Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444933205
总结
CYP2D6 *1/*3 + *1/*4 + *1/*5 + *41/*41 + *4/*4 + *4/*5 + *3/*4 + *3/*3 + *3/*5 + *4/*10 + *4/*41 + *5/*41 + *5/*5 are associated with increased risk of Death and Recurrence when treated with antineoplastic agents and tamoxifen in women with Breast Neoplasms as compared to CYP2D6 *1xN/*4 + *1/*1xN + *1/*1 + *1/*41 + *1/*10.