Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444708297
总结
CYP2D6 *1/*4 + *1/*10 + *1/*5 + *1/*41 + *1/*3 (assigned as heterozygous normal metabolizer phenotype) are associated with increased risk of Recurrence when treated with tamoxifen in women with Breast Neoplasms as compared to CYP2D6 *1/*1 (assigned as normal metabolizer phenotype) .