Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444713382
总结
CYP2D6 *5/*10 (assigned as poor metabolizers phenotype) is associated with decreased overall survival when treated with antineoplastic agents and tamoxifen in women with Breast Neoplasms as compared to CYP2D6 *1/*1 + *1/*2 (assigned as normal metabolizers phenotype) .