Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1449732030
总结
Genotypes CT + TT are associated with increased risk of Drug Toxicity and Neutropenia when treated with capecitabine or fluorouracil in people with Colorectal Neoplasms as compared to genotype CC.
得分
This annotation is not used for clinical annotation scoring. From the discussion section: "no associations with common variants remained statistically significant after correction"