华法林
临床注释ID
655384733
药物名称(英)
warfarin
变异单倍型
rs7294
基因
VKORC1
证据级别
1B
水平覆盖
水平修饰符
Tier 1 VIP
表现型类别(英)
Dosage
表现型类别
剂量
分数
43.25
PMID计数
21
计数的证据
22
表现型
表现型(英)
最新日期
2021/11/19 0:00:00
URL
https://www.pharmgkb.org/clinicalAnnotation/655384733
专业人口(英)
专业人口
临床证据
id证据的ID总结
3204 981500585 Allele T is associated with increased dose of warfarin in people with Myocardial Infarction as compared to allele C.
3203 981483987 Genotypes CT + TT are associated with increased dose of warfarin in people with mechanical heart valve replacement as compared to genotype CC.
3202 1451589762 Genotypes CT + TT are associated with increased dose of warfarin as compared to genotype CC.
3201 1451340144 Genotypes CT + TT are associated with increased dose of warfarin as compared to genotype CC.
1976 769277912 Genotype CT is associated with increased dose of warfarin as compared to genotype CC.
1975 827649690 Allele T is associated with increased dose of warfarin as compared to allele C.
1974 769277903 Genotype TT is associated with increased dose of warfarin as compared to genotypes CC + CT.
1973 1447519684 Genotypes CT + TT are associated with increased dose of warfarin as compared to genotype CC.
1972 1448276167 Genotype TT is associated with increased dose of warfarin as compared to genotype CC.
1971 1450979280 Allele T is associated with decreased dose of warfarin as compared to allele C.
1970 1444694686 Genotype CC is associated with decreased concentrations of warfarin in people with heart valve replacement as compared to genotypes CT + TT.
1969 1444694676 Genotype CC is not associated with dose of warfarin in people with heart valve replacement as compared to genotypes CT + TT.
1968 1185002294 Allele T is associated with increased dose of warfarin as compared to allele C.
1967 1184756163 Allele T is associated with increased dose of warfarin in people with heart valve replacement as compared to allele C.
1966 1184483453 Allele C is associated with decreased dose of warfarin as compared to allele T.
1965 1184472447 Allele T is associated with increased dose of warfarin as compared to allele C.
1964 1183704904 Genotype CC is associated with decreased dose of warfarin as compared to genotypes CT + TT.
1963 1183697701 Genotypes CT + TT is associated with increased dose of warfarin in people with Cardiovascular Diseases as compared to genotype CC.
1962 1183697222 Genotype TT is associated with increased dose of warfarin as compared to genotypes CC + CT.
1961 655388073 Allele T is associated with increased dose of warfarin.
1960 827567329 Allele C is associated with decreased dose of warfarin as compared to allele T.
1959 982034243 Allele T is associated with increased dose of warfarin as compared to allele C.
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