Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/981344956
总结
CYP2A6 *4A + *10 + *9A is associated with decreased plasma and urinary ratio of metabolites trans-3'-hydroxycotinine to cotinine (3HC/COT) when exposed to nicotine in healthy individuals as compared to CYP2A6 *1A.