醋硝香豆素
临床注释ID
981204044
药物名称(英)
acenocoumarol
变异单倍型
rs9923231
基因
VKORC1
证据级别
1A
水平覆盖
水平修饰符
Tier 1 VIP
表现型类别(英)
Dosage
表现型类别
剂量
分数
147.75
PMID计数
20
计数的证据
25
表现型
表现型(英)
最新日期
2021/3/24 0:00:00
URL
https://www.pharmgkb.org/clinicalAnnotation/981204044
专业人口(英)
专业人口
临床证据
id证据的ID总结
115 1448259376 Genotype CC is associated with increased dose of acenocoumarol in people with Atrial Fibrillation or venous thromboembolism as compared to genotypes CT + TT.
114 1448259324 Allele T is associated with dose of acenocoumarol.
113 1448259259 Allele T is associated with dose of acenocoumarol or phenprocoumon.
112 1448255537 Genotypes CT + TT are associated with decreased dose of acenocoumarol in people with Rheumatic Heart Disease as compared to genotype CC.
111 1184511557 Genotypes CT + TT is associated with decreased dose of acenocoumarol as compared to genotype CC.
110 1183680104 Genotype TT is associated with decreased acenocoumarol dose when treated with acenocoumarol in people with Atrial Fibrillation as compared to genotype CC.
109 827814729 Allele T is associated with decreased dose of acenocoumarol as compared to allele C.
108 982031298 Genotype TT is associated with decreased dose of acenocoumarol as compared to genotype CC.
107 982031288 Genotype CT is associated with decreased dose of acenocoumarol as compared to genotype CC.
106 982015093 Genotype TT is associated with decreased dose of acenocoumarol as compared to genotypes CC + CT.
105 982010039 Genotype CC is associated with increased dose of acenocoumarol as compared to genotype CT.
104 982010028 Genotype TT is not associated with dose of acenocoumarol as compared to genotype CT.
103 982006735 Genotype CT is associated with decreased dose of acenocoumarol as compared to genotype CC.
102 982006724 Genotype TT is associated with decreased dose of acenocoumarol as compared to genotypes CC + CT.
101 981954427 Genotype CC is associated with increased dose of acenocoumarol as compared to genotypes CT + TT.
100 981940056 Genotype CC is associated with increased dose of acenocoumarol as compared to genotypes CT + TT.
99 981859299 Genotype TT is associated with decreased dose of acenocoumarol as compared to genotype CC.
98 981502435 Genotypes CC + CT are associated with increased dose of acenocoumarol or warfarin as compared to genotype TT.
97 1444707179 Genotypes CT + TT are associated with decreased dose of acenocoumarol as compared to genotype CC.
96 1444706967 Genotype TT are associated with decreased dose of acenocoumarol as compared to genotype CC.
95 1444705842 Genotypes CT + TT are associated with decreased dose of acenocoumarol as compared to genotype CC.
94 1444705565 Allele T is associated with decreased dose of acenocoumarol as compared to allele C.
93 1444699595 Allele T is associated with decreased dose of acenocoumarol as compared to allele C.
92 1184754659 Allele T is associated with decreased dose of acenocoumarol as compared to allele C.
91 PA166104938 Annotation of DPWG Guideline for acenocoumarol and VKORC1
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