Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1448268166
总结
TPMT *3A + *3C is associated with increased likelihood of Leukopenia and Neutropenia when treated with azathioprine or mercaptopurine in children with Precursor Cell Lymphoblastic Leukemia-Lymphoma as compared to TPMT *1/*1.