Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444708269
总结
CYP2D6 *3/*4 + *3/*5 + *4/*4 + *4/*5 (assigned as poor metabolizers phenotype) are associated with increased risk of Recurrence when treated with tamoxifen in women with Breast Neoplasms as compared to CYP2D6 *1/*1 (assigned as normal metabolizer phenotype) .