:

reference_text:Qiu Y, Cai G, Su M, Chen T, Zheng X, Xu Y, Ni Y, Zhao A, Xu LX, Cai S, Jia W: Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS. J Proteome Res. 2009 Oct;8(10):4844-50. doi: 10.1021/pr9004162.

pubmed_id:19678709

[7]:

reference_text:Cheng Y, Xie G, Chen T, Qiu Y, Zou X, Zheng M, Tan B, Feng B, Dong T, He P, Zhao L, Zhao A, Xu LX, Zhang Y, Jia W: Distinct urinary metabolic profile of human colorectal cancer. J Proteome Res. 2012 Feb 3;11(2):1354-63. doi: 10.1021/pr201001a. Epub 2011 Dec 28.

pubmed_id:22148915

[8]:

reference_text:Ni Y, Xie G, Jia W: Metabonomics of human colorectal cancer: new approaches for early diagnosis and biomarker discovery. J Proteome Res. 2014 Sep 5;13(9):3857-70. doi: 10.1021/pr500443c. Epub 2014 Aug 14.

pubmed_id:25105552

[9]:

reference_text:Ikeda A, Nishiumi S, Shinohara M, Yoshie T, Hatano N, Okuno T, Bamba T, Fukusaki E, Takenawa T, Azuma T, Yoshida M: Serum metabolomics as a novel diagnostic approach for gastrointestinal cancer. Biomed Chromatogr. 2012 May;26(5):548-58. doi: 10.1002/bmc.1671. Epub 2011 Jul 20.

pubmed_id:21773981

[10]:

reference_text:Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18.

pubmed_id:25037050

[11]:

reference_text:Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ: Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations. PLoS One. 2016 Mar 25;11(3):e0152126. doi: 10.1371/journal.pone.0152126. eCollection 2016.

pubmed_id:27015276

[12]:

reference_text:Lin Y, Ma C, Liu C, Wang Z, Yang J, Liu X, Shen Z, Wu R: NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in patients with colorectal cancer. Oncotarget. 2016 May 17;7(20):29454-64. doi: 10.18632/oncotarget.8762.

pubmed_id:27107423

[13]:

reference_text:Brown DG, Rao S, Weir TL, O'Malia J, Bazan M, Brown RJ, Ryan EP: Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool. Cancer Metab. 2016 Jun 6;4:11. doi: 10.1186/s40170-016-0151-y. eCollection 2016.

pubmed_id:27275383

[14]:

reference_text:Wang X, Wang J, Rao B, Deng L: Gut flora profiling and fecal metabolite composition of colorectal cancer patients and healthy individuals. Exp Ther Med. 2017 Jun;13(6):2848-2854. doi: 10.3892/etm.2017.4367. Epub 2017 Apr 20.

pubmed_id:28587349

[15]:

reference_text:Silke Matysik, Caroline Ivanne Le Roy, Gerhard Liebisch, Sandrine Paule Claus. Metabolomics of fecal samples: A practical consideration. Trends in Food Science & Technology. Vol. 57, Part B, Nov. 2016, p.244-255: http://www.sciencedirect.com/science/article/pii/S0924224416301984

3:

name:Eosinophilic esophagitis

omim_id:610247

[1]:

reference_text:Mordechai, Hien, and David S. Wishart

pubmed_id:

KEGG数据库编号
C00208
DrugBank数据库编号
foodb数据库编号
FDB001193
ChemSpider数据库编号
9166684
公共化学化合物编号
10991489
PDB数据库编号
生物利益的化学实体数据库编号
47937
knapsack数据库编号
C00001140
维基百科编号
Maltose
代谢途径的数据库编号
苯酚资源管理器化合物数据库编号
比格数据库编号
34261
梅林编号
413
虚拟机身份证编号
MALT
fbonto数据库编号
综合参考
Pedersen, Sven; Vang Hendriksen, Hanne. Method for production of maltose and/or enzymatically modified starch. PCT Int. Appl. (2001), 99 pp.
一般参考
1:

protein_accession:HMDBP00367

name:Glycogen debranching enzyme

uniprot_id:P35573

gene_name:AGL

protein_type:Enzyme

2:

protein_accession:HMDBP01817

name:Lysosomal alpha-glucosidase

uniprot_id:P10253

gene_name:GAA

protein_type:Enzyme

3:

protein_accession:HMDBP02083

name:Alpha-amylase 1

uniprot_id:P04745

gene_name:AMY1A

protein_type:Unknown

4:

protein_accession:HMDBP02146

name:Alpha-amylase 2B

uniprot_id:P19961

gene_name:AMY2B

protein_type:Unknown

5:

protein_accession:HMDBP03069

name:Maltase-glucoamylase, intestinal

uniprot_id:O43451

gene_name:MGAM

protein_type:Enzyme

6:

protein_accession:HMDBP05979

name:Neutral alpha-glucosidase C

uniprot_id:Q8TET4

gene_name:GANC

protein_type:Enzyme

蛋白质结合
1:

reference_text:Lu J, Willis AC, Reid KB: Purification, characterization and cDNA cloning of human lung surfactant protein D. Biochem J. 1992 Jun 15;284 ( Pt 3):795-802.

