Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1447991202
总结
Genotype AC is not associated with Drug Toxicity when treated with capecitabine or fluorouracil in people with Neoplasms.
得分
This annotation is not used for clinical annotation scoring. Lack of a statistically significant association was likely due to the low frequency of the allele in the population. Only 1 heterozygote variant carrier, which experienced grade 0-2 toxicity