Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1450370841
总结
CYP2C19 *1/*2 + *2/*2 + *2/*17 (assigned as poor metabolizers and intermediate metabolizers phenotype) are associated with increased platelet aggregation when treated with clopidogrel as compared to CYP2C19 *1/*1 + *1/*17 + *17/*17 (assigned as normal metabolizer and ultra-metabolizer phenotype) .