Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444704497
总结
CYP2C19 *2/*2 + *2/*3 + *3/*3 (assigned as poor metabolizers phenotype) are associated with increased risk of Death, Myocardial Infarction and Stroke when treated with clopidogrel in people with Coronary Artery Disease as compared to CYP2C19 *1/*1 (assigned as normal metabolizers phenotype) .