Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1183618387
总结
CYP2D6 *5/*10 is associated with increased mean nortriptyline concentrations and nortriptyline concentrations per unit dose of the medication when treated with nortriptyline in people with Depressive Disorder, Major as compared to CYP2D6 *1/*1.