华法林
临床注释ID
655385024
药物名称(英)
warfarin
变异单倍型
rs2359612
基因
VKORC1
证据级别
1B
水平覆盖
水平修饰符
Tier 1 VIP
表现型类别(英)
Dosage
表现型类别
剂量
分数
38.25
PMID计数
14
计数的证据
15
表现型
表现型(英)
最新日期
2021/11/19 0:00:00
URL
https://www.pharmgkb.org/clinicalAnnotation/655385024
专业人口(英)
专业人口
临床证据
id证据的ID总结
3191 613977249 Allele A is associated with decreased dose of warfarin.
3190 1447519944 Allele A is associated with decreased dose of warfarin as compared to allele G.
3189 1447519671 Genotypes AA + AG are associated with decreased dose of warfarin as compared to genotype GG.
3188 1448276172 Genotype GG is associated with increased dose of warfarin as compared to genotypes AA + AG.
3187 1448106998 Allele A is associated with decreased dose of warfarin as compared to allele G.
3186 1450980780 Genotypes AA + AG is associated with decreased time to the first INR within the therapeutic range when treated with warfarin as compared to genotype GG.
3185 1450980680 Genotype AA is associated with decreased dose of warfarin as compared to genotype GG.
3184 1184472436 Allele A is associated with decreased dose of warfarin as compared to allele G.
3183 1183704894 Genotype GG is associated with increased dose of warfarin as compared to genotypes AA + AG.
3182 1183701268 Allele A is associated with dose of warfarin.
3181 827567321 Allele A is associated with decreased dose of warfarin as compared to allele G.
3180 982044349 Allele G is associated with increased dose of warfarin as compared to allele A.
3179 982038164 Allele A is associated with decreased warfarin dose when treated with warfarin as compared to allele G.
3178 1451589745 Genotypes AG + GG are associated with increased dose of warfarin as compared to genotype AA.
3177 1451340084 Genotypes AA + AG are associated with decreased dose of warfarin as compared to genotype GG.
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