Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1184349431
总结
TPMT *1/*3A + *3A/*3A + *1/*3C + *3C/*3C is associated with increased likelihood of Bone Marrow toxicity when treated with azathioprine, mercaptopurine or purine analogues in people with Inflammatory Bowel Diseases as compared to TPMT *1/*1.