Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444713343
总结
CYP2D6 *5/*10 (assigned as poor metabolizers phenotype) is associated with decreased Recurrence free survival when treated with antineoplastic agents and tamoxifen in women with Breast Neoplasms as compared to CYP2D6 *1/*10 + *10/*10 + *1/*5 + *2/*10 (assigned as intermediate metabolizers phenotype) .