Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1444709919
总结
CYP2D6 *4/*4 + *4/*41 + *1/*5 + *2/*5 are associated with decreased event-free survival when treated with antineoplastic agents and tamoxifen in people with Breast Neoplasms as compared to CYP2D6 *3/*4 + *4/*9 + *9/*10 + *9/*41 + *41/*41 + *1/*4 + *1/*6 + *2/*4 + *2/*20 + *35/*4 + *1/*10 + *1/*9 + *1/*41 + *35/*10 + *2/*9 + *2/*41 + *35/*41 + *35/*9 + *1/*1 + *2/*2 + *1/*2 + *1/*35 + *1xN/*2.