Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1183632396
总结
CYP2D6 *1/*2xN + *2/*2xN are associated with increased opioid related adverse events ( immediate pain relief from codeine but stopped taking it due to dizziness and constipation) when treated with codeine in women as compared to CYP2D6 *1/*1.