Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1183618857
总结
CYP2D6 *4 + *5 are associated with increased serum concentrations of S(+)-mirtazapine, mirtazapine S(+)/R(-) ratios and S(+)-N-desmethylmirtazapine when treated with mirtazapine in people with Mental Disorders as compared to CYP2D6 *1/*1.