首 页
医药产品
医保药品
中标目录
医药招标
数据中心
医学资料
医药新闻
医药展会
OTC药品
保健品
医疗器械
处方药
专科药
中医药
器械中标目录
药品批发行情
求购信息
医药下载
药价简讯
当前位置:药药网 / 数据中心 / 临床注释-2,变异和临床注释数据
华法林
临床注释ID
655385024
药物名称(英)
warfarin
变异单倍型
rs2359612
基因
VKORC1
证据级别
1B
水平覆盖
水平修饰符
Tier 1 VIP
表现型类别(英)
Dosage
表现型类别
剂量
分数
38.25
PMID计数
14
计数的证据
15
表现型
表现型(英)
最新日期
2021/11/19 0:00:00
URL
https://www.pharmgkb.org/clinicalAnnotation/655385024
专业人口(英)
专业人口
临床等位基因
id
等位基因
注释文本
1377
AG
Patients with the rs2359612 AG genotype may require a decreased dose of warfarin as compared to patients with the GG genotype. Other genetic and clinical factors may also influence dose of warfarin.
1376
AA
Patients with the rs2359612 AA genotype may require a decreased dose of warfarin as compared to patients with the GG genotype. Other genetic and clinical factors may also influence dose of warfarin.
1064
GG
Patients with the rs2359612 GG genotype may require an increased dose of warfarin as compared to patients with the AG or AA genotype. Other genetic and clinical factors may also influence dose of warfarin.
临床证据
id
证据的ID
总结
3191
613977249
Allele A is associated with decreased dose of warfarin.
3190
1447519944
Allele A is associated with decreased dose of warfarin as compared to allele G.
3189
1447519671
Genotypes AA + AG are associated with decreased dose of warfarin as compared to genotype GG.
3188
1448276172
Genotype GG is associated with increased dose of warfarin as compared to genotypes AA + AG.
3187
1448106998
Allele A is associated with decreased dose of warfarin as compared to allele G.
3186
1450980780
Genotypes AA + AG is associated with decreased time to the first INR within the therapeutic range when treated with warfarin as compared to genotype GG.
3185
1450980680
Genotype AA is associated with decreased dose of warfarin as compared to genotype GG.
3184
1184472436
Allele A is associated with decreased dose of warfarin as compared to allele G.
3183
1183704894
Genotype GG is associated with increased dose of warfarin as compared to genotypes AA + AG.
3182
1183701268
Allele A is associated with dose of warfarin.
3181
827567321
Allele A is associated with decreased dose of warfarin as compared to allele G.
3180
982044349
Allele G is associated with increased dose of warfarin as compared to allele A.
3179
982038164
Allele A is associated with decreased warfarin dose when treated with warfarin as compared to allele G.
3178
1451589745
Genotypes AG + GG are associated with increased dose of warfarin as compared to genotype AA.
3177
1451340084
Genotypes AA + AG are associated with decreased dose of warfarin as compared to genotype GG.
临床病史
id
类型
评论
1538
Update
Added PMIDs 31869433 and 31114289 to evidence
1537
Update
CA score added as part of scoring system release. LOE assigned following curator review.
1536
Update
updated text
1535
Update
Switched from haplotype VA to variant based one.
1534
Update
Reviewed.
1533
Update
Added PMID 18466099, 19752777; re-worded the CA sentences.
最新招商产品
更多>>
韩特润目冷敷凝胶贴牌定制代..
济南康民药业..
全国||不限
韩特润目冷敷凝胶贴牌定制代..
济南康民药业..
全国||不限
韩特乳康冷敷凝胶贴牌定制代..
济南康民药业..
全国||不限
韩特筋骨冷敷凝胶贴牌定制代..
济南康民药业..
全国||不限
韩特筋骨冷敷凝胶贴牌定制代..
济南康民药业..
全国||不限
韩特筋骨冷敷凝胶贴牌定制代..
济南康民药业..
全国||不限
韩特筋骨医用冷敷贴贴牌定制..
济南康民药业..
全国||不限
韩特筋骨医用冷敷贴贴牌定制..
济南康民药业..
全国||不限
韩特前列腺冷敷凝胶贴牌定制..
济南康民药业..
全国||不限
韩特前列腺医用冷敷贴贴牌定..
济南康民药业..
全国||不限
网站地图
-
网站开发
-
网站简介
-
会员服务
-
法律声明
-
联系我们
-
药品招商频道
-
药品信息排行
-
2018年版国家基本药物目录
-
意见反馈
免责声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责,医药网对此不承担任何责任。
相关链接:
医药研究数据
|
医药资料
|
SDA药品评审中心
|
中医网
|
中药处方系统
|
爱视立眼贴
专业提供药品信息、药品招商、药品代理、保健品招商、医药原料采购供应的中国药品信息网站平台
版权所有 © 2003-2028 盗冒必究 客服热线:0575-83552251 / 13754370441 QQ客服:
浙ICP备16010490号-2
增值电信业务经营许可证:
浙B2-20220931
互联网药品信息服务资格证书编号:
(浙)-经营性2023-0215
浙公网安备:330683240604819103159
医药代理商群1:
医药代理商群2:
医药代理商群3: