Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/637879745
总结
Genotype AA is associated with increased risk of Drug Toxicity when treated with methotrexate in people with Precursor Cell Lymphoblastic Leukemia-Lymphoma as compared to genotypes AG + GG.
得分
This annotation is not used for clinical annotation scoring. Overlap of authors and patient cohort with PMID 12453860