Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444708216
总结
CYP2D6 *3 + *4 + *5 + *10 + *41 are associated with decreased event-free survival when treated with tamoxifen in women with Breast Neoplasms as compared to CYP2D6 *1/*1 (assigned as normal metabolizer phenotype) .