Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1450372235
总结
Genotypes AC + CC is not associated with risk of Drug Toxicity when treated with capecitabine or fluorouracil in people with Neoplasms as compared to genotype AA.
得分
This annotation is not used for clinical annotation scoring. c.1679T>G was present in 2 of the cases group, but were absent in the controls group. 2 patients developed Grade >=3 toxicity. Non-significance likely due to sample size.