Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1447945597
总结
Genotype AC is not associated with severity of Drug Toxicity when treated with capecitabine or fluorouracil in people with Neoplasms as compared to genotype AA.
得分
This annotation is not used for clinical annotation scoring. Lack of a statistically significant association was likely due to the low frequency of the allele in the population Only two patients carried the varian and both had toxicities.