pubmed_id:1339284

2:

reference_text:Rubaltelli FF, Biadaioli R, Pecile P, Nicoletti P: Intestinal flora in breast- and bottle-fed infants. J Perinat Med. 1998;26(3):186-91.

pubmed_id:9773376

3:

reference_text:Andrews RK, Suzuki-Inoue K, Shen Y, Tulasne D, Watson SP, Berndt MC: Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. Blood. 2002 Jun 1;99(11):4219-21.

pubmed_id:12010829

4:

reference_text:Hirooka EY, Muller EE, Freitas JC, Vicente E, Yoshimoto Y, Bergdoll MS: Enterotoxigenicity of Staphylococcus intermedius of canine origin. Int J Food Microbiol. 1988 Dec;7(3):185-91.

pubmed_id:3275321

5:

reference_text:Daly JJ, Sherman JK, Green L, Hostetler TL: Survival of Trichomonas vaginalis in human semen. Genitourin Med. 1989 Apr;65(2):106-8.

pubmed_id:2787774

6:

reference_text:Sherman JK, Hostetler TL, McHenry K, Daly JJ: Cryosurvival of Trichomonas vaginalis during cryopreservation of human semen. Cryobiology. 1991 Jun;28(3):246-50.

pubmed_id:1864083

7:

reference_text:van Leeuwen L: New saccharogenic determination of alpha-amylase in serum and urine. Clin Chem. 1979 Feb;25(2):215-7.

pubmed_id:215341

8:

reference_text:Miller LJ, Malagelada JR, Taylor WF, Go VL: Intestinal control of human postprandial gastric function: the role of components of jejunoileal chyme in regulating gastric secretion and gastric emptying. Gastroenterology. 1981 Apr;80(4):763-9.

pubmed_id:7202948

9:

reference_text:Roy E, Stavropoulos E, Brennan J, Coade S, Grigorieva E, Walker B, Dagg B, Tascon RE, Lowrie DB, Colston MJ, Jolles S: Therapeutic efficacy of high-dose intravenous immunoglobulin in Mycobacterium tuberculosis infection in mice. Infect Immun. 2005 Sep;73(9):6101-9.

pubmed_id:16113331

10:

reference_text:Wyss C, Choi BK, Schupbach P, Guggenheim B, Gobel UB: Treponema maltophilum sp. nov., a small oral spirochete isolated from human periodontal lesions. Int J Syst Bacteriol. 1996 Jul;46(3):745-52.

pubmed_id:8782684

11:

reference_text:Morse DR, Schacterle GR, Furst L, Zaydenberg M, Pollack RL: Oral digestion of a complex-carbohydrate cereal: effects of stress and relaxation on physiological and salivary measures. Am J Clin Nutr. 1989 Jan;49(1):97-105.

pubmed_id:2463752

12:

reference_text:Yamamoto T, Kajiura S, Hirai Y, Watanabe T: Capnocytophaga haemolytica sp. nov. and Capnocytophaga granulosa sp. nov., from human dental plaque. Int J Syst Bacteriol. 1994 Apr;44(2):324-9.

pubmed_id:8186098

13:

reference_text:Zhu J, Marchant RE: Dendritic saccharide surfactant polymers as antifouling interface materials to reduce platelet adhesion. Biomacromolecules. 2006 Apr;7(4):1036-41.

pubmed_id:16602718

14:

reference_text:Lingstrom P, Birkhed D, Granfeldt Y, Bjorck I: pH measurements of human dental plaque after consumption of starchy foods using the microtouch and the sampling method. Caries Res. 1993;27(5):394-401.

pubmed_id:8242677

15:

reference_text:Leth-Larsen R, Holmskov U, Hojrup P: Structural characterization of human and bovine lung surfactant protein D. Biochem J. 1999 Nov 1;343 Pt 3:645-52.

pubmed_id:10527944

16:

reference_text:Janoshazi A, Solomon AK: Initial steps of alpha- and beta-D-glucose binding to intact red cell membrane. J Membr Biol. 1993 Mar;132(2):167-78.

pubmed_id:8496948

17:

reference_text:Tiwari F, Singh DK: Behavioural responses of the snail Lymnaea acuminata to carbohydrates in snail-attractant pellets. Naturwissenschaften. 2004 Aug;91(8):378-80. Epub 2004 Jun 2.

pubmed_id:15309310

18:

reference_text:Chiba S, Hiromi K, Minamiura N, Ohnishi M, Shimomura T, Suga K, Suganuma T, Tanaka A, Tomioka S, Yamamoto T: Quantitative study on anomeric forms of glucose produced by alpha-glucosidases. J Biochem. 1979 May;85(5):1135-41.

pubmed_id:376499

19:

reference_text:McCue JP, Hein RH, Tenold R: Three generations of immunoglobulin G preparations for clinical use. Rev Infect Dis. 1986 Jul-Aug;8 Suppl 4:S374-81.

pubmed_id:3092303

20:

reference_text:Dorner KM: Quantitative determination of lactose, maltose, and sucrose in urine. Eur J Pediatr. 1977 Aug 23;126(1-2):45-52.

pubmed_id:902663

21:

reference_text:Sigman-Grant M, Morita J: Defining and interpreting intakes of sugars. Am J Clin Nutr. 2003 Oct;78(4):815S-826S.

pubmed_id:14522745

22:

reference_text:Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043.

pubmed_id:32033212

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