Variant Phenotype Annotation
证据URL
https://www.pharmgkb.org/variantAnnotation/1451214800
总结
UGT1A1 *28/*28 + *28/*37 is associated with increased severity of Asthenia, Diarrhea and Neutropenia when treated with irinotecan in people with Colorectal Neoplasms as compared to UGT1A1 *1/*1 + *1/*28.