Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1183621673
总结
CYP2D6 *5/*36 + *10/*10 + *10/*36 + *21/*36 are associated with decreased oral clearance (CL/F) of flecainide in patients with supraventricular tachyarrhythmia when treated with flecainide as compared to CYP2D6 *1/*1 + *1/*2